Philipp P. Caffier

ORCID: 0000-0001-8492-9586
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About
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Research Areas
  • Voice and Speech Disorders
  • Dysphagia Assessment and Management
  • Ear Surgery and Otitis Media
  • Tracheal and airway disorders
  • Respiratory and Cough-Related Research
  • Allergic Rhinitis and Sensitization
  • Nasal Surgery and Airway Studies
  • Head and Neck Cancer Studies
  • Phonetics and Phonology Research
  • Musicians’ Health and Performance
  • Music and Audio Processing
  • Ocular Surface and Contact Lens
  • Airway Management and Intubation Techniques
  • Ear and Head Tumors
  • Sinusitis and nasal conditions
  • Mast cells and histamine
  • Speech Recognition and Synthesis
  • Salivary Gland Tumors Diagnosis and Treatment
  • Olfactory and Sensory Function Studies
  • Hearing, Cochlea, Tinnitus, Genetics
  • Head and Neck Surgical Oncology
  • Language Development and Disorders
  • Laser Applications in Dentistry and Medicine
  • Cytomegalovirus and herpesvirus research
  • Trauma Management and Diagnosis

Humboldt-Universität zu Berlin
2006-2024

Freie Universität Berlin
2021-2024

Charité - Universitätsmedizin Berlin
2013-2024

Humboldt State University
2005-2006

Federal Institute for Occupational Safety and Health
2003

Berlin Heart (Germany)
1942

Universitäts Frauenklinik
1930

Increasing tinnitus compliance and coping are desirable aims of successful treatment in chronic tinnitus. However, application established procedures such as retraining therapy (TRT) is often relatively short. In addition, the value control instruments (TCI) questionable, especially for minor severity levels tinnitus, comparability results low. To evaluate long-term changes tinnitus-related distress, defined psychometric data were collected patients with compensated (cT) or decompensated...

10.1097/01.aud.0000240504.77861.1a article EN Ear and Hearing 2006-11-02

Objectives/Hypothesis To prove the diagnostic value of autofluorescence endoscopy (AFE) and white light laryngostroboscopy (WLS) versus gold standard microlaryngoscopy with histopathological examination in differential diagnostics laryngeal lesions for experienced phoniatricians laryngologists, using PENTAX SAFE‐3000 system. Study Design Exploratory cohort study. Methods High‐resolution rigid WLS was executed 32 consecutive patients initial manifestation benign, precancerous, malignant vocal...

10.1002/lary.23931 article EN The Laryngoscope 2013-04-22

The international nine-item Voice Handicap Index (VHI-9i) is a clinically established short-scale version of the original VHI, quantifying patients’ self-assessed vocal handicap. However, current impairment classification based on percentiles. main goals this study were to establish test–retest reliability and sound statistical basis for VHI-9i severity levels. Between 2009 2021, 17,660 consecutive cases documented. A total 416 pairs 3661 unique with complete multidimensional voice...

10.3390/jcm10153325 article EN Journal of Clinical Medicine 2021-07-28

Background The purpose of this study was to evaluate long-term outcomes an outpatient-based diode laser inferior turbinate reduction (ITR) in therapy-refractory rhinitis medicamentosa (RM). Methods In a prospective clinical investigation, 42 consecutive RM patients underwent videoendoscopic ITR with after topical anesthetic preparation. Intra- and perioperative details were recorded including the occurrence bleeding, crusting, pain, or discomfort. Treatment efficiency assessed by follow-ups...

10.2500/ajr.2008.22.3199 article EN American Journal of Rhinology 2008-07-01

To evaluate the efficacy of novel topical immune modulator tacrolimus in chronic uninfectious otherwise therapy-resistant external otitis (EO).Prospective clinical study.There were 53 patients aged 5 to 83 years. An ear wick containing 0.1% ointment (Protopic) was inserted into auditory canal every 2nd 3rd day. Altogether, changed three times. The pre-, intra- and posttherapeutic state parameters otalgia, edema, otorrhea, erythema, pruritus, desquamation rated by means a 6-point score...

10.1097/mlg.0b013e31804b1aad article EN The Laryngoscope 2007-04-17

Long-term Eustachian tube dysfunction (ETD) predisposes to various secondary middle ear diseases. Most surgical and prosthetical interventions on the itself have proven be ineffective, whereas surgeries treat sequelae of ETD without major influence underlying tubal pathology. The purpose our study was evaluate outcome laser tuboplasty (LETP) function associated otological symptoms in topically anesthetized patients with intact or perforated eardrums.In a prospective clinical investigation,...

10.1097/aud.0b013e3181e85614 article EN Ear and Hearing 2010-06-25

Vardenafil (Levitra(R)) represents a potent and highly selective phosphodiesterase type 5 (PDE5) inhibitor, which is established for treatment of various diseases. There are several unpublished reports from patients stating that vardenafil has considerable therapeutic effect on their concomitant tinnitus. This pilot study was conducted to specifically assess the in with chronic tinnitus.This trial based prospective, randomized, double-blind, placebo-controlled, parallel group design....

10.1186/1477-5751-8-3 article EN cc-by Journal of Negative Results in BioMedicine 2009-02-17

Abstract Objectives To compare continuous (C‐IONM) vs intermittent intraoperative neuromonitoring (I‐IONM) in complex benign thyroid surgery, and to follow up patients with loss of signal (LOS) or unilateral vocal fold paralysis (UVFP). Design Retrospective clinical study, prospective case series. Setting University hospital academic teaching Charité—University Medicine Berlin, Germany. Participants C‐IONM‐ I‐IONM‐assisted surgery was conducted 357 diagnosed recurrent goitre, Graves’...

