A5038692859- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Obesity, Physical Activity, Diet
- Mobile Health and mHealth Applications
- Antibiotics Pharmacokinetics and Efficacy
- Interprofessional Education and Collaboration
- Health Systems, Economic Evaluations, Quality of Life
- Health Policy Implementation Science
- Clostridium difficile and Clostridium perfringens research
- Geriatric Care and Nursing Homes
- Nosocomial Infections in ICU
- Innovative Human-Technology Interaction
- Pneumonia and Respiratory Infections
- Immunodeficiency and Autoimmune Disorders
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Mental Health and Patient Involvement
- Air Traffic Management and Optimization
- Ultrasound in Clinical Applications
- European Political History Analysis
- Immune responses and vaccinations
- Digital Mental Health Interventions
- Healthcare cost, quality, practices
Walter Reed Army Institute of Research
2024
American Society for Microbiology
2019-2024
Lexington VA Health Care System
2015-2022
University of Kentucky
1998-2020
The University of Texas at Austin
2019-2020
United States Department of Veterans Affairs
2018
Veterans Health Administration
2018
VA Salt Lake City Healthcare System
2015
John Wiley & Sons (United Kingdom)
2014
The Ohio State University
1977-2012
The emergence of multidrug-resistance (MDR), production extended-spectrum β-lactamases, and carbapenemase in members fermentative gram-negative bacilli are a serious threat to public health.The aim this study was determine the burden multi-drug resistance, β-lactamases (ESBLs), Gram-negative Ethiopian Public Health Institute.A cross-sectional carried out from December 2017 June 2018. Different clinical samples were collected, inoculated, incubated according standard protocols related each...
Leishmaniasis is a neglected tropical disease that estimated to afflict over 12 million people. Current drugs for leishmaniasis suffer from serious deficiencies, including toxicity, high cost, modest efficacy, primarily parenteral delivery, and emergence of widespread resistance. We have discovered developed natural product-inspired tambjamine chemotype, known be effective against Plasmodium spp, as novel class antileishmanial agents. Herein, we report in vitro vivo activities, detailed...
The specific aim for this pilot study was to evaluate the effectiveness of a nutrition and media literacy intervention targeting elementary students their parents. purpose increase child fruit vegetables (FV) consumption change home environment (measured with FV availability accessibility parental social support). During intervention, learned about nutrition, role plays in shaping values concerning developed campaign A quasi-experimental research design used intervention. effective changing...
Purpose: To examine the effects of a relationship‐enhancing program care (REPC) on resident and provider outcomes. Design Methods: A quasi‐experimental, repeated measures design, with intervention comparison groups. Questionnaires were distributed to 50 residents, observations conducted 40 residents 34 nursing staff at baseline 3 months after intervention, two Canadian home units. An investigator‐designed educational based Winnicott's theory relationships empirical literature, was provided...
Previous estimates of the excess costs due to health care-associated infection (HAI) have scarcely addressed issue time-dependent bias.We examined bias by estimating care attributable an HAI methicillin-resistant Staphylococcus aureus (MRSA) using a unique dataset in Department Veterans Affairs (VA) that makes it possible distinguish between occurred before and after HAI. In addition, we compare our results those from 2 other estimation strategies.Using historical cohort study design...
Multidrug resistant, extremely drug-resistant, pan-drug carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings posing a growing threat to public health.The study was aimed detect phenotypically characterize carbapenem no- susceptible bacilli at the Ethiopian Public Health Institute.A prospective cross-sectional conducted from June 30, 2019, May 2020, national reference laboratory of Institute. Clinical samples were collected,...
Abstract Background Carbapenem-resistant Enterobacteriaceae (CRE) cause approximately 13 100 infections, with an 8% mortality rate in the United States annually. Carbapenemase-producing CRE (CP-CRE) a subset of infections have much higher rates (40%–50%). There has been little research on characteristics unique to CP-CRE. The goal current study was assess differences between US veterans non-CP-CRE and those CP-CRE cultures. Methods A retrospective cohort cultures from 2013–2018 their...
The article focuses on a report which examines contemporary slavery in Great Britain. It cites that the offers sobering account of human exploitation notes study determines most significant forms and trafficking, such as bonded labour, serfdom child labour. According to UNICEF, there are at any one time nearly 5,000 sex workers Keywords: Human trafficking Language: en
The importance of regular physical activity is well documented, yet according to epidemiological surveillance data, inactivity among all age groups persists. Past attempts promote focused on individual-level changes; current approaches focus environmental changes that will provide opportunities for whole communities be active. ecological has led an increase in funding and research regarding supports activity. As this a new area research, much work needs done improve the ability assess...
Seventeen methicillin-resistant Staphylococcus aureus (MRSA) with unique genotypes were examined to determine if resistance occurs more frequently ciprofloxacin or levofloxacin. The mean single-step rate 4 x MIC of was 1.05 10(-5) (range <4.82 10[-11] 5.06 10[-5]), and that levofloxacin 4.03 10(-6) <3.57 10[-13] 4.10 10[-5]) (P < 0.05). When serially passaged, the MICs increased 3.0 +/- 1.5-fold 1.8 1.4-fold, respectively Only four strains became resistant levofloxacin, but eight...
Abstract Laboratory identification of carbapenem-resistant Enterobacteriaceae (CRE) is a key step in controlling its spread. Our survey showed that most Veterans Affairs laboratories follow VA guidelines for initial CRE identification, whereas 55.0% use PCR to confirm carbapenemase production. Most respondents were knowledgeable about guidelines. Barriers included staffing, training, and financial resources.
Rural residents face numerous challenges in accessing quality health care for management of chronic diseases (eg, obesity, diabetes), including scarcity services and insufficient public transport. Digital interventions, which include modalities such as internet, smartphones, monitoring sensors, may help increase rural residents’ access to care. While digital interventions have become an increasingly popular intervention strategy address research examining the use technological tools obesity...
In this report, a simulation system called the Collaborative Airport Traffic System (CATS) was used as testbed to study human factors issues that arise in design of departure metering program [1-11] manage inventory delivered spots at an airport over time. The focus particular on procedures, functional requirements, information requirements and interface concepts for supporting collaboration [12-19] between ARTCC TRACON TMCs Departure Reservoir Coordinator (DRC) responsible managing during...
Carbapenem-resistant Enterobacterales bloodstream infections (CRE-BSI) increase mortality three-fold compared with carbapenem-susceptible infections. Because these are rare, there is a paucity of information on associated different treatment regimens. This study examines regimens and association in-hospital, 30 day 1 year risk for patients CRE-BSI.This retrospective cohort identified hospitalized within the Veteran Affairs (VA) from 2013 to 2018 positive CRE blood culture started antibiotic...
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) and Pseudomonas aeruginosa (CRPA) are drug-resistant pathogens causing high mortality rates with limited treatment options. Understanding the incidence of these organisms laboratory knowledge testing protocols is important for controlling their spread in healthcare settings. This project assessed how often Veterans Affairs (VA) facilities identify CRAB CRPA practices used. Method: An electronic survey was distributed to 126 VA...
Background: Aeromonas hydrophila is one species of the genus that received increasing attention as an opportunistic pathogen because its association with human diseases associated a wide range illnesses in humans, including gastroenteritis, wound infections, septicemia, meningitis, peritonitis, endocarditis, osteomyelitis both immunocompromised and healthy host.Case: This was 1-month-an old female child history fever, not sucking breast, exhibiting\symptoms meningitis born from 23 years...
Well-tolerated and novel antimalarials that can combat multiple stages of the parasite life cycle are desirable but challenging to discover develop. Herein, we report results for natural product-inspired tambjamine antimalarials. We show they potent against liver, asexual erythrocytic, sexual erythrocytic stages. Notably, our lead candidate
CDM Industry Lead: "We should be managing the queues to get right airplanes out there at time increase throughput and efficiency."