Tadesse Lejisa

ORCID: 0000-0003-0382-5000
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Bacterial Identification and Susceptibility Testing
  • Clinical Laboratory Practices and Quality Control
  • Chronic Kidney Disease and Diabetes
  • Global Public Health Policies and Epidemiology
  • SARS-CoV-2 detection and testing
  • Antibiotic Use and Resistance
  • COVID-19 diagnosis using AI
  • SARS-CoV-2 and COVID-19 Research
  • Tuberculosis Research and Epidemiology
  • Bone and Joint Diseases
  • Venous Thromboembolism Diagnosis and Management
  • Artificial Intelligence in Healthcare
  • Meta-analysis and systematic reviews
  • Blood Coagulation and Thrombosis Mechanisms
  • Cardiovascular Health and Risk Factors
  • Cardiovascular Health and Disease Prevention
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Public Health and Nutrition
  • Atrial Fibrillation Management and Outcomes
  • Diagnosis and treatment of tuberculosis
  • Potassium and Related Disorders
  • Blood groups and transfusion
  • Vibrio bacteria research studies
  • Reproductive tract infections research

Ethiopian Public Health Institute
2019-2025

St. Paul's Hospital Millennium Medical College
2024

Addis Ababa University
2021

Objectives Although the burden of syphilis is slightly increasing worldwide, there are a limited number rapid, simple-to-use, accurate and cost-effective diagnostic tools available. Thus, we aimed to determine performance Treponema pallidum particle agglutination (TPPA) test (hereafter called index test) against an electrochemiluminescence immunoassay (ECLIA) reference test). We selected available treponemal evaluate which not currently in use Ethiopia. Methods conducted multicentre...

10.1136/sextrans-2024-056298 article EN cc-by-nc Sexually Transmitted Infections 2025-01-22

Multidrug resistant, extremely drug-resistant, pan-drug carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings posing a growing threat to public health.The study was aimed detect phenotypically characterize carbapenem no- susceptible bacilli at the Ethiopian Public Health Institute.A prospective cross-sectional conducted from June 30, 2019, May 2020, national reference laboratory of Institute. Clinical samples were collected,...

10.1371/journal.pone.0256556 article EN cc-by PLoS ONE 2021-12-02

Chronic kidney disease (CKD), which is characterized by its asymptomatic nature until an end stage, one of the most common public health problems in world. Thus, a regular checkup, especially for those individuals with high risk groups inevitably important, and screening has been done laboratory findings. However, developing countries, including Ethiopia CKD are rarely done, it becoming to hear sudden death from failure. Therefore, we aimed screen serum electrolyte levels estimated...

10.1186/s12882-020-02166-0 article EN cc-by BMC Nephrology 2020-11-18

Iron-deficiency anemia (IDA) is a common type of nutritional in low-income countries, including Ethiopia. However, there limited data on iron deficiency prevalence and associated factors Ethiopia, particularly for children aged 2 to 5 years.To establish the risk factors, focusing iron-rich food consumption among years southern Ethiopia.A community-based cross-sectional study was conducted Ethiopia 2017, involving 331 randomly selected old. A structured questionnaire used collect information...

10.7717/peerj.11649 article EN cc-by PeerJ 2021-06-28

Natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or vaccination triggers antibody production against key viral antigens. However, there is limited evidence on the levels of antibodies produced in naturally infected individuals compared to those vaccinated Ethiopia. Therefore, we aimed detect and compare SARS-CoV-2 by individuals.

10.1186/s12985-024-02443-6 article EN cc-by-nc-nd Virology Journal 2024-08-19

The proportion of patients with end-stage renal disease caused by diabetes has progressively increased during the last few decades. Serum creatinine level is most commonly used biochemical parameter to estimate GFR in routine practice. However, 50% can be lost before significant elevation serum creatinine. Cystatin C found a new promising marker for early detection diseases.The aim this study was determine value cystatin and levels type 2 mellitus.A hospital-based comparative cross-sectional...

10.2147/dmso.s279949 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2020-12-01

Non-communicable diseases (NCDs) are increasingly becoming the global cause of premature death encompassing cardiovascular (CVDs), cancer, respiratory and diabetes mellitus. However, cardiometabolic risk factors in general population, especially among high-risk groups have rarely been assessed Ethiopia. The study aimed to assess prevalence metabolic syndrome, its components associated staff Ethiopian Public Health Institute (EPHI). An institutional-based cross-section was conducted from...

10.1038/s41598-021-99913-6 article EN cc-by Scientific Reports 2021-10-19

Abstract Background : Non-communicable diseases (NCDs) are increasingly becoming the global cause of premature death encompassing cardiovascular (CVDs), cancer, respiratory and diabetes mellitus. However, early identification cardiometabolic risk factors in general population, especially among high-risk groups has rarely been assessed Ethiopia. Purpose The study aimed to assess magnitude associated Ethiopian Public Health Institute (EPHI) staff members. Methodology An institutional-based...

10.21203/rs.3.rs-132408/v1 preprint EN cc-by Research Square (Research Square) 2020-12-23

Abstract Background Multi-drug resistant, extremely drug-resistant, pan-drug carbapenem-resistant, and carbapenemase-producing gram-negative bacteria are becoming more common in health care settings posing a growing threat to public health. Objective The study was aimed detect phenotypically characterize carbapenem non susceptible bacilli at Ethiopian Public Health Institute. Materials methods Prospective cross-sectional conducted from June 30, 2019, May 2020, the national reference...

10.1101/2021.08.17.456671 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-08-17

Background: Even though several factors affect reference intervals (RIs), company-derived values are currently in use many laboratories worldwide. However, few or no data available regarding serum proteins RIs, especially resource-limited countries such as Ethiopia. Objective: To establish RIs for protein electrophoresis of apparently healthy adults Addis Ababa, Methods: A cross-sectional study was conducted on a total 297 from April to October 2019 four selected sub-cities (Akaki, Kirkos,...

10.2147/ijgm.s376450 article EN cc-by-nc International Journal of General Medicine 2022-08-01

It has been reported that inappropriate acute thrombus formation is the pathophysiological substrate underlying increased risk and severity of target organ damage in hypertension. However, relationship between hypertension D-dimer not well characterized. This study was aimed to assess plasma level its correlation with disease among hypertensive at Yikatit 12 Hospital Medical College (Y12HMC), Ethiopia. A comparative cross-sectional conducted Y12HMC 100 participants (60 40 controls). The...

10.20372/jsid/2020-31 article EN 2020-06-15

Background: Early detection of extended-spectrum β-lactamases (ESBLs) producing bacteria is critical for infection prevention and control. Numerous phenotypic approaches automated systems have been developed detecting ESBL bacteria. However, there a scarcity data in Ethiopia regarding the most reliable, simple, cost-effective methods ESBL-producing This study, therefore, aimed to evaluate diagnostic performance three Methods: In this 117 isolates Klebsiella pneumoniae, Escherichia coli,...

10.34172/ajcmi.2022.01 article EN Avicenna Journal of Clinical Microbiology and Infection 2022-03-29

Comparison of assay results is very important for having a comparable backup analyzer to provide quality laboratory service without interruption. Even though, several factors affect by different instruments, little or no data available regarding comparison between Cobas 6000 (c501) and integra 400 plus in the study area. Thus, present was aimed compare two fully auto-mated clinical chemistry analyzers: Integra Plus at National Clinical Chemistry Reference Laboratory Ethiopian Public Health...

10.7754/clin.lab.2021.210734 article EN Clinical Laboratory 2022-01-01

Abstract Gynecological cancer patients experience malnutrition and Inflammation that play a pivotal role in the progression of cervical cancer. The aim present study was to assess inflammatory status through measurement biochemical markers. Hospital based comparative cross-sectional conducted on 50 healthy individuals. Blood collected analyzed gather hematological data. Demographic anthropometric data were also statistically analyzed.The mean age participants 52.4 years. Patients had...

10.21203/rs.3.rs-1756278/v1 preprint EN cc-by Research Square (Research Square) 2022-07-06
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