Yi Huan

ORCID: 0000-0002-3936-5264
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About
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Research Areas
  • MRI in cancer diagnosis
  • Radiomics and Machine Learning in Medical Imaging
  • Endometrial and Cervical Cancer Treatments
  • Advanced biosensing and bioanalysis techniques
  • Prostate Cancer Diagnosis and Treatment
  • Cervical Cancer and HPV Research
  • Biosensors and Analytical Detection
  • Angiogenesis and VEGF in Cancer
  • Glioma Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Ovarian cancer diagnosis and treatment
  • Prostate Cancer Treatment and Research
  • Cancer-related molecular mechanisms research
  • Electrochemical sensors and biosensors
  • RNA Interference and Gene Delivery
  • Renal and related cancers
  • Ferroptosis and cancer prognosis
  • Molecular Sensors and Ion Detection
  • Advanced Nanomaterials in Catalysis
  • Nanoparticle-Based Drug Delivery
  • Renal cell carcinoma treatment
  • Geochemistry and Geologic Mapping
  • Advanced MRI Techniques and Applications
  • Circular RNAs in diseases
  • Monoclonal and Polyclonal Antibodies Research

Fujian Medical University
2015-2025

Air Force Medical University
2015-2024

Xijing Hospital
2015-2024

Maternity and Children's Hospital
2024

Simcere Pharmaceutical (China)
2023

Beijing Wuzi University
2023

Third Affiliated Hospital of Sun Yat-sen University
2018-2022

Sun Yat-sen University
2018-2022

Fujian Women and Children Hospital
2019-2022

Fuzhou Maternity and Child Health Care Hospital
2017-2022

A renewable electrochemical aptasensor was proposed for super-sensitive determination of Hg2+. The novel aptasensor, based on sulfur–nitrogen codoped ordered mesoporous carbon (SN-OMC) and thymine–Hg2+–thymine (T–Hg2+–T) mismatch structure, used ferrocene as signal molecules to achieve the conversion current signals. In absence Hg2+, thiol-modified T-rich probe 1 spontaneously formed a hairpin structure by base pairing. After being hybridized with ferrocene-labeled 2 in presence opened due...

10.1021/acssensors.8b00926 article EN ACS Sensors 2018-11-09

Abstract Human papillomavirus can be contracted by sexually active women. However, only a small proportion of these infections persist and have the potential to progress into cervical cancers, indicating significant involvement immune system in cancer development. Despite this, our understanding precise contributions genes from different cell types cancers remains limited. Therefore, primary objective study was investigate causal relationships between specific development cancers. By...

10.1002/ijc.34911 article EN cc-by-nc-nd International Journal of Cancer 2024-03-06

Objective Gray matter loss in the limbic structures was found recent onset post traumatic stress disorder (PTSD) patients. In present study, we measured regional gray volume trauma survivors to verify hypothesis that may cause different with and without PTSD. Method High resolution T1-weighted magnetic resonance imaging (MRI) were obtained from coal mine flood disaster (n = 10) PTSD 20 no exposed normal controls. The voxel-based morphometry (VBM) method used measure three groups,...

10.1371/journal.pone.0048298 article EN cc-by PLoS ONE 2012-11-14

miRNA-16 (miR16) plays an important role in modulating the drug resistance of SGC7901 cell lines to adriamycin (ADR). A variety viral carriers have been designed for miRNA delivery. However, safety concerns are currently perceived as hampering clinical application vector-based therapy. Herein a type magnetic nanoparticles (MNPs) was and synthesized using poly(ethylene glycol) (PEG)-coated Fe₃O₄ delivery system purpose reducing gastric cancer cells by enforcing miR16 expression SGC7901/ADR...

10.1039/c4nr03003f article EN Nanoscale 2014-01-01

Multidrug-resistant Pseudomonas aeruginosa has become one of global threat pathogens for human health due to insensitivity antibiotics. Recently developed reprogramming metabolomics can identify biomarkers, and then, the biomarkers were used revert elevate antibiotic-mediated killing. Here, methodology was study cefoperazone/sulbactam (SCF)-resistant P. (PA-RSCF) identified reduced glycolysis pyruvate cycle, a recent clarified cycle providing respiratory energy in bacteria, as most key...

10.3389/fmicb.2021.800442 article EN cc-by Frontiers in Microbiology 2022-03-03

Aim/Background Ovarian Cancer (OC) accounts for the highest number of deaths among gynecological cancers. Our research is focused on investigating therapeutic potential and fundamental mechanism by which miR-142-5p exerts its effects in treatment OC. Materials Methods The GSE53829 GSE83693 data sets were collected targeted miRNA identification. RT-qPCR was conducted to evaluate expression levels miRNA, N-cadherin, ZO-1, Claudin-1, E-cadherin, DNMT1 mRNA expressions. Additionally, protein...

10.5530/ijper.20251283 article EN cc-by Indian Journal of Pharmaceutical Education and Research 2025-01-06

A variety of structural abnormalities have been described in post traumatic stress disorder (PTSD), but only a few studies focused on cortical thickness alterations recent onset PTSD. In this study, we adopted surface-based morphometry (SBM), which enables an exploration global changes throughout the brain, order to compare PTSD patients, trauma-exposed subjects without PTSD, and normal controls. Moreover, used region interest (ROI) partial correlation analysis evaluate among symptom...

10.1016/j.nicl.2013.08.013 article EN cc-by-nc-nd NeuroImage Clinical 2013-01-01

To clarify diffusion and perfusion abnormalities evaluate correlation between apparent coefficient (ADC), MR histopathologic parameters of pancreatic cancer (PC).Eighteen patients with PC underwent diffusion-weighted imaging dynamic contrast-enhanced magnetic resonance (DCE-MRI). Parameters DCE-MRI ADC non-cancerous tissue were compared. Correlation the rate constant that represents transfer contrast agent from arterial blood into extravascular extracellular space (K, volume per unit (Ve),...

10.1097/rct.0000000000000434 article EN Journal of Computer Assisted Tomography 2016-01-01
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