Junqing Xu
A5101796264- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Hemoglobinopathies and Related Disorders
- Kruppel-like factors research
- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- COVID-19 Clinical Research Studies
- Aortic Disease and Treatment Approaches
- COVID-19 diagnosis using AI
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Trauma Management and Diagnosis
- Multiple Myeloma Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Blood Coagulation and Thrombosis Mechanisms
- Infective Endocarditis Diagnosis and Management
- Nicotinic Acetylcholine Receptors Study
- Protein Degradation and Inhibitors
- Histone Deacetylase Inhibitors Research
- Medical Imaging and Pathology Studies
- Posttraumatic Stress Disorder Research
- Thyroid and Parathyroid Surgery
- Ophthalmology and Visual Impairment Studies
- Visual perception and processing mechanisms
- Trauma and Emergency Care Studies
- Parasitic infections in humans and animals
Second Affiliated Hospital of Nanjing Medical University
2024
Shenzhen University
2019-2020
Shanghai Mental Health Center
2020
Shanghai Jiao Tong University
2020
Qingdao University
2017
Yuhuangding Hospital
2017
Air Force Medical University
2011-2016
Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2016
Institute of Hematology & Blood Diseases Hospital
2012-2016
Xijing Hospital
2011-2016
Hypertension is an essential regulator of cardiac injury and remodeling. However, the pathogenesis that contributes to hypertrophy remains be fully explored. BRD4, as a bromodomain extra-terminal (BET) family member, plays important role in critical biological processes. In study, our results showed BRD4 expression was up-regulated human mouse hypertrophied hearts, importantly these effects were modulated by reactive oxygen species (ROS) generation. angiotensin II (Ang II)-treated...
Purpose Polycythemia vera (PV) is a myeloproliferative neoplasm (MPN) associated with disabling symptoms and heightened risk of life-threatening complications. Recent studies have demonstrated the effectiveness JAK inhibitor therapy in patients PV who history prior hydroxyurea (HU) use (including resistance or intolerance), phlebotomy requirements, palpable splenomegaly. We aimed to determine how these features contribute alone aggregate symptom burden. Patients Methods Through prospective...
The myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia and myelofibrosis, are distinguished by their debilitating symptom profiles, life-threatening complications profound impact on quality of life. role gender plays in the symptomatology neoplasms remains under-investigated. In this study we evaluated how relates to patients' characteristics, disease overall expression. A total 2,006 patients (polycythemia vera=711, thrombocythemia=830, myelofibrosis=460,...
We tested 357 Chinese with primary myelofibrosis for mutations in CALR, JAK2 and MPL. CALR were detected 76 subjects (21%). There 24 (32%) type-1 (L367fs*46) 49 (64%) type-2 (K385fs*47) mutations. Seventy-two of 168 (43%) without a or MPL mutation had mutation. Subjects lower hemoglobin concentrations (P=0.001), WBC counts (P
Abstract Background Lung adenocarcinoma (LAD) is a prevalent type of bronchogenic malignant tumor and one the most critical factors related to human death. Long noncoding RNAs (lncRNAs) are involved in many complex biological processes have been emerged as extremely important regulators various cancers. LINC02418, novel lncRNA, hasn’t mentioned previous studies on cancer development. Therefore, it’s define potential function LINC02418 LAD. Methods Gene expression was examined by RT-qPCR or...
Background: Anti-angiogenesis is a promising therapeutic strategy for locally advanced breast cancer.We performed this phase II trial to evaluate the anti-angiogenesis and anti-tumor effect of rh-endostatin combined with docetaxel epirubicin in patients cancer by dynamic contrast-enhanced magnetic resonance imaging 70 previously untreated patients.Methods: The study population was randomly assigned neoadjuvant chemotherapy (neoadjuvant group) or combining chemotherapy+rh-endostatin...
An outbreak of novel coronavirus(2019-nCoV) that began in Wuhan, China, is rapidly spreading to all over and gradually multiple countries. Regarding put the epidemic prevention spread under control, early identification diagnosis play a critical role. Patients with initially no or mild symptoms Novel Coronavirus Pneumonia (2019-nCoV), namely “stealth” infection, often lack typical clinical evidence establish diagnosis. Based on analysis 4 cases stealth results this study...
To investigate the value of myeloproliferative neoplasms Symptom Assessment Form total symptom score (MPN-SAF-TSS)in assessing constitutional symptoms among Ph/BCR- ABL negative neoplasm (MPN)patients.A cohort 628 MPN patients were evaluated by MPN- SAF- TSS.Fatigue was most common (76.0%, 76.2%vs 89.9%)and highest average severity all (3.46±2.97, 3.47±2.99vs 4.74±3.04 scores)among polycythemia vera (PV), essential thrombocythemia (ET)and primary myelofibrosis (PMF)patients. Using TSS...
The purpose of this article is to investigate the clinical effect CT-guided ozone-blowing and fumigation in treatment chronic refractory cutaneous sinus ulcer. Twenty-six cases sinuses ulcers caused by different diseases were retrospectively analyzed our study. After sterilization, all patients scanned computed tomography prelocated CT treated O3-blowing fumigation. Twenty-one with traditional surgery randomly assigned into control group. A total number 15 completely cured 45 days after...
To investigate the distribution of CT features and also to introduce a novel described feature coronavirus disease-19 (COVID-19) pneumonia.A series radiologic signs in 11 COVID-19 patients were summarized made morphometric analysis.A special sign termed as "the arch bridge sign" owing its morphological mimicking an was firstly introduced. Statistical analyze showed that subpleural area is priority location (14/14) inclined perform those relatively early stage (6/8) with moderate clinical...