- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Optical Coherence Tomography Applications
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Ophthalmology and Eye Disorders
- Optical measurement and interference techniques
- Ocular Infections and Treatments
- Ocular Disorders and Treatments
- Cardiovascular and Diving-Related Complications
- Infant Development and Preterm Care
- Ergonomics and Musculoskeletal Disorders
- Asphalt Pavement Performance Evaluation
- Ocular Diseases and Behçet’s Syndrome
- Veterinary Equine Medical Research
- Liver physiology and pathology
- Infrastructure Maintenance and Monitoring
- Visual perception and processing mechanisms
- Allergic Rhinitis and Sensitization
- Imbalanced Data Classification Techniques
- Retinal and Macular Surgery
Wenzhou Medical University
2016-2025
Affiliated Eye Hospital of Wenzhou Medical College
2016-2025
State Key Laboratory of Ophthalmology
2024
National Clinical Research Center for Digestive Diseases
2024
He Eye Hospital
2023
Ministry of Education of the People's Republic of China
2015-2019
University of Liverpool
2018
National Natural Science Foundation of China
2014-2016
Ministero della Salute
2016
Fondazione G.B. Bietti
2016
<h3>Objective</h3> To evaluate the precision of measurements in healthy subjects obtained with a new optical biometer (OA-2000, Tomey, Nagoya, Japan) using swept-source coherence tomography (SS-OCT) and compare these those provided by IOLMaster v5.4 (Carl Zeiss Meditec AG, Jena, Germany) partial interferometry (PCI). <h3>Methods</h3> Axial length (AL), keratometry (K) over 2.5 mm 3.0 diameters, anterior chamber depth (ACD) (corneal epithelium to lens), lens thickness (LT), central corneal...
Purpose: The objective of this study is to evaluate the in vivo corneal biomechanical response three laser refractive surgeries. Methods: Two hundred and twenty-seven patients who submitted transepithelial photorefractive keratectomy (tPRK), femtosecond laser-assisted in-situ keratomileusis (FS-LASIK), or small-incision lenticule extraction (SMILE) were included study. All cases examined with Corvis ST preoperatively (up 3 months) postoperatively at 1, 3, 6 months, differences main device...
Purpose To evaluate axial length (AL) measurement failure rate with the IOLMaster (Carl Zeiss AG, Germany) and Lenstar LS 900 (Haag-Streit Switzerland) in eyes cataract. Methods Two hundred ninety-six of 170 patients cataract were enrolled. Cataract type severity graded using Lens Opacities Classification System III (LOCS III) AL measurements attempted (version 5.4) 1.1). Chi-squared analysis was used to assess if difference acquisition statistically significant between two devices. The...
The eye globe exhibits significant regional variation of mechanical behaviour. aim this present study is to develop a new experimental technique for testing intact globes in form that representative vivo conditions, and therefore suitable determining the material properties complete outer ocular tunic. A test rig has been developed provide closed-loop control either applied intra-ocular pressure or resulting apical displacement; measurement displacements across external surface using...
To evaluate whether different corneal cross-linking (CXL) irradiances, all with the same delivered total energy, achieve similar increases in material stiffness.One hundred twenty-six healthy white Japanese rabbits were randomly divided into seven groups (n = 18 each). After removing epithelium of left corneas, six exposed to riboflavin (0.22% concentration by volume) and ultraviolet-A (370 nm) at CXL irradiations, dose (5.4 J/cm2), ranging from 3 mW/cm2 for 30 minutes 90 1 minute. The...
Purpose: To investigate the characteristics of optic nerve head (ONH) in myopia using swept-source optical coherence tomography (SS-OCT). Methods: Participants were divided into three groups according to axial length (AL). The disc morphology, retinal fiber layer (RNFL) thickness, and radial peripapillary capillary (RPC) vessel density (VD), tilt, rotation, Bruch's membrane opening distance (BMOD), border (BL), tissue angle, focal lamina cribrosa (LC) defects, β- γ-zone atrophy (PPA),...
To assess the diurnal changes in corneal biomechanics healthy young adults. At Wenzhou Medical University Eye Hospital China, a prospective case series. Each subject had six Corvis ST examinations, from 10:00 on first day to 6:00 following day, at 4-hour intervals. The data collected included biomechanically corrected IOP (bIOP), central thickness (CCT) and dynamic response (DCR) parameters, namely deformation amplitude (DA), ratio between DA values apex 2 mm (DAR2), integrated inverse...
Purpose To evaluate the effect of posterior scleral reinforcement in controlling high myopic axial progression young patients. Methods Only one eye each patient had surgery. Before surgery and at postoperative follow-up, best corrected visual acuity, intraocular pressure, refractive errors, indirect ophthalmoscopy, B-type ultrasonography, IOLMASTER reflected light biometry were performed on both eyes. The changes length errors from baseline compared between eyes contralateral Results Thirty...
Purpose To assess the repeatability and agreement of anterior segment measurements between an optical biometer (IOLMaster 700) using swept-source coherence tomography a Scheimpflug–Placido tomographer (Sirius) in patients scheduled for corneal refractive surgery. Setting Eye Hospital Wenzhou Medical University, Zhejiang, China. Design Prospective case series. Methods The parameters, including central thickness (CCT), chamber depth (ACD), aqueous depth, keratometry (K) values, astigmatism, J0...
This study aimed to investigate the eye movement characteristics and visual fatigue of virtual reality games with different interaction modes. Eye data were recorded using built-in tracker VR device parameters calculated from raw data. The Visual Fatigue Scales Simulator Sickness Questionnaire used subjectively assess overall discomfort experience. Sixteen male 17 female students recruited for this study. Results showed that both primary 360 mode could cause after 30 min gameplay,...
Purpose: The aim of this study was to evaluate the repeatability central corneal thickness (CCT) measurements in normal eyes using 2 new noncontact specular microscopes (NCSMs) EM-3000 (Tomey, Japan) and SP-02 (CSO, Italy) compare results with those obtained from an SP-3000P NCSM (Topcon, ultrasound pachymetry (USP). Methods: Seventy subjects were enrolled a prospective study. A single experienced ophthalmologist performed tests each 4 instruments. Measurements right eye during same session....
Optical coherence tomography (OCT) is a non-invasive imaging system that can be used to obtain images of the anterior segment. Automatic segmentation these will enable them construct patient specific biomechanical models human eye. These could help with treatment planning and diagnosis patients.A novel graph cut technique using regional shape terms was developed. It evaluated by segmenting 39 OCT The results this were compared manual previously reported level set technique. Three different...
The study of corneal biomechanics in vivo has been evolving fast recent years. While an organised structure is necessary for its transparency, resistance to occasional external insults and bearing the intraocular pressure (IOP), which several clinically relevant events can disturb. This review focuses on three techniques that are available clinical use, namely Ocular Response Analyzer (Reichert Ophthalmic Instruments, Buffalo, NY, USA), Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany)...
This study seeks to evaluate the ability of updated stress strain index (SSIv2) and other Corvis ST biomechanical parameters in distinguishing between keratoconus at different disease stages normal eyes.
To analyze the correlation between orbital compliance and retinal vessel density (VD) based on dynamic Scheimpflug analyzer (Corvis ST) optical coherence tomographic angiography (OCT-A).
Optical coherence tomography (OCT) images can provide quantitative measurements of the eye's entire anterior segment. A new technique founded on a newly proposed level set-based shape prior segmentation model has been developed for automatic cornea's and posterior boundaries. This comprises three major steps: removal regions containing irrelevant structures artifacts, estimation location using thresholding technique, application to improve segmentation. The performance our is compared...