- Veterinary Medicine and Surgery
- Diet and metabolism studies
- Human-Animal Interaction Studies
- Adipose Tissue and Metabolism
- Veterinary Equine Medical Research
- Reproductive Physiology in Livestock
- Veterinary Orthopedics and Neurology
- Diabetes and associated disorders
- Muscle metabolism and nutrition
- Hormonal and reproductive studies
- Gut microbiota and health
- Ruminant Nutrition and Digestive Physiology
- Clostridium difficile and Clostridium perfringens research
- Pharmacological Effects and Assays
- Veterinary Pharmacology and Anesthesia
- Probiotics and Fermented Foods
- Pancreatic function and diabetes
- Sperm and Testicular Function
- Diabetes Management and Research
- Regulation of Appetite and Obesity
- Metabolism and Genetic Disorders
- Streptococcal Infections and Treatments
- Animal Behavior and Welfare Studies
- Veterinary Oncology Research
- Adipokines, Inflammation, and Metabolic Diseases
Swedish University of Agricultural Sciences
2015-2025
Novo Nordisk (Denmark)
2015
Sequencing of candidate genes for obesity in Labrador retriever dogs identified a 14 bp deletion pro-opiomelanocortin (POMC) with an allele frequency 12%. The disrupts the β-MSH and β-endorphin coding sequences is associated body weight (per effect 0.33 SD), adiposity, greater food motivation. Among other dog breeds, was only found closely related flat-coat (FCR), where it similarly mutation significantly more common retrievers selected to become assistance than pets. In conclusion, POMC...
Obesity is a common nutrition-related disorder leading to reduced life expectancy in both humans and dogs. With the aim of identifying new prevention control options, study objectives were (1) investigate dog-owner perceptions about obesity terms themselves their dogs, (2) identify factors associated with possible social, environmental economic drivers for its development dog owners pets. A cross-sectional questionnaire-based was performed across multiple countries. The questionnaire focused...
Objective This study aimed to assess intra- and inter-observer reliability of neck, chest, abdominal girth measurements in dogs compare these made with a measuring tape, equipped or without dynamometer. Methods The locations the middle cranial widest caudal abdomen were measured individually by two observers 16 standing squarely at an examination table. Girth performed triplicate other observer recording data. All underwent evaluation using tape spring dynamometer, while subgroup ( n = 8)...
Previous studies using tympanic thermometers on pets have presented inconsistent conclusions. The first aim of the current study was to compare assessed temperatures and rectal healthy cats in a home environment admitted clinical care. second stress (Fear, Anxiety Stress scale, FAS) during measurements. non-clinical sample included 25 cats, 36 cats. FAS score (mean ± SD) significantly higher (p < 0.0001) measurements (2.9 0.9) than in-ear (1.6 0.9), temperature both right left ears bias...
Overweight in dogs is an increasing problem, with a prevalence of about 30% Sweden. To prevent the negative health effects overweight, it important to identify and treat canine overweight. Dog owners are essential for such interventions. The aim this study was evaluate dog owners' perceptions various body compositions via indirect assessment based on photos direct their own dogs. A second effect standardized practical education condition score (BCS) 9-point BCS scale used, two samples were...
Measurement of low concentrations C-reactive protein (CRP) in dogs has previously been performed with nonautomated assays. The aim this study was to validate an automated high-sensitivity CRP (hsCRP) assay, developed by modifying a routinely used canine-specific immunoturbidimetric test (cCRP). Imprecision, linearity under dilution, limit blank (LOB), detection (LOD), and quantification (LOQ) were determined for the hsCRP test, as well presence prozone effect interferences. imprecision,...
The gut microbiota and its metabolic end-products act in close collaboration with the nutrient metabolism of animal. A relationship between excess adiposity alterations composition has been identified humans rodents, but data are scarce for overweight dogs. This study compared temporal variations healthy lean spontaneously analysis was based on three individual fresh faeces samples from each dog during a 10-day period. Twenty-seven intact male Labrador retriever dogs were included, 12 which...
The prevalence of overweight is increasing in dogs, but the metabolic events related to this condition are still poorly understood. purpose study was investigate postprandial response plasma metabolites using a meal-challenge test and identify variations spontaneous overweightness privately owned dogs. Twenty-eight healthy male intact Labrador Retriever dogs were included, 12 which classified as lean (body score (BCS) 4–5 on 9-point scale) 16 (BCS 6–8). After an overnight fast (14–17 h),...
Background Obese dogs risk poor life quality, creating a need for increased knowledge of metabolism in overweight dogs. Objectives Investigate postprandial metabolic and hormonal responses to high‐fat mixed‐meal lean versus Animals Twenty‐eight healthy intact male Labrador Retrievers were included. Methods Prospective observational study. Twelve grouped as (body condition score ( BCS 4–5), 10 slightly 6), 6 6.5–8) on 9‐point scale. After an overnight fast, urine blood samples collected. Dogs...
Obesity in dogs is an increasing problem and better knowledge of the metabolism overweight needed. Identification molecular changes related to