A5100625881- Autophagy in Disease and Therapy
- Traumatic Brain Injury and Neurovascular Disturbances
- Berberine and alkaloids research
- Hemodynamic Monitoring and Therapy
- Neurological disorders and treatments
- Optical Imaging and Spectroscopy Techniques
- Gout, Hyperuricemia, Uric Acid
- Inflammatory mediators and NSAID effects
- Pharmacological Effects of Natural Compounds
- Botulinum Toxin and Related Neurological Disorders
- Herpesvirus Infections and Treatments
- Inflammasome and immune disorders
- Ocular Disorders and Treatments
- Marine Biology and Environmental Chemistry
- Blood transfusion and management
- Freezing and Crystallization Processes
- Connexins and lens biology
- Rheumatoid Arthritis Research and Therapies
- Viral Infections and Outbreaks Research
- Bioinformatics and Genomic Networks
- Glioma Diagnosis and Treatment
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Melanoma and MAPK Pathways
- Cardiovascular Health and Disease Prevention
Shanghai Jiao Tong University
2024
China Southern Power Grid (China)
2024
Nanjing Medical University
2024
Fujian Medical University
2024
Beijing Tian Tan Hospital
2014-2023
Capital Medical University
2014-2023
Nanjing University of Chinese Medicine
2011-2023
Bengbu Medical College
2019-2023
South China Agricultural University
2021
Graybug Vision (United States)
2017-2018
Background Limited research has been conducted to quantitatively assess the impact of systemic inflammation in metabolic dysfunction-associated fatty liver disease (MAFLD) and sub-clinical carotid atherosclerosis (SCAS). The immune-inflammation index (SII), which integrates inflammatory cells, emerged as a reliable measure local immune response Therefore, this study aims mediating role SII association between MAFLD SCAS type 2 diabetes mellitus (T2DM). Method This prospectively recruited 830...
The antiinflammatory effects of the copper-aspirin complex (Cu-Asp) were more potent than that Asp in rats or mice with fewer classic adverse effects. aim this study was to determine cause by evaluating Cu-Asp selective inhibition on cyclooxygenases (COX). COX-1 evaluated based 6-keto-prostaglandin F1α (6-keto-PGF1α) an endothelial cell model, and COX-2 prostaglandin E2 (PGE2) a macrophage model. Radioimmunoassay (RIA) applied 6-keto-PGF1α resting human umbilical vein line (ECV304), PGE2...
Abstract Avian leukosis virus subgroup J (ALV-J) causes oncogenic disease in chickens China, resulting great harm to poultry production, and remains widespread China. Herein, we employed a cross-priming amplification (CPA) approach nucleic acid detection device establish visual rapid method for ALV-J. The sensitivity of CPA, polymerase chain reaction (PCR) real-time PCR (RT-PCR) was compared, the three methods were used detect ALV-J cell cultures which inoculated with clinical plasma. result...
Abstract Background Co-infections of Apple chlorotic leaf spot virus (ACLSV) and Cherry green ring mottle (CGRMV) in peach is common China have resulted significant yield reductions. A reliable, sensitive quantitive method needed to detect distinguish between ACLSV CGRMV peach. Findings We developed a specific SYBR Green-I based RT-qPCR for the quantification different tissues, duplex system simultaneously. The was optimized using standard samples transcribed by T7 Large Scale RNA Production...
Cyclooxygenase 2 (COX-2) pathway inhibitors were regarded as promising nonsteroidal antiinflammatory drugs (NSAIDs). We discovered that the COX-2 in A549 cells, a human lung cancer cell line, was activated by serum-free stimulation, and drug screening model for NSAIDs established based on this principle with simple performance sufficient reliability. The treating medium 12 h. cells incubated NS398 (selective inhibitor), SC560 COX-1 acetyl salicylic acid (ASA) (nonselective COX inhibitor) at...
Small-molecular-weight collagen peptides (CPs) with high zinc-chelating ability were extracted from pufferfish skin. Chelation of CPs zinc was performed to prepare novel CP-chelated (CP-Zn) nanoparticles. CP-Zn nanoparticles spherical, regular, and well dispersed an average size ∼100 nm. The zeta potential assay used explore the stability much more stable in pH range 3–8. structural properties characterized by matrix-assisted laser desorption–ionization time-of-flight mass spectrometry,...
Introduction: This study aimed to elucidate the role and molecular mechanisms of acidic leucine-rich nuclear phosphoprotein 32 kDa B (Anp32b) deficiency in ocular development. Methods: We used constitutive C57BL/6-derived Anp32b−/− mice Anp32b development, including phenotype proportion eye malformation different genotypes. RNA-seq analysis rescue experiments were performed investigate underlying Anp32b. Results: Deletion contributes severe defects anophthalmia microphthalmia. Moreover, is...
Objective To investigate the effects of propofol and sevoflurane on neurological recovery traumatic brain injury (TBI) patients in early postoperative stage.Methods We retrospectively analyzed clinical data TBI who underwent craniotomy or decompressive craniectomy. Generalized additive mixed model (GAMM) was used to analyze Glasgow Coma Scale (GCS) days 1, 3, 7. Multivariate regression analysis two anesthetics Outcome (GOS) at discharge.Results A total 340 were enrolled this study. There 110...