- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Corneal Surgery and Treatments
- Ophthalmology and Visual Impairment Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- MRI in cancer diagnosis
- Ocular Surface and Contact Lens
- Monoclonal and Polyclonal Antibodies Research
- Intraocular Surgery and Lenses
- Radiopharmaceutical Chemistry and Applications
- Advanced Neuroimaging Techniques and Applications
- Advanced Biosensing Techniques and Applications
- Plasma Applications and Diagnostics
- Radiation Dose and Imaging
- Ophthalmology and Eye Disorders
- Ultrasound and Hyperthermia Applications
- Boron Compounds in Chemistry
- Medical Imaging and Analysis
- Medical Imaging Techniques and Applications
- Ultrasound Imaging and Elastography
- Gastric Cancer Management and Outcomes
- Radiation Therapy and Dosimetry
- Effects of Radiation Exposure
Wenzhou Medical University
2017-2025
Affiliated Eye Hospital of Wenzhou Medical College
2017-2025
Zhejiang Lab
2025
Mianyang Third People's Hospital
2025
Zhejiang Chinese Medical University
2025
Nanjing Medical University
2022-2024
Beijing Hospital
2022-2024
National Clinical Research Center for Digestive Diseases
2024
State Key Laboratory of Ophthalmology
2024
Harbin Institute of Technology
2024
Purpose: The objective of this study is to evaluate the in vivo corneal biomechanical response three laser refractive surgeries. Methods: Two hundred and twenty-seven patients who submitted transepithelial photorefractive keratectomy (tPRK), femtosecond laser-assisted in-situ keratomileusis (FS-LASIK), or small-incision lenticule extraction (SMILE) were included study. All cases examined with Corvis ST preoperatively (up 3 months) postoperatively at 1, 3, 6 months, differences main device...
To assess the diurnal changes in corneal biomechanics healthy young adults. At Wenzhou Medical University Eye Hospital China, a prospective case series. Each subject had six Corvis ST examinations, from 10:00 on first day to 6:00 following day, at 4-hour intervals. The data collected included biomechanically corrected IOP (bIOP), central thickness (CCT) and dynamic response (DCR) parameters, namely deformation amplitude (DA), ratio between DA values apex 2 mm (DAR2), integrated inverse...
Recently bismuth-based nanoparticles have drawn extensive attention as radiosensitizer in radiotherapy due to high atomic number, low toxicity, and cost. This study aims introduce the applicability of bismuth ferrite (BFO, BiFeO3) a new multifunctional theranostic agent for radiotherapy, magnetic resonance imaging (MRI), computed tomography (CT) well hyperthermia mediator. After evaluation BFO biocompatibility which were synthesized by conventional sol-gel method, we investigated dose...
The study of corneal biomechanics in vivo has been evolving fast recent years. While an organised structure is necessary for its transparency, resistance to occasional external insults and bearing the intraocular pressure (IOP), which several clinically relevant events can disturb. This review focuses on three techniques that are available clinical use, namely Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA), Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany)...
To evaluate the effectiveness of methods to correct intraocular pressure (IOP) measurements obtained using Goldmann applanation tonometer (GAT), ocular response analyzer (ORA), and Corvis ST (CVS) for effects corneal stiffness parameters: central thickness (CCT), curvature (R), age in a Chinese population.Data were collected 99 eyes participants. Whereas cornea-corrected IOP was directly from ORA (ORA-IOPcc), cornea correction GAT CVS implemented multiparameter equations developed earlier....
To investigate corneal epithelial thickness changes during a 6-month follow-up period after transepithelial photorefractive keratectomy (tPRK), femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE).This prospective study included 76 eyes of participants who underwent myopic refractive surgery (23 FS-LASIK, 22 SMILE, 31 tPRK). Epithelial anterior curvature were averaged over 4 regions (subdivided into 25 areas) measured by...
Purpose: To test the performance of four tonometers in providing IOP measurements that were free effects corneal biomechanics changes caused by refractive surgery.Methods: Four employed to provide for 65 participants who accepted Femtosecond laser-assisted LASIK (FS-LASIK). The included GAT-IOP Goldmann Applanation Tonometer, DCT-IOP Dynamic Contour Goldmann-correlated (ORA-IOPg) and corneal-compensated (ORA-IOPcc) Ocular Response Analyzer, uncorrected (CVS-IOP) biomechanically corrected...
To test the performance of 4 tonometers in estimating intraocular pressure (IOP) after 3 forms refractive surgery.Eye Hospital, Wenzhou Medical University, China.Prospective case series.Patients matched for preoperative age, corneal thickness, and myopic correction enrolled femtosecond laser-assisted laser situ keratomileusis (FS-LASIK), small-incision lenticule extraction (SMILE), or transepithelial photorefractive keratectomy (tPRK) were included study. For each patient, measurements IOP...
Subarachnoid hemorrhage (SAH) denotes a serious type of hemorrhagic stroke that often leads to poor prognosis and poses significant socioeconomic burden. Timely assessment the SAH patients is paramount clinical importance for medical decision making. Currently, evaluation heavily relies on patients’ information, which suffers from limited accuracy. Non-contrast computed tomography (NCCT) primary diagnostic tool SAH. Radiomics, an emerging technology, involves extracting quantitative...
To evaluate the regional effects of different corneal cross-linking (CXL) protocols on biomechanical properties.The study involved both eyes 50 rabbits, and left were randomized to five intervention groups, which included standard CXL group (SCXL), was exposed 3-mW/cm2 irradiation, three accelerated groups (ACXL1-3), ultraviolet-A at irradiations 9 mW/cm2, 18 30 respectively, but with same total dose (5.4 J/cm2). A control (CO) not ultraviolet-A. No surgery done contralateral eyes. The...
Purpose To assess the regional changes in corneal shape after femtosecond laser–assisted laser situ keratomileusis (FS-LASIK) patients with different myopia extents. Setting Eye Hospital, Wenzhou Medical University, Wenzhou, China. Design Retrospective case series. Methods A retrospective study of myopic eyes treated FS-LASIK was conducted to within regions surgery. Corneal curvature measured central region (0 mm 3.0 diameter), pericentral (3.0 6.0 diameter) and peripheral (6.0 9.0...
This study evaluated the outcomes of laser in situ keratomileusis (LASIK) combined with prophylactic corneal collagen cross-linking (CXL) correcting myopia cases increased estimated risk postoperative ectasia, detected by regional analysis morphology.The retrospective included 180 eyes 99 patients. Group 1 (94 49 patients) as "Ectasia Risk Factor Score System for LASIK", underwent femtosecond laser-assisted LASIK (FS-LASIK) CXL, using short riboflavin soaking time and low UV energy. 2 (86 50...
To investigate changes in corneal curvature different zones of the posterior surface during a 6-month follow-up period after transepithelial photorefractive keratectomy (tPRK), femtosecond laser-assisted excimer laser situ keratomileusis (FS-LASIK), and small incision lenticule extraction (SMILE).The study included total 202 eyes, including 65, 77, 60 that underwent tPRK, FS-LASIK, SMILE, respectively. Elevation data for were obtained preoperatively (pre), as well 1 week (pos1w), month...