A5080140151- Cardiac Health and Mental Health
- Acute Ischemic Stroke Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Global Cancer Incidence and Screening
- Health and Medical Studies
- Obesity, Physical Activity, Diet
- Patient-Provider Communication in Healthcare
- Cardiovascular Function and Risk Factors
- Palliative Care and End-of-Life Issues
- Health Promotion and Cardiovascular Prevention
- Acute Myocardial Infarction Research
- Stroke Rehabilitation and Recovery
- Neuroendocrine Tumor Research Advances
- Clinical practice guidelines implementation
- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Research Studies
- Cancer survivorship and care
- Blood Pressure and Hypertension Studies
- Medical Practices and Rehabilitation
- Cardiovascular Effects of Exercise
- Neuroblastoma Research and Treatments
- Mental Health Treatment and Access
- Economic and Financial Impacts of Cancer
- Coronary Interventions and Diagnostics
Charité - Universitätsmedizin Berlin
2014-2025
Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit
2019-2025
University of Copenhagen
2022
Semmelweis University
2022
Humboldt-Universität zu Berlin
2003-2021
Freie Universität Berlin
2017-2021
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2010-2017
State of The Art
2010
University Medical Center
2004-2009
Universität Hamburg
2004
Neuroendocrine tumors (NETs) of the gastroenteropancreatic (GEP) system comprise a rare but challenging group malignant neoplasms and occur at virtually any site GEP system. In 2006, new TNM classification was proposed for staging grading upper NETs.The prognostic relevance analyzed retrospectively in 202 patients from referral center with histologically proven foregut NET. Patients were classified according to previous systems classification. Survival data acquired statistical analyses...
Neuroendocrine tumours (NET) of the gastroenteropancreatic system comprise a malignant entity with low incidence. Only limited information is available on long-term clinical outcome and clinically applicable prognostic factors. We performed retrospective analysis large, well-characterized centre-based patient cohort 399 patients histologically proven NET. Data were analysed according to epidemiological, histopathological characteristics. Detailed survival analyses using Kaplan–Meier method...
For risk assessment in primary prevention of cardiovascular disease, different charts are used for high-risk and low-risk countries. The objective the present study was to analyse current regional variation mortality within Europe.Age-standardized rates were calculated ischaemic heart disease (IHD) cerebrovascular (CVD) from data provided by Eurostat National Statistical Offices respective countries (2000). age-standardization, European standard population (1976) taken. Rates both on a...
Abstract BACKGROUND: Prognostic classification of neuroendocrine tumor (NET) patients is difficult due to the complexity current systems. A recent proposal for a tumor‐node‐metastasis (TNM) and grading system based on proliferative fraction proved valid in NETs foregut origin. The purpose this study was test efficacy TNM staging midgut hindgut NETs. METHODS: Two hundred seventy with histologically proven were investigated. Epidemiological, clinicopathological, tumor‐specific data at initial...
In the diagnosis of obstructive coronary artery disease (CAD), computed tomography (CT) is an accurate, noninvasive alternative to invasive angiography (ICA). However, comparative effectiveness CT and ICA in management CAD reduce frequency major adverse cardiovascular events uncertain.We conducted a pragmatic, randomized trial comparing with as initial diagnostic imaging strategies for guiding treatment patients stable chest pain who had intermediate pretest probability were referred at one...
To investigate whether a shorter health status instrument, the short form (SF)-12, is comparable with its longer version, SF-36, for measuring related quality of life patients coronary heart disease.Prospective cohort study follow up at six and 12 months.18 cardiac rehabilitation centres in Germany.Patients were enrolled admission to after myocardial infarction, artery bypass grafting, percutaneous transluminal angioplasty.Correlation coefficients calculated between SF-12 SF-36 physical...
Das Lungenkarzinom ist mit jährlich über 40 000 Sterbefällen in der Bundesrepublik Deutschland die vierthäufigste Todesursache und häufigste Krebstodesursache [1]. Trotz Fortschritte Diagnostik Therapie liegt 5-Jahres-Überlebensrate Patienten europäischen nordamerikanischen Ländern nur einem Bereich von 5,5 – 15,7 % [2] [3]. Ziel vorliegenden Leitlinie Verbesserung Prognose Lebensqualität Lungenkarzinomen durch Optimierung des Einsatzes derzeitigen diagnostischen therapeutischen...
