Mei Tu

ORCID: 0000-0003-4241-7886
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Research Areas
  • Nutrition and Health in Aging
  • Bone health and osteoporosis research
  • Liver Disease Diagnosis and Treatment
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cancer, Lipids, and Metabolism
  • Cardiovascular Disease and Adiposity
  • Cardiovascular Health and Disease Prevention
  • Cardiac Valve Diseases and Treatments
  • Gastric Cancer Management and Outcomes
  • Synthesis of Organic Compounds
  • Bone Metabolism and Diseases
  • Acute Myocardial Infarction Research
  • Dialysis and Renal Disease Management
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiovascular Function and Risk Factors
  • Body Composition Measurement Techniques
  • Chronic Kidney Disease and Diabetes
  • Natural Antidiabetic Agents Studies
  • Phytochemicals and Antioxidant Activities
  • Cerebrospinal fluid and hydrocephalus
  • Folate and B Vitamins Research
  • Bariatric Surgery and Outcomes
  • Parathyroid Disorders and Treatments
  • Helicobacter pylori-related gastroenterology studies
  • Lipoproteins and Cardiovascular Health

Fujian Medical University
2018-2024

First Affiliated Hospital of Fujian Medical University
2018-2024

National Health and Family Planning Commission
2018

Creative Commons
2018

Sichuan University
2016

Objective: Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and dipeptidyl peptidase-4 inhibitors (DPP-4i) profoundly affect the gastrointestinal motor system, which may increase incidence of inadequate bowel cleaning symptoms. Hence, this observational study mainly aimed to assess influence GLP-1 RAs liraglutide DPP-4i sitagliptin on preparation in type 2 diabetes (T2DM). Method: This consecutively enrolled T2DM scheduled for a colonoscopy. Participants were prospectively separated...

10.3389/fphar.2023.1176206 article EN cc-by Frontiers in Pharmacology 2023-04-06

Background Limited research has been conducted to quantitatively assess the impact of systemic inflammation in metabolic dysfunction-associated fatty liver disease (MAFLD) and sub-clinical carotid atherosclerosis (SCAS). The immune-inflammation index (SII), which integrates inflammatory cells, emerged as a reliable measure local immune response Therefore, this study aims mediating role SII association between MAFLD SCAS type 2 diabetes mellitus (T2DM). Method This prospectively recruited 830...

10.3389/fendo.2024.1406793 article EN cc-by Frontiers in Endocrinology 2024-06-18

Abstract Background Adropin, a newly‑identified energy homeostasis protein, has been implicated in the maintenance of metabolic and insulin sensitivity. This study attempts to measure association between serum adropin carotid atherosclerosis patients with type 2 diabetes mellitus (T2DM). Methods cross‑sectional was performed 503 hospitalized T2DM.Serum level measured by sandwich enzyme-linked immunosorbent assay. The assessed color Doppler sonography. atherosclerotic plaque tested logistic...

10.1186/s13098-022-00796-y article EN cc-by Diabetology & Metabolic Syndrome 2022-02-08

The relationship between obesity and diabetic retinopathy (DR) remains controversial, the sarcopenic DR is still unclear. purpose of this study to investigate obesity, in patients with type 2 diabetes mellitus (T2DM).

10.1186/s12986-024-00842-8 article EN cc-by-nc-nd Nutrition & Metabolism 2024-08-19

This study aims to examine the clinical significance of ultrasound evaluation gastrocnemius muscle (GM) in identifying sarcopenia patients with type 2 diabetes (T2D).One hundred and fifty-three T2D were included this study. We measured appendicular skeletal mass index (ASMI), handgrip strength, 6-meter walking speed. The US-derived thickness (MT), cross-sectional area (CSA), shear wave elastography (SWE) GM also measured. assessed correlations between indicators US features. model for...

10.2147/dmso.s435517 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2023-10-01

The relationship between malnutrition and diabetic retinopathy (DR) is still unclear. purpose of this study to investigate the DR in type 2 patients.A cross-sectional was conducted on 612 patients with diabetes mellitus. Four assessment tools: Global Leadership Initiative Malnutrition (GLIM) criteria, controlling nutritional status (CONUT), risk index (NRI), prognostic (PNI), were applied assess population. association examined using multivariable logistic regression ordered regression.The...

