A5081522268- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Advanced MRI Techniques and Applications
- Cardiac Arrhythmias and Treatments
- Transplantation: Methods and Outcomes
- Cardiomyopathy and Myosin Studies
- Coronary Artery Anomalies
- Viral Infections and Immunology Research
- Mechanical Circulatory Support Devices
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- Cardiac pacing and defibrillation studies
- Coronary Interventions and Diagnostics
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Effects of Exercise
- Pericarditis and Cardiac Tamponade
- Atrial Fibrillation Management and Outcomes
- Takotsubo Cardiomyopathy and Associated Phenomena
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
Magna Graecia University
2020-2025
Harefield Hospital
2022-2025
Guy's and St Thomas' NHS Foundation Trust
2022-2025
University of Palermo
2025
Royal Brompton & Harefield NHS Foundation Trust
2022-2024
Royal Victoria Hospital
2023
University of Ulster
2023
Royal Brompton Hospital
2022-2023
King's College London
2022
National Research Council
2020
Accurate risk stratification for patients with non-dilated left ventricular cardiomyopathy (NDLVC) remains challenging due to lack of dedicated clinical trials. This post-hoc analysis aims delineate the arrhythmic and assess incremental value cardiac magnetic resonance (CMR) imaging in DERIVATE (CarDiac MagnEtic Resonance Primary Prevention Implantable CardioVerter DebrillAtor ThErapy) study cohort meeting NDLVC diagnostic criteria. Patients from registry were identified absence (LV)...
The complete transposition of the great arteries (C-TGA) is a congenital cardiac anomaly characterized by reversal main arteries. Early detection and precise management are crucial for optimal outcomes. This review emphasizes integral role multimodal imaging, including fetal echocardiography, transthoracic echocardiography (TTE), cardiovascular magnetic resonance (CMR), computed tomography (CCT) in diagnosis, treatment planning, long-term follow-up C-TGA. Fetal plays pivotal prenatal...
Up to 15% of coronavirus disease 2019 (COVID-19) patients experience severe clinical presentation, resulting in acute respiratory distress (ARDS) and finally death. N-terminal natriuretic peptide (NT-proBNP) is associated with a worse prognosis ARDS. However, whether or not this can help discriminate high-risk COVID-19 remains unclear. Therefore, meta-analysis, we summarized the available evidence on NT-proBNP admitted for COVID-19. Pooled mean, mean differences (MD) standardized difference...
Changes in cardiac mechanics after correction of severe Aortic Stenosis (AS) are under-investigated. Myocardial Work (MW) is emerging as a useful non-invasive correlate invasively measured myocardial performance and oxygen consumption. The aim this study was to assess the usefulness MW clinical management patients with AS undergoing transcatheter aortic valve implantation (TAVI). Consecutive referred for TAVI were included observational study. Echocardiograms performed before measure Global...
Despite many advances in surgical repair during the past few decades, majority of tetralogy Fallot patients continue to experience residual hemodynamic and electrophysiological abnormalities. The actual issue, which has yet be solved, is understanding how this disease evolves each individual patient and, as a result, who truly at risk sudden death, well proper timing pulmonary valve replacement (PVR). Our responsibility should select most appropriate time for patient, going above beyond...
Early diagnosis of idiopathic pulmonary fibrosis (IPF) is fundamental to slow disease progression; multidisciplinary teams (MDTs) play a central role in posing the final IPF, thus aiming improve patient outcomes. However, practical implementation MDTs clinical real-life settings may be hindered by lack local expertise or time constraints, with being made without support complementary professional health care figures. This study aims evaluate impact MDT meetings on latency between symptom...
Heart failure (HF) is increasingly recognized as a heterogeneous cardiometabolic disorder, often in the context of overweight/obesity independently from diabetes. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) reduce HF hospitalizations and cardiovascular mortality across ejection fraction (EF) categories, yet their early hemodynamic effects HF, with preserved (HFpEF) particular, remain underexplored. A prospective, single-center study included 20 consecutive patients receiving SGLT2i...
Aims To investigate the changes in left atrial strain (LAS) after correction of severe aortic stenosis (AS) with transcatheter valve replacement (TAVR) and assess its prognostic impact. Methods results One hundred consecutive patients symptomatic AS who underwent TAVR at Magna Graecia University Catanzaro echocardiographic examination including assessment LAS before TAVR. Independent investigators collected outcome data information. The primary study was difference ΔLAS (postTAVR–preTAVR)...
Cardiovascular calcification is a multifactorial and complex process involving an array of molecular mechanisms eventually leading to calcium deposition within the arterial walls. This increases stiffness, decreases elasticity, influences shear stress events related increased risk morbidity mortality associated with cardiovascular disease. In numerous in vivo vitro models, warfarin therapy has been shown cause vascular wall. However, exact formation remain largely unknown, although several...
Background: Non-invasive prediction of critical coronary artery stenosis (CAST) in patients with disease (CAD) is challenging. Strain parameters can often capture an impairment regional longitudinal function; however, they are load dependent. A novel non-invasive method to estimate Myocardial Work (MW) has been recently proposed, showing a strong correlation invasive work measurements. Our aim was investigate the ability MW predict ischaemic risk area underlying CAST. Methods and Results:...
Abstract Aims In ∼5–15% of all cases acute coronary syndromes (ACS) have unobstructed coronaries on angiography. Cardiac magnetic resonance (CMR) has proven useful to identify in most patients the underlying diagnosis associated with this presentation. However, role CMR reclassify from initial suspected condition not been clarified. The aim study was assess proportion MINOCA, or non-MINOCA, that reclassifies an alternative original clinical suspicion. Methods and results A retrospective...
Assessment of intracardiac flow dynamics has recently acquired significance due to the development new measurement methods based on echocardiography. Recent studies have demonstrated that cardiac abnormalities are associated with changes in vortical flows. Yet, no previous study assessed impact aortic stenosis (AS) vortices. This aims explore clinical potential additional information provided by quantifying patients AS.