10.1111/coa.13446 article EN Clinical Otolaryngology 2019-09-30

Voice range profile (VRP) and evaluation using the dysphonia severity index (DSI) represent essentials of instrument-based objective voice diagnostics are implemented in different standardized registration programs. The respective measurement results, however, show differences. aim study was to prove these differences statistically develop a new parameter, Vocal Extent Measure (VEM), which is not influenced by program. VRPs 97 subjects were recorded two examiners established programs DiVAS...

10.1155/2018/3836714 article EN cc-by BioMed Research International 2018-01-01

Functional and organic impairments of the singing voice are common career-threatening problems singers presenting in phoniatric laryngological departments. The objective was to evaluate efficacy phonosurgery, logopedic treatment vocal pedagogy functional singers, including investigation recently introduced parameter extent measure (VEM). In a prospective clinical study, analysis outcome 76 [57 female, 19 male; 38 ± 11 years (mean SD)] based on pre- post-therapeutic function diagnostics...

10.1007/s12325-018-0725-x article EN cc-by-nc Advances in Therapy 2018-06-15

There are few data analysing to what specific extent phonomicrosurgery improves vocal function in patients suffering from Reinke's oedema (RE). The recently introduced parameter measure (VEM) seems be suitable objectively quantify performance. pur- pose of this clinical prospective study was investigate the outcomes 60 RE (6 male, 54 female; 56 ± 8 years ([mean SD]) by its effect on subjective and objective parameters with particular regard VEM. Treatment efficacy evaluated at three months...

10.14639/0392-100x-1544 article EN cc-by-nc-nd Acta Otorhinolaryngologica Italica 2018-06-01

Habitual snoring without episodes of apnea or hypoventilation and respiratory related arousals is considered to be annoying any need for treatment. However, studies seem suggest an enormous psychosocial impact annoyance the bed partner. Apart from subjective questionnaires there still exists no generally accepted mode measurement that can describe objectively. We therefore adapted methods developed environmental medicine established a new snore score using psycho-acoustic parameters. For...

10.1088/0967-3334/28/1/003 article EN Physiological Measurement 2006-11-17

There are few data demonstrating the specific extent to which surgical intervention for vocal fold nodules (VFN) improves function in professional (PVU) and non-professional voice users (NVU). The objective of this study was compare quantify results after phonomicrosurgery VFN these patient groups. METHODS: In a prospective clinical study, surgery performed via microlaryngoscopy 37 female patients with chronic manifestations (38±12 yrs, mean±SD). Pre- postoperative evaluations treatment...

10.21091/mppa.2017.4035 article EN Medical Problems of Performing Artists 2017-12-01

Vibrato is one of the most frequently investigated parameters in singing. Most studies examine a very limited number sound samples to answer specific questions. In novel approach our interdisciplinary vibrato project, comprehensive database 1723 was compiled, containing examples from 30 operas, oratorio and 73 vocal exercises. Single tones undisturbed by orchestral were selected registers soprano, tenor, baritone bass according standardized classification system dividing voices into either...

10.1109/taslp.2021.3054299 article EN IEEE/ACM Transactions on Audio Speech and Language Processing 2021-01-01

Recurrent exacerbation in chronic recalcitrant external otitis (EO) often warrants multidisciplinary treatment and collaboration with a dermatologist. The aim of this pilot study was to ascertain the efficacy topical tacrolimus ointment application chronic, non-infectious therapy-resistant EO. In prospective clinical study, 0.1% examined 53 patients therapy-refractory EO confirmed etiology. Clinical examination took place prior (V1), at end (V2) during follow-up investigations (V3) 28 over...

10.1684/ejd.2007.0238 article EN PubMed 2007-08-04

Voice timbre is defined as sound color independent of pitch and volume, based on a broad frequency band between 2 4 kHz. Since there are no specific parameters, previous studies have come to the very general conclusion that center frequencies singer's formants somewhat higher in voice types than lower ones. For specification, database was created containing 1723 examples various types. The energy distribution bands extracted for quantitative analysis. When function reached 50%, corresponding...

10.1038/s41598-022-22821-w article EN cc-by Scientific Reports 2022-10-26

Objective To develop a three‐dimensional (3D) laryngostroboscopic examination unit, compare the optic playback quality in relation to established 2D procedures, and report first case series using 3D rigid laryngostroboscopy for diagnosis management of laryngotracheal diseases. Study Design Laboratory study, prospective series. Methods The optical efficacy newly developed endoscopes was examined laboratory setting. Diagnostic suitability investigated 100 subjects (50 male, 50 female)...

10.1002/lary.27260 article EN The Laryngoscope 2018-10-17

Objectives/Hypothesis To evaluate the efficacy of vocal fold (VF) augmentation with calcium hydroxylapatite (CaHA) microspheres in surgically pretreated larynx glottal insufficiency. Study Design Prospective clinical pilot study. Methods After several prior reconstructive attempts (following tumor resection, VF paralysis, sulcus vocalis, and scarring), CaHA was injected under general anaesthesia using a transoral microlaryngoscopic approach 10 patients residual insufficiency ≤1.5 mm. The...

10.1002/lary.26261 article EN The Laryngoscope 2016-08-31

Instrument-assisted measuring procedures expand the options within phoniatric diagnostics by quantifying condition of voice. The aim this study was to examine objective treatment-associated changes recently developed vocal extent measure (VEM) and established dysphonia severity index (DSI) in relation subjective tools, i.e., self-evaluation via voice handicap (VHI-12) external evaluation auditory-perceptual assessment hoarseness ( H ). findings for (3 raters’ group assessment), VHI-12, DSI,...

10.1155/2020/4208189 article EN cc-by BioMed Research International 2020-01-23
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