A5049092149- RNA regulation and disease
- MicroRNA in disease regulation
- Acupuncture Treatment Research Studies
- Wound Healing and Treatments
- RNA Interference and Gene Delivery
- Autophagy in Disease and Therapy
- Mesenchymal stem cell research
- Endoplasmic Reticulum Stress and Disease
- Melanoma and MAPK Pathways
- Dermatologic Treatments and Research
- Prostate Cancer Treatment and Research
- Pain Management and Placebo Effect
- Cancer, Hypoxia, and Metabolism
- Fibroblast Growth Factor Research
- Telomeres, Telomerase, and Senescence
- Vascular Malformations and Hemangiomas
- Prosthetics and Rehabilitation Robotics
- Electrospun Nanofibers in Biomedical Applications
- Facial Rejuvenation and Surgery Techniques
- Traditional Chinese Medicine Studies
- Vascular Tumors and Angiosarcomas
- Pediatric Pain Management Techniques
- Atherosclerosis and Cardiovascular Diseases
- Heterotopic Ossification and Related Conditions
- Music Therapy and Health
Air Force Medical University
2009-2024
Xijing Hospital
2010-2024
To evaluate the safety profile and efficacy of bone marrow mononuclear cells (BMMNC) transplantation for ST-segment elevation myocardial infarction (STEMI) by assessing patients their left ventricular function at up to 4 years follow-up. Eighty-six with STEMI who had successfully undergone percutaneous coronary intervention (PCI) were randomized receive intracoronary injection BMMNC (n = 41) or saline 45). Left ejection fraction, as evaluated UCG, was markedly improved 6 months (0.484 ± 0.5...
Diabetes Mellitus (DM) is widely acknowledged to increase the risk of cardiovascular death, which warrants use aggressive primary prevention strategies. The aim present study was investigate pretreatment effects tanshinone IIA (TSN), a traditional Chinese medicine, on myocardial infarct size, apoptosis, inflammation and cardiac functional recovery in diabetic rats subjected ischaemia/reperfusion (I/R).Streptozocin (STZ) induced (n = 80) were randomized receive TSN, TSN plus wortmannin [a...
Summary Electroacupuncture has been demonstrated to be effective at alleviating pain and postoperative side‐effects. Our aim was investigate whether transcutaneous electric acupoint stimulation, a low‐skill alternative needle‐based electroacupuncture, could improve the quality of recovery after ambulatory surgery. Seventy‐two women scheduled for cosmetic breast surgery were randomly allocated stimulation or sham groups. Patients in group received 30 min electrical three acupoints located on...
Abstract Background Diabetic chronic wounds are among the most common and serious complications of diabetes associated with significant morbidity mortality. Endothelial-to-mesenchymal transition (EndMT) is a specific pathological state in which endothelial cells transformed into mesenchymal response to various stimuli, such as high glucose levels oxidative stress. Acidic fibroblast growth factor (aFGF), member family, possesses strong antioxidant properties can promote differentiation stem...
A cellular metabolic network is an intricate system of biochemical routes and reactions that allow a cell to grow, survive, operate. These networks handle the conversion nutrients into energy, building blocks for structures, other bioactive compounds required functions. The network’s complex physiological function in completing catalytic could be completely comprehended from whole-body viewpoint, which considers underlying interactions between conditions body as whole, surrounding tissue,...
Abstract Excessive generation of reactive oxygen species (ROS) poses a huge obstacle to the healing process diabetic wounds, resulting in chronic, non‐healing wounds. While numerous anti‐ROS therapeutics have been developed, satisfied intra‐ and extra‐ cellular ROS homeostasis is hard be established To address this issue, nanoparticle via loading metformin CeO 2 into mesoporous silica (MSN@Met‐CeO ) designed synthesized, which then encapsulated within ROS‐responsive hydrogel shaped as...
The present study was to trace the neuronal pathway in spinal cord and brainstem following noxious stimulation acupuncture plus by using immunohistochemical technique detect expression of c-fos like protein. results showed that both group Zusanli(St.36) Lanwei(Extra 33) points a lot Fos-like immunoreactive (FLI) cell nuclei appeared structures: dorsal horn lumbar sacral (Laminae I, II, V X), n. reticularis lateralis, paragigantocellularis area A1, tractus solitarii, raphe magnus, locus...
Introduction Postburn scarring often presents a specific reconstructive challenge from both functional and cosmetic perspectives. The purpose of this study was to investigate whether autologous nanofat harvested the donor site full skin or flap can be reused for treatment early postburn scaring. Methods From July 2018 April 2022, patients with underwent scar reconstruction surgery full-thickness contour deformity and/or contracture, grafting performed during same operation. Vancouver Scar...
It is known that interferon-γ (IFN-γ) produced by activated T and NK lymphoid cells, mononuclear macrophage dendritic cells. Our previous studies have shown IFN-γ-like immunoreactivity also appears in human adrenal cortical tumour phaeochromocytoma. To investigate whether cells can produce IFN-γ, we examined 429 biopsy specimens of 30 kinds tumour-surrounding tissues glands kidneys using immunohistochemistry situ hybridisation. IFN-γ immunoactivity was 34.3% the adenomas, 50% carcinomas,...
Prostate cancer is relatively unique to man. There no naturally occurring prostate in the mouse. Pre-clinical studies involve establishment of a genetically engineered mouse model with features close those human situation. A new knock-in adenocarcinoma (KIMAP) was established, which showed close-to-human kinetics tumor development. In order determine if similar associated heterogeneous architecture situation, we utilized histological grading system (Gleason analogous system) Gleason and flow...
Objective This study was designed to evaluate the contribution of apelin therapeutic efficacy mesenchymal stem cells in hindlimb ischaemia mice. Methods Mesenchymal (MSC) expressing firefly luciferase (Fluc) were isolated from ß-actin-luc mice and characterised by flow cytometry bioluminescence imaging (BLI). Male FVB underwent femoral artery ligation received MSC (1×106) or with Apelin intra-quadriceps femoris muscle injection. Cell survival imaged BLI. Angiogenesis assessed...