- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Endometrial and Cervical Cancer Treatments
- Advanced biosensing and bioanalysis techniques
- Prostate Cancer Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Biosensors and Analytical Detection
- Angiogenesis and VEGF in Cancer
- Glioma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Ovarian cancer diagnosis and treatment
- Prostate Cancer Treatment and Research
- Cancer-related molecular mechanisms research
- Electrochemical sensors and biosensors
- RNA Interference and Gene Delivery
- Renal and related cancers
- Ferroptosis and cancer prognosis
- Molecular Sensors and Ion Detection
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Renal cell carcinoma treatment
- Geochemistry and Geologic Mapping
- Advanced MRI Techniques and Applications
- Circular RNAs in diseases
- Monoclonal and Polyclonal Antibodies Research
Fujian Medical University
2015-2025
Air Force Medical University
2015-2024
Xijing Hospital
2015-2024
Maternity and Children's Hospital
2024
Simcere Pharmaceutical (China)
2023
Beijing Wuzi University
2023
Third Affiliated Hospital of Sun Yat-sen University
2018-2022
Sun Yat-sen University
2018-2022
Fujian Women and Children Hospital
2019-2022
Fuzhou Maternity and Child Health Care Hospital
2017-2022
A renewable electrochemical aptasensor was proposed for super-sensitive determination of Hg2+. The novel aptasensor, based on sulfur–nitrogen codoped ordered mesoporous carbon (SN-OMC) and thymine–Hg2+–thymine (T–Hg2+–T) mismatch structure, used ferrocene as signal molecules to achieve the conversion current signals. In absence Hg2+, thiol-modified T-rich probe 1 spontaneously formed a hairpin structure by base pairing. After being hybridized with ferrocene-labeled 2 in presence opened due...
Abstract Human papillomavirus can be contracted by sexually active women. However, only a small proportion of these infections persist and have the potential to progress into cervical cancers, indicating significant involvement immune system in cancer development. Despite this, our understanding precise contributions genes from different cell types cancers remains limited. Therefore, primary objective study was investigate causal relationships between specific development cancers. By...
Objective Gray matter loss in the limbic structures was found recent onset post traumatic stress disorder (PTSD) patients. In present study, we measured regional gray volume trauma survivors to verify hypothesis that may cause different with and without PTSD. Method High resolution T1-weighted magnetic resonance imaging (MRI) were obtained from coal mine flood disaster (n = 10) PTSD 20 no exposed normal controls. The voxel-based morphometry (VBM) method used measure three groups,...
miRNA-16 (miR16) plays an important role in modulating the drug resistance of SGC7901 cell lines to adriamycin (ADR). A variety viral carriers have been designed for miRNA delivery. However, safety concerns are currently perceived as hampering clinical application vector-based therapy. Herein a type magnetic nanoparticles (MNPs) was and synthesized using poly(ethylene glycol) (PEG)-coated Fe₃O₄ delivery system purpose reducing gastric cancer cells by enforcing miR16 expression SGC7901/ADR...
Multidrug-resistant Pseudomonas aeruginosa has become one of global threat pathogens for human health due to insensitivity antibiotics. Recently developed reprogramming metabolomics can identify biomarkers, and then, the biomarkers were used revert elevate antibiotic-mediated killing. Here, methodology was study cefoperazone/sulbactam (SCF)-resistant P. (PA-RSCF) identified reduced glycolysis pyruvate cycle, a recent clarified cycle providing respiratory energy in bacteria, as most key...
Aim/Background Ovarian Cancer (OC) accounts for the highest number of deaths among gynecological cancers. Our research is focused on investigating therapeutic potential and fundamental mechanism by which miR-142-5p exerts its effects in treatment OC. Materials Methods The GSE53829 GSE83693 data sets were collected targeted miRNA identification. RT-qPCR was conducted to evaluate expression levels miRNA, N-cadherin, ZO-1, Claudin-1, E-cadherin, DNMT1 mRNA expressions. Additionally, protein...
A variety of structural abnormalities have been described in post traumatic stress disorder (PTSD), but only a few studies focused on cortical thickness alterations recent onset PTSD. In this study, we adopted surface-based morphometry (SBM), which enables an exploration global changes throughout the brain, order to compare PTSD patients, trauma-exposed subjects without PTSD, and normal controls. Moreover, used region interest (ROI) partial correlation analysis evaluate among symptom...
To clarify diffusion and perfusion abnormalities evaluate correlation between apparent coefficient (ADC), MR histopathologic parameters of pancreatic cancer (PC).Eighteen patients with PC underwent diffusion-weighted imaging dynamic contrast-enhanced magnetic resonance (DCE-MRI). Parameters DCE-MRI ADC non-cancerous tissue were compared. Correlation the rate constant that represents transfer contrast agent from arterial blood into extravascular extracellular space (K, volume per unit (Ve),...