A5036322035- Global Public Health Policies and Epidemiology
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Smoking Behavior and Cessation
- Folate and B Vitamins Research
- Obesity, Physical Activity, Diet
- Regional Development and Innovation
- Child Nutrition and Feeding Issues
- Health and Lifestyle Studies
- Multiple Myeloma Research and Treatments
- Blood properties and coagulation
- Eosinophilic Disorders and Syndromes
- Platelet Disorders and Treatments
- Healthcare Policy and Management
- Public Health and Environmental Issues
- Business, Innovation, and Economy
- Regional Economics and Spatial Analysis
- Nutrition and Health in Aging
- Global Maternal and Child Health
- Global Trade and Competitiveness
- Chronic Myeloid Leukemia Treatments
- Cancer Treatment and Pharmacology
- Kruppel-like factors research
- Global trade and economics
Icesi University
2020-2025
Association pour la Recherche de Thérapeutiques Innovantes en Cancérologie
2023
Ministry of Health and Social Protection
2022
Instituto Nacional de Salud Pública
2022
National University of Río Negro
2021
Universidad de Bogotá Jorge Tadeo Lozano
2012-2019
University of Puerto Rico System
1969-2017
Sergio Arboleda University
2012-2017
The Ohio State University
2014
Universidad Nacional de Colombia
2004-2010
Myeloproliferative neoplasm (MPN) symptoms are troublesome to patients, and alleviation of this burden represents a paramount treatment objective in the development MPN-directed therapies. We aimed assess utility an abbreviated symptom score for most pertinent representative MPN subsequent serial use assessing response therapy.The Neoplasm Symptom Assessment Form total (MPN-SAF TSS) was calculated as mean 10 items from two previously validated scoring systems. Questions focus on fatigue,...
Purpose Polycythemia vera (PV) is a myeloproliferative neoplasm (MPN) associated with disabling symptoms and heightened risk of life-threatening complications. Recent studies have demonstrated the effectiveness JAK inhibitor therapy in patients PV who history prior hydroxyurea (HU) use (including resistance or intolerance), phlebotomy requirements, palpable splenomegaly. We aimed to determine how these features contribute alone aggregate symptom burden. Patients Methods Through prospective...
The myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia and myelofibrosis, are distinguished by their debilitating symptom profiles, life-threatening complications profound impact on quality of life. role gender plays in the symptomatology neoplasms remains under-investigated. In this study we evaluated how relates to patients' characteristics, disease overall expression. A total 2,006 patients (polycythemia vera=711, thrombocythemia=830, myelofibrosis=460,...
S ummary . The biochemical defect in a patient suffering from very severe bleeding episodes was shown to be related the presence of an inhibitor which specifically interfered only with thrombin‐catalysed conversion fibrin stabilizing factor zymogen (factor XIII) into fibrinoligase, but had no effect on transamidase activity latter enzyme. As such, it differed other known inhibitors system. Inhibition could demonstrated against both human and bovine XIII. In terms neutralizing equivalents,...
Alcohol taxation is a key policy to reduce consumption and alcohol harm but evidence on tax design indicators assess are lacking. Tax two indicators: as share of lowest retail price affordability, were investigated in eight high-income nine middle-income jurisdictions. Collaborators populated the International Control (IAC) study online Policy Tool, providing measures , rates; typical prices available for take-away alcohol. These data used calculate tax/share price. Affordability was...
Abstract Background Syphilis disproportionately affects people living with HIV (PLWH). Although screening is widely done for syphilis control, there are significant delays time-to-treatment reaching 30 days in some settings Colombia. Our study aimed to model the impact of reducing on prevalence among PLWH Methods We developed a compartmental simulate transmission dynamics PLWH, considering different stages syphilis. The included and treatment pathways stratified population into high (10%)...
We have studied a young woman with multiple myeloma who became pregnant while on oral cyclophosphamide. She had normal pregnancy and was delivered by cesarean section because of fetal distress. The infant healthy at birth an “M” component in serum cord blood similar to his mother's. This abnormal protein disappeared when the evaluated 2 years age. conclude that IgG can cross placental barrier, but newborn did not any detectable disease. Chromosomal studies were normal. Cyclophosphamide...
Background By 2016, tobacco industry provided the only illicit trade estimates in Colombia and used these to discourage tax increases since 1990s. To establish viability of a threefold hike excise tax, policy makers needed unbiased cigarette. Objective estimate size cigarette five Colombian cities (63% market), analyse characteristics smokers cigarettes compare market share results with one industry-funded survey. Methods Street cross-sectional survey smokers’ self-report on consumption...
Malabsorption of folate polyglutamates prepared from yeast has been shown in eight patients with untreated tropical sprue and three out six receiving therapy for sprue. The absorptive defect among these 14 occurred more frequently all but one patient severely than folic acid.Folate polyglutamates, the principal dietary form folate, probably require deconjugation by jejunal enzyme, conjugase, before absorption. mean concentration conjugase 21 13 were both significantly less a control group....
A street cross-sectional survey in 2016 with a representative sample of 1697 smokers five Colombian cities was used to estimate the penetration illicit cigarettes (PIC). The first wave collected 3 months before 100% increase tobacco excise tax, and second data 9 after tax reform effective. OBJECTIVE : Analyse changes cigarette PIC, prices smoking behaviour patterns for (63% market). Smoking includes consumption intensity, presentation (stick/pack) place purchase. METHODS Repeated smokers'...
Several studies have shown the beneficial effects of tobacco fiscal policy, but distributional been less examined, especially at subnational level. The objective this study is to analyse a one-peso tax increase (roughly equivalent tripling current excise tax) on health, poverty, and financial outcomes level in Mexico.
Background The alcohol industry uses many of the tobacco industry’s strategies to influence policy-making, yet unlike Framework Convention on Tobacco Control, there is no intergovernmental guidance protecting policies from influence. Systematic assessment penetration and government safeguards also lacking. Here, we aimed identify nature extent in a cross-section jurisdictions. Using these data, suggested ways protect policy-makers undue Methods As part International Alcohol Control Study,...
The shift of the Noncommunicable Diseases (NCDs) epidemic, including cardiovascular disease, from developed to Low and Middle Income Countries (LMIC), creates new challenges in contexts where there is poor information on healthcare costs. Clearly this essential for planning, its relevance even more valuable as a driver prevention control NCDs. This paper begins address that handicap by estimating cost Cardiovascular Disease (Coronary Heart Stroke) Colombia, using person-based approach....
The Colombian health system has made a deep transition into managed competition since major reform in 1993. A market for insurers was created, the consumer free choice of insurer and national-level equalisation fund distributes revenues via per-capita payment. Fully subsidised insurance poor informal, comprehensive standardised benefit package contributory schemes (both covering 98 per cent population), led to low level out-of-pocket expenses high financial protection, as well reduced gaps...