10.1155/2023/1613727 article EN cc-by Journal of Diabetes Research 2023-11-17

Objective: Emerging evidences demonstrated that chronic inflammation can influence bone metabolism in type 2 diabetes mellitus (T2DM), leading to homeostasis imbalance. The aim of this study was assess the correlations between novel pro-inflammatory indexes like monocyte high-density lipoprotein (MHR), apolipoprotein A1 (MAR) ratios and mineral density (BMD), turnover markers Chinese postmenopausal women with T2DM. Method: In study, a total 619 participants complete data were included final...

10.3389/fphar.2022.1062999 article EN cc-by Frontiers in Pharmacology 2022-11-07

Background. Legumain is related to carotid atherosclerotic plaques and may be a new biomarker of atherosclerosis. However, the association between legumain peripheral artery disease (PAD) lower extremity has been less studied. This study aimed at exploring potential link PAD in patients with type 2 diabetes mellitus (T2DM). Methods. A cross-sectional was conducted on 483 hospitalized T2DM patients. The serum level measured by sandwich enzyme-linked immunosorbent assay. evaluated color...

10.1155/2021/5651469 article EN cc-by Journal of Diabetes Research 2021-12-18

We investigated the relationship between serum osteoinductive factor (OIF) and diabetic nephropathy (DN), its potential use as a diagnostic marker for DN. This study included 177 patients with type 2 diabetes mellitus (T2DM) normoalbuminuria, 42 DN microalbuminuria, 49 macroalbuminuria, well 296 controls. Baseline characteristics, microalbuminuria prevalence, macroalbuminuria complications were compared OIF quartiles. Serum was examined by enzyme-linked immunosorbent assay. Other clinical...

10.1097/md.0000000000011759 article EN cc-by-nc Medicine 2018-08-01

BACKGROUND Anti-vascular endothelial growth factor (anti-VEGF) therapy is critical for managing neovascular age-related macular degeneration (nAMD), but understanding factors influencing treatment efficacy essential optimizing patient outcomes. AIM To identify the risk affecting anti-VEGF in nAMD and develop a predictive model short-term response. METHODS In this study, 65 eyes of exudative AMD patients after ≥ 1 mo were observed using optical coherence tomography angiography. Patients...

10.4329/wjr.v16.i9.418 article EN World Journal of Radiology 2024-09-26

The association between lipoprotein(a) (Lp(a)) and sarcopenia in T2DM patients of general age is unclear, whether this differs by sex remains uncertain. We intend to analyze the Lp(a) with type 2 diabetes mellitus (T2DM) sex. December 2021 2022 were consecutively enrolled. Sarcopenia was defined according criteria Consensus Asian Working Group for (AWGS) 2019.A multivariable logistic regression model used calculate odds ratio Lp(a)≥30 mg/dL total all sexes. Restricted cubic splines also...

10.2147/dmso.s489605 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2024-11-01

Emerging evidence demonstrated that perirenal fat may modulate bone metabolism through several pathological pathways. This study was aimed to assess the associations between thickness (PrFT) and turnover markers (BTMs) mineral density (BMD) in postmenopausal women with type 2 diabetes mellitus (T2DM) further explore correlation PrFT osteoporosis.In this cross-sectional study, a total of 626 participants complete data were enrolled study. Demographic anthropometric information collected....

10.3389/fendo.2022.990667 article EN cc-by Frontiers in Endocrinology 2022-10-25

According to urinary albumin excretion rates(UAER), 256 patients with type 2 diabete mellitus(T2DM)were divided into normal albuminuria(NA), microalbuminuria(MA), and clinical nephropathy(CN)groups while 108 healthy subjects as control group. The analysis of variance single factor was applied examine lipoprotein(a), triglyceride, total cholesterol(TC), low-density lipoprotein cholesterol(LDL-C), cystatin C, homocysteine. correlations lipoprotein(a)with rate(UAER)and glomerular filtration...

10.3760/cma.j.issn.1000-6699.2016.01.013 article EN Zhonghua neifenmi daixie zazhi 2016-01-25
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