This abridged version is based on an interdisciplinary guideline which corresponds to development stage 3 (S3) of guidelines according the classification Association Scientific Medical Societies in Germany (AWMF). The process characterized by combination formal evidence-search, consensus, logic (algorithms), decision and outcome analysis, with cooperation 15 German Austrian medical societies. [Table 1] shows relationship between levels evidence, resulting recommendation grades...
Human Papillomavirus (HPV) is a common sexually transmitted infection and aetiologically linked with number of health problems. In Germany, HPV vaccination for cervical cancer prevention recommended girls aged 12-17 years since 2007; however, coordinated national immunization programme does not exist. We assessed whether socio-demographic factors sexual history are associated awareness the vaccine, vaccine uptake HPV-related knowledge among young women men.In 2010, survey was conducted 18-...
Sudden infant death syndrome (SIDS) continues to be one of the main causes mortality in United States. The objective this study was analyse association between diphtheria-tetanus-pertussis (DTP) immunisation and SIDS over time.
Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role symptomatic patients is less clear. Purpose To assess the of CAC scoring MACE participants with stable chest pain initially referred invasive coronary angiography (ICA). Materials and Methods This prespecified subgroup analysis from Diagnostic Imaging Strategies Patients With Stable Chest Pain Intermediate Risk Artery Disease (DISCHARGE)...
Increased knowledge of stroke risk factors in the general population may lead to improved prevention stroke. The objective present study was assess and determine associated with knowledge.In a population-based survey, we sent questionnaire randomly selected residents Berlin who were > or =50 years age enquiring about factors. Knowledge assessed an open-ended question. In addition, enquired source participants' information. Sociodemographic factors, including age, sex, educational level,...
Objective To analyse the role and meaning of health information in individuals’ experiences with either breast, colorectal or prostate cancer order to better understand unmet needs people a diagnosis. Design This is secondary analysis data from qualitative interview study including narrative interviews maximum variation sampling. A thematic was conducted, followed by an in-depth based on principles grounded theory. Setting Interviewees were sought across Germany through self-help...
Abstract Purpose The aim of our study was to explore the impact COVID-19 pandemic on reported cancer cases in Bavaria, Germany, by comparing pre-pandemic (March 2019 February 2020) and period 2020 2021). Methods Data incident were retrieved from Bavarian Cancer Registry (until 22nd April 2022). We included patients with malignant situ neoplasms pathology departments consistent reporting. calculated number during 95% confidence intervals (CI) Bonferroni correction (α = 0.0018) based a Poisson...
Die vorliegende Kurzfassung basiert auf einer interdisziplinären Leitlinie, die der Entwicklungsstufe 3 (S3) Leitlinien nach Klassifikation Arbeitsgemeinschaft Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) entspricht und durch Kombination von formaler Evidenz-Recherche, Konsensfindung, Logik (Algorithmen), Entscheidungs- Outcome-Analyse sowie interdisziplinärem Abgleich unter Beteiligung 15 deutschen österreichischen medizinischen gekennzeichnet ist. [Tab. 1] zeigt Beziehung...
Understanding peoples' evaluations of their health care is important to ensure appropriate health-care services.To understand what factors influence satisfaction with and how interpersonal trust established between doctors cancer patients in Germany.A narrative interview study that included women a diagnosis breast men prostate cancer. A question-focused analysis was conducted.Interviewees were sought across Germany through self-help organizations, clinics, rehabilitation facilities,...
Within Europe, a pronounced geographical gradient of mortality from ischaemic heart disease has been observed with the highest burden in north east and lowest south west. The study objective was to compare between former East West Germany since reunification.Analyses age standardised rates (ICD-9 410-414, ICD-10 I20-I25) 1990-1991 2000.Former Germany.After peak early 1990s, substantially declined both parts (from 222 169 per 100 000 150 116 West). regional difference, however, remained...
In patients with acute stroke, systemic thrombolysis needs to be administered within 3 hours of symptom onset. The aim the present study was reduce prehospital delays in a population-based intervention.We performed cluster-randomized trial 48 zip code areas as cluster units catchment area inner-city hospitals Berlin, Germany. primary end point time between onset and hospital admission. intervention consisted an educational letter indicating stroke symptoms emphasizing importance calling...
In industrialized countries, acute infectious enteric diseases are usually mild, but they can also cause death. They do so, however, at different ages. Using 2004-2008 German notification data, we computed and compared crude premature mortality [three measures of years potential life lost (YPLL)] illnesses caused by Campylobacter spp., Listeria monocytogenes, norovirus, rotavirus, non-typhoidal Salmonella Shiga toxin-producing E. coli (STEC). Among ~1.5 million notified illnesses, those...