A5017177846- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Cardiac Imaging and Diagnostics
- Dental Implant Techniques and Outcomes
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Head and Neck Cancer Studies
- Dental Erosion and Treatment
- Prostate Cancer Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Prostate Cancer Treatment and Research
- Animal Nutrition and Physiology
- Acute Myocardial Infarction Research
- Hepatitis B Virus Studies
- Allergic Rhinitis and Sensitization
- Dental Radiography and Imaging
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Gut microbiota and health
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Immune Cell Function and Interaction
- Advanced Radiotherapy Techniques
- Bone Tissue Engineering Materials
Humboldt-Universität zu Berlin
2018-2024
Charité - Universitätsmedizin Berlin
2015-2024
Freie Universität Berlin
1991-2024
Zimmer Biomet (Germany)
2015-2024
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2019-2022
University of Copenhagen
2022
Semmelweis University
2022
Zimmer Biomet (Netherlands)
2008-2019
Kiel University
2013
Institut für Medizinische Biometrie, Informatik und Epidemiologie
2009-2011
In the diagnosis of obstructive coronary artery disease (CAD), computed tomography (CT) is an accurate, noninvasive alternative to invasive angiography (ICA). However, comparative effectiveness CT and ICA in management CAD reduce frequency major adverse cardiovascular events uncertain.We conducted a pragmatic, randomized trial comparing with as initial diagnostic imaging strategies for guiding treatment patients stable chest pain who had intermediate pretest probability were referred at one...
To investigate the effects of luting agent and thermocycling on bond strengths to root canal dentine.Extracted maxillary canines (n =144) were filled divided into six groups 24 teeth each. Fibre posts (FRC Postec) inserted using agents: Panavia F, Multilink, Variolink II, PermaFlo DC, RelyX Unicem Clearfil Core. Each was sliced discs (thickness 1 mm) representing coronal, middle apical part canal. Push-out tests performed h after post insertion = 12) as well (5000x; 5-55 degrees C, 30 s)...
A study was undertaken to examine the effects of a phytogenic feed additive (PFA) containing essential oils thyme and star anise as lead active components on growth performance apparent ileal nutrient digestibility in broiler chickens. In total, 528 one-day-old Cobb male broilers were randomly divided into 4 dietary treatment groups with 6 replicate pens per group (22 birds each). The treatments control starter grower basal diet without PFA or 150, 750, 1,500 mg/kg PFA. Body weight, weight...
This study correlated the morphological characteristics with bond strengths of various resin cements used for bonding fiber posts to root canal dentin. Fifty glass‐fiber (FRC Postec Plus) were luted into canals extracted human anterior teeth using five ( n = 10): Panavia F 2.0, PermaFlo DC, Variolink II, RelyX Unicem, and Clearfil Core. Before insertion post, adhesive systems labeled fluorescein cement was rhodamine isothiocyanate. The roots sectioned three slices (of 2 mm thickness), each...
Weaned piglets were fed diets containing 57 (low) or 2425 (high) mg kg(-1) analytical grade ZnO for a period of 5 weeks. Intestinal contents sampled in weekly intervals and analyzed bacterial cell numbers main metabolites. The most severe effects high dietary zinc observed 1 week after weaning the stomach small intestine. Pronounced reductions Enterobacteriaceae Escherichia group as well Lactobacillus spp. three five studied species. impact diminished enterobacteria with increasing age, but...
Colorectal cancer (CRC) is the second most common cause of all deaths in Europe and Western world with a lifetime risk approximately 5%. Despite several improvements treatment patients unresectable CRC prognosis poor there need developing new strategies for metastatic chemorefractory disease. The S100 calcium binding protein A4 (S100A4) predicts metastasis formation reduced patient survival. S100A4 was previously identified as transcriptional target Wnt/β-catenin signaling pathway. Food Drug...
The number of elderly and care-dependent people is increasing, leading to increased risks adverse skin conditions. Skin care, including prevention treatment vulnerable skin, an essential part daily nursing practice in long-term residential settings. For many years, the research focus has been on individual problems xerosis cutis, incontinence-associated dermatitis, tears, pressure ulcers, intertrigo, although may be affected by several at same time.Aim present study was describe prevalence...
Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role symptomatic patients is less clear. Purpose To assess the of CAC scoring MACE participants with stable chest pain initially referred invasive coronary angiography (ICA). Materials and Methods This prespecified subgroup analysis from Diagnostic Imaging Strategies Patients With Stable Chest Pain Intermediate Risk Artery Disease (DISCHARGE)...
We assessed the risk and determined predictors of early epileptic seizures (ES) in patients with acute cerebral venous sinus thrombosis (CVST). A prospective series 194 consecutive CVST admitted to neurological wards two German university hospitals was analysed for frequency ES in-hospital mortality. Demographic, clinical radiological characteristics during stage were retrospectively significant association univariate multivariate analyses. During stage, 19 (9.8%) died. Early symptomatic...
Objectives: Toll-like receptors (TLRs) play an important role in the innate immune response to pathogens. TLR7 recognizes RNA of various viruses including HIV. The objective this study was examine influence individual genetic variations on susceptibility and progression HIV disease. Method: We genotyped a population 734 HIV-positive adults 545 healthy controls for three single nucleotide polymorphisms. frequency assessed related disease progression. Furthermore, we analyzed peripheral blood...
Abstract Aim To investigate instrumentation time, working safety and the shaping ability of two rotary nickel–titanium (NiTi) systems (Alpha System ProTaper Universal) in comparison to stainless steel hand instruments. Methodology A total 45 mesial root canals extracted human mandibular molars were selected. On basis degree curvature matched teeth allocated randomly into three groups 15 each. In group 1 prepared size 30 using a standardized manual preparation technique; 2 3 NiTi instruments...
Background. Toll-like receptors (TLRs) play an important role in the innate immune response to pathogens. TLR8 has been found recognize RNA derived from various viruses, including human immunodeficiency virus (HIV). Presently, very little is known about influence of genetic variation on susceptibility and progression HIV disease. Methods results. We genotyped a population 782 HIV-positive adults 550 healthy control subjects for 3 nonsynonymous single-nucleotide polymorphisms. that presence...
Short-term case cancellation causes frustration for anesthesiologists, surgeons, and patients leads to suboptimal use of operating room (OR) resources. In many facilities, >10% all cases are cancelled on the day surgery, thereby causing major problems OR management anesthesia departments. The effect hospital type service rate is unclear.In 25 hospitals different types (university hospitals, large community mid- small-size hospitals) we studied elective surgical following subspecialties over...
Atopic dermatitis (AD) is a chronic inflammatory skin disease with multifactorial pathogenesis and increasing incidence in the Western world. A genetically determined defective function of pattern recognition receptors such as toll-like (TLRs) has been proposed candidate mechanism AD.To study impact genetic predisposition five genes encoding for recognition-related molecules phenotype AD.We examined nine different single-nucleotide polymorphism (SNP) frequencies TLR1, -2, -4, -9 adapter...
Summary Pharmacological levels of zinc oxide (ZnO) can improve the health weaning piglets and influence intestinal microbiota. This experiment aimed at studying dose–response effect five dietary concentrations ZnO on small bacteria metabolite profiles. Fifteen piglets, weaned 25 ± 1 days age, were allocated into groups according to body weight litter. Diets formulated contain 50 (basal diet), 150, 250, 1000 2500 mg zinc/kg by adding analytical‐grade (>98% purity) basal diet fed ad libitum...
Abstract Aim: To evaluate and compare the microbiological effects of hand instruments, Er:YAG‐laser, sonic, ultrasonic scalers in patients with chronic periodontitis. Patient perception each treatment was documented. Material Methods: From 72 patients, bacterial samples were collected from deepest pocket quadrant (total: 288 sites). A polymerase chain reaction kit estimated amount Aggregatibacter ( Actinobacillus ) actinomycetemcomitans Aa ), Porphyromonas gingivalis Pg Prevotella intermedia...