A5074386457- Luminescence Properties of Advanced Materials
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Lanthanide and Transition Metal Complexes
- Perovskite Materials and Applications
- Nanoplatforms for cancer theranostics
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Inorganic Fluorides and Related Compounds
- Radiation Detection and Scintillator Technologies
- Magnetism in coordination complexes
- Advanced Photocatalysis Techniques
- Metal-Organic Frameworks: Synthesis and Applications
- Angiogenesis and VEGF in Cancer
- Luminescence and Fluorescent Materials
- Electrochemical sensors and biosensors
- Cell Adhesion Molecules Research
- Neuroscience and Neuropharmacology Research
- Quantum Dots Synthesis And Properties
- Gas Sensing Nanomaterials and Sensors
- Signaling Pathways in Disease
- Catalytic Processes in Materials Science
- Polyoxometalates: Synthesis and Applications
- Mesoporous Materials and Catalysis
- Photoacoustic and Ultrasonic Imaging
Chinese Academy of Sciences
2016-2025
Changchun Institute of Applied Chemistry
2016-2025
University of Science and Technology of China
2014-2025
Southeast University
2019-2025
Shanxi Agricultural University
2025
Institute of Biophysics
2014-2024
North University of China
2023-2024
Beijing Luhe Hospital Affiliated to Capital Medical University
2022-2024
Qufu Normal University
2022-2024
Shijiazhuang University
2024
Significance Nanoparticles capable of specifically binding to target cells and delivering high doses therapeutic drugs with optimized safety profiles are much sought after in the nanomedical field. Here, we developed a natural H-ferritin (HFn) nanocarrier that delivered concentration drug doxorubicin (Dox) tumor significantly inhibited growth single-dose treatment while also showing excellent biocompatibility murine cancer models. Compared clinically approved liposomal Dox (Doxil), HFn-Dox...
Rapid and sensitive detection methods are in urgent demand for the screening of extensively used organophosphorus pesticides highly toxic nerve agents their neurotoxicity. In this study, we developed a novel Fe(3)O(4) magnetic nanoparticle (MNP) peroxidase mimetic-based colorimetric method rapid agents. The assay is composed MNPs, acetylcholinesterase (AChE), choline oxidase (CHO). enzymes AChE CHO catalyze formation H(2)O(2) presence acetylcholine, which then activates MNPs to oxidation...
A series of lanthanide metal‐organic frameworks (Ln‐MOFs) are synthesized through solvothermal conditions with 1,3‐bis(4‐carboxyphenyl)imidazolium (H 2 L). Owing to the contraction effect, two different types Ln‐MOFs, namely, {[Ln(L) (OH)]·3H O} n (Ln:Pr, Nd, Sm) and (COO)(H O) ]·H (Ln: Eu, Gd, Tb, Dy, Tm, Yb, Y), their corresponding codoped Ln‐MOFs Eu x Tb 1‐ L obtained. With careful adjustment relative concentration ions excitation wavelength, color luminescence can be systematically...
Metal-organic frameworks (MOFs), which are typically embedded in polymer matrices as composites, emerging a new class of carriers for sustained drug delivery. Most the MOFs and polymers used so far these however, not pharmaceutically acceptable. In investigation reported herein, composites γ-cyclodextrin (γ-CD)-based (CD-MOFs) polyacrylic acid (PAA) were prepared by solid oil-in-oil (s/o/o) emulsifying solvent evaporation method. A modified hydrothermal protocol has been established produces...
To elaborately fabricate real‐time monitoring and therapeutic function into a biocompatible nanoplatform is promising route in the cancer therapy field. However, package of diagnosis treatment single‐“element” nanoparticle remains challenge. Herein, ultrasmall poly(vinylpyrrolidone)‐protected bismuth nanodots (PVP‐Bi nanodots) are successfully synthesized through an ultrafacile strategy (1 min only under ambient conditions). The easy to synthesize both laboratory large scale using low‐cost...
The effective activation and utilization of metakaolin as an alkali activated geopolymer precursor its use in concrete surface protection is great interest. In this paper, the formula metakaolin-based geopolymers was studied using orthogonal experimental design. It found that optimal prepared with metakaolin, sodium hydroxide, silicate water, molar ratio SiO2:Al2O3:Na2O:NaOH:H2O being 3.4:1.1:0.5:1.0:11.8. X-ray diffraction (XRD) Fourier transform infrared spectroscopy (FT-IR) were adopted...
In this article we synthesized a series of phosphors K2MgGeO4:Bi3+ with high brightness for white light-emitting diodes (WLEDs) conversion and investigated their crystal structures luminescence properties using powder X-ray diffraction, diffuse reflectance spectra, photoelectron spectroscopy, photoluminescence absolute quantum efficiency. phosphor exhibits intense absorption in near-UV area presents broad asymmetric emission band the main peak located at 614 nm, which was ascribed to 3P1 →...
The complexity, diversity, and heterogeneity of malignant tumors pose a formidable challenge for antitumor therapy. To achieve the goal significantly enhancing effect, nanomedicine-based synergistic therapy is one important strategies. Herein, we innovatively report defect-rich glassy IrTe2 (G-IrTe2) with weak Ir–Te bond strength sonodynamic (SDT), chemodynamic (CDT), mild photothermal (PTT). G-IrTe2 sonosensitizer under ultrasound (US) stimuli exhibits excellent reactive oxygen species...
The epithelial-mesenchymal transition (EMT) plays an important role in breast cancer metastasis, especially the most aggressive and lethal subtype, “triple-negative cancer” (TNBC). Here, we report that CD146 is a unique activator of EMTs significantly correlates with TNBC. In epithelial cells, overexpression down-regulated markers up-regulated mesenchymal markers, promoted cell migration invasion, induced stem cell-like properties. We further found RhoA pathways positively regulated...
Nanoscale Tb-active coordination polymers Tb(BTC)(H2O)6 were facilely, rapidly and environmentally-friendly fabricated at room temperature. The structures of the samples confirmed by powder X-ray diffraction elemental analyses, morphologies characterized SEM. studies photoluminescence properties reveal that these nanostructured exhibit green emission, corresponding to 5D4 → 7FJ transitions Tb3+ ions under UV light excitation, which represents highly selective sensitive sensing for metal...
Mercury(II) ions have emerged as a widespread environmental hazard in recent decades. Despite different kinds of detection methods reported to sense Hg(2+) , it still remains challenging task develop new sensing molecules replenish the fluorescence-based apparatus for detection. This communication demonstrates novel fluorescent sensor using UiO-66-NH2 and T-rich FAM-labeled ssDNA hybrid system detect sensitively selectively. To best our knowledge, has rarely been that MOF is utilized...
Significance Development of the blood–brain barrier (BBB) requires spatiotemporal coordination cerebrovascular endothelial cells (ECs) and pericytes. Until now, molecular mechanism(s) coordinating pericyte–EC behaviors during this process have been incompletely understood. In study, combining analysis EC-/pericyte-specific Cd146 -KO mice in vitro BBB models, we report CD146 as a dynamic coordinator regulating communication between ECs pericytes within neurovascular unit development. Our...
Upconversion (UC) nanoparticles (UCNPs) have evoked considerable attention in many fields owing to their fascinating features. However, rigorous synthesis conditions and expensive raw materials often limit further applications. Here, a novel hexagonal phase NaBiF 4 UC matrix through very facile method (one min only at room temperature) is synthesized. The show good monodispersity with uniform size. Under the 980 nm irradiation, Yb 3+ /Ln (Ln = Er, Ho, Tm) codoped excellent luminescence...
The persistence of cholesterol-engorged macrophages (foam cells) in the artery wall fuels development atherosclerosis. However, mechanism that regulates formation macrophage foam cells and impedes their emigration out inflamed plaques is still elusive. Here, we report adhesion receptor CD146 controls retention within plaque during atherosclerosis exacerbation. expressed on human mouse atheroma can be upregulated by oxidized low-density lipoprotein (oxLDL). triggers activation driving...