- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- COVID-19 Clinical Research Studies
- Cardiovascular Disease and Adiposity
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Effects of Exercise
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Pituitary Gland Disorders and Treatments
- Diabetes Treatment and Management
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Microbial Metabolism and Applications
- Viral Infections and Immunology Research
- Atherosclerosis and Cardiovascular Diseases
- Takotsubo Cardiomyopathy and Associated Phenomena
- Brain Tumor Detection and Classification
- Venous Thromboembolism Diagnosis and Management
- Social Media in Health Education
Magna Graecia University
2024-2025
University of Brescia
2020-2024
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2021-2024
Brescia University
2020-2024
Surgical Specialties (Canada)
2022-2023
Leiden University Medical Center
2020
Abstract Background Atrial fibrillation (AF) is a common heart rhythm disorder that associated with an increased risk of stroke and failure (HF). Initially, association between AF ion channel dysfunction was identified, classifying the pathology as predominantly electrical disease. More recently it has been recognized fibrosis structural atrial remodeling play driving role in development this arrhythmia also these cases. Purpose Understanding genetic determined could be important to better...
Heart failure (HF) is increasingly recognized as a heterogeneous cardiometabolic disorder, often in the context of overweight/obesity independently from diabetes. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce HF hospitalizations and cardiovascular mortality across ejection fraction (EF) categories, yet their early hemodynamic effects HF, with preserved (HFpEF) particular, remain underexplored. A prospective, single-center study included 20 consecutive patients receiving SGLT2i...
Aortic stenosis is the most prevalent valvular heart disease requiring intervention, especially in elderly population. Surgical aortic valve replacement and transcatheter implantation (TAVI) are well established treatment options for symptomatic patients with severe stenosis, as they provide a significant survival benefit. may have an important impact on patients’ quality of life (QoL). However, advanced age, comorbidities frailty limit beneficial effect interventions terms QoL. Current...
Estimation of left ventricular (LV) filling pressures in patients with a history atrial fibrillation (AF) is challenging due to lack reliable parameters. This study investigates the association between cardiac structure and function invasive mean pressure (LAP).
Transvenous lead extraction (TLE) has shown a safe and efficacy profile in the intraoperative short-term setting; however, data on long-term outcomes are limited.The purpose of this study was to assess prognostic factors patients who underwent TLE.Consecutive with cardiac implantable electronic device (CIED) TLE between 2014 2016 were retrospectively studied. The primary outcome composite endpoint death repeated stratified by infective/non-infective indication. Individual components also...
This study aimed to investigate the characteristics and outcomes of patients diagnosed with Brugada syndrome (BrS) who underwent implantable loop recorder (ILR) insertion during routine clinical activity. We conducted a comprehensive screening all consecutive BrS at our institution. analyzed baseline characteristics, arrhythmic findings, outcomes. Out 147 patients, 42 (29 %) received an ILR, 13 (9 cardioverter-defibrillator (ICD) placement, 92 (63 continued regular cardiological follow-up....
It has been widely reported that the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) attaches human cells by using Angiotensin Converting Enzyme (ACE2) receptor, but vascular impairment described during coronavirus disease 2019 (COVID-19) infection is primarily due to direct involvement of endothelial virus or secondarily inflammatory host response currently unknown. We therefore aimed demonstrate in vivo presence dysfunction six COVID-19 patients without cardiovascular risk...
Abstract Originally designed as anti-hyperglycemic drugs, Glucagon-Like Peptide-1 receptor agonists (GLP-1Ra) and Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have demonstrated protective cardiovascular effects, with significant impact on morbidity mortality. Despite several mechanisms been proposed, the exact pathophysiology behind these effects is not yet fully understood. Cardiovascular imaging key for evaluation of diabetic patients, an established role from identification early...
Objective Given that volumes of patients and interventions are important criteria to qualify as a reference centre (RC) for the European Reference Network on Rare Endocrine Conditions (Endo-ERN), present study aimed evaluate data were reported in original application against subsequent assessments activity review may define RCs using two main thematic groups (MTGs): Pituitary Thyroid, examples. Methods Review content forms continuous monitoring survey distributed RCs. A list ‘key procedures’...
Abstract Introduction The prevalence and impact of pulmonary embolism (PE) in patients with lead‐related infective endocarditis undergoing transvenous lead extraction (TLE) are unknown. Methods Twenty‐five consecutive vegetations ≥10 mm at transoesophageal echocardiography were prospectively studied. Contrast‐enhanced chest computed tomography (CT) was performed before (pre‐TLE) after (post‐TLE) the procedure. Results Pre‐TLE CT identified 18 (72%) subclinical PE. size PE did not differ...
The multiple beneficial effects of sacubitril/valsartan in the treatment heart failure with reduced ejection fraction are vastly known, but still no or few mentions have been made regarding its on endothelial dysfunction and arterial stiffness.To understand more deeply if may a role function stiffness, 15 patients dilated cardiomyopathy left ventricular (LVEF) were evaluated through transthoracic echocardiography, peripheral tonometry (EndoPAT®) applanation (SphygmoCor® Px system). These...