- Legume Nitrogen Fixing Symbiosis
- Plant nutrient uptake and metabolism
- Nematode management and characterization studies
- Plant and Fungal Interactions Research
- Plant Virus Research Studies
- Agronomic Practices and Intercropping Systems
- Plant Pathogens and Fungal Diseases
- Plant-Microbe Interactions and Immunity
- Bacteriophages and microbial interactions
- Plant Disease Resistance and Genetics
- Inflammasome and immune disorders
- Plant Physiology and Cultivation Studies
- Phytochemistry and Biological Activities
- Extracellular vesicles in disease
- Plant Toxicity and Pharmacological Properties
- Drug-Induced Hepatotoxicity and Protection
- Insect-Plant Interactions and Control
- Dietary Effects on Health
- Diet and metabolism studies
- Thermoregulation and physiological responses
- MicroRNA in disease regulation
- Coastal wetland ecosystem dynamics
- Polysaccharides and Plant Cell Walls
- Fungal Plant Pathogen Control
- Plant Micronutrient Interactions and Effects
China Agricultural University
2014-2024
Shaanxi University of Chinese Medicine
2024
Xi’an Children’s Hospital
2019-2024
Xi'an Jiaotong University
2024
University of Freiburg
2017-2023
State Key Laboratory of Plant Physiology and Biochemistry
2023
Chinese Academy of Agricultural Sciences
2013-2015
Institute of Plant Protection
2013-2015
State Key Laboratory of Biology of Plant Diseases and Insect Pests
2013
Significance Pattern recognition receptors control the cellular entry of pathogenic as well symbiotic microbes. While ligand-induced changes in receptor mobility at plasma membrane and their localization nanodomains are general features, molecular mechanism biological relevance this phenomenon have remained unknown. Here we show that immobilization cell LYK3 requires presence actin two scaffold proteins, FLOT4 SYMREM1. forms initial core structure, infection-induced expression subsequent...
The root nodule symbiosis with its global impact on nitrogen fertilization of soils is characterized by an intracellular colonization legume roots rhizobia. Although the symbionts are initially taken up morphologically adapted hairs, rhizobia persistently progress within a membrane-confined infection thread through several cortical and later nodular cell layers. Throughout this transcellular passaging, have to repeatedly pass host plasma membranes walls. Here, we investigated essential...
In plants, the topological organization of membranes has mainly been attributed to cell wall and cytoskeleton. Additionally, few proteins, such as plant-specific remorins have shown function protein lipid organizers. Root nodule symbiosis requires continuous membrane re-arrangements, with bacteria being finally released from infection threads into membrane-confined symbiosomes. We found that mutations in symbiosis-specific SYMREM1 gene result highly disorganized perimicrobial membranes....
A novel circular DNA virus sequence has been identified through next-generation sequencing and in silico assembly of small RNAs 21–24 nt from an apple tree grown China. The genome was cloned using two independent approaches sequenced. With a size 2932 nt, it showed the same genomic structure conserved origin replication reported for members family Geminiviridae. However, low nucleotide amino acid identity with known geminiviruses indicated that virus, which provisional name geminivirus (AGV)...
Legumes have maintained the ability to associate with rhizobia sustain nitrogen-fixing root nodule symbiosis (RNS). In Medicago truncatula, Nod factor (NF)-dependent intracellular colonization by Sinorhizobium meliloti initiates from young, growing hairs. They form rhizobial traps physically curling around symbiont.1Brewin N.J. Plant cell wall remodelling in rhizobium-legume symbiosis.Crit. Rev. Sci. 2004; 23: 293-316Crossref Scopus (207) Google Scholar,2Gage D.J. Infection and invasion of...
Abstract Abnormal immune response contributes to pathophysiology of pneumonia and is recognized as a main factor for high incidence rate in children. The association between exosomes inflammation has been reported diverse cell types diseases. current study focuses on exploring the effects exosomal miR‐103a‐3p lipopolysaccharide (LPS)‐induced inflammation, investigates underlying mechanisms. We proved that was lowly expressed blood samples patients LPS‐induced lung cells, overexpression...
Abstract Background Co-infections of Apple chlorotic leaf spot virus (ACLSV) and Cherry green ring mottle (CGRMV) in peach is common China have resulted significant yield reductions. A reliable, sensitive quantitive method needed to detect distinguish between ACLSV CGRMV peach. Findings We developed a specific SYBR Green-I based RT-qPCR for the quantification different tissues, duplex system simultaneously. The was optimized using standard samples transcribed by T7 Large Scale RNA Production...
Pediatric febrile illnesses are relatively common in clinical practice, especially respiratory and digestive system diseases most common, which can be said to frequent. Whether the acute or recovery period, improper dietary feeding protective measures occur from time time, easily lead recurrence, delay, aggravation other diseases, how prevent pediatric problems this area needs solved. Based on theory of diet recurrence heat that has not yet dissipated, it is important discuss role influence...
Abstract Organization of membrane topologies in plants has so far been mainly attributed to the cell wall and cytoskeleton. Taking rhizobial infections legume root cells, where plasma membranes undergo dynamic large-scale topology changes, as an initial model, we challenged this paradigm tested whether additional scaffolds such plant-specific remorins that accumulate on highly curved often wall-less domains, control local dynamics. Indeed, loss-of-function mutants remorin protein SYMREM1...
Abstract The root nodule symbiosis with its global impact on nitrogen fertilization of soils is characterized by an intracellular colonization legume roots rhizo-bacteria. While the symbionts are initially taken up morphologically adapted hairs, rhizobia persistently progress within a membrane-confined infection thread through several cortical and later nodular cell layers. Throughout this transcellular passaging, have to repeatedly pass host plasma membranes walls. Here, we genetically...
ABSTRACT Plant cell infection is tightly controlled by surface receptor-like kinases (RLKs) Alike other RLKs the Medicago truncatula entry receptor LYK3 laterally segregates into membrane nanodomains in a stimulus-dependent manner. Although nanodomain localization arises as generic feature of plant proteins, molecular mechanisms underlying such dynamic transitions and their functional relevance remained poorly understood. Here, we demonstrate that actin flotillin protein FLOT4 form primary...
ABSTRACT Plant cell infections are tightly orchestrated by wall (CW) alterations, plasma membrane (PM) resident signalling processes and dynamic remodelling of the cytoskeleton. During root nodule symbiosis these result in morpho-dynamic responses including hair swelling curling, PM invagination polar growth a tubular infection structure, thread (IT). However, molecular details driving guiding events remain to be unravelled. Here, we studied formin protein (SYFO1) M. truncatula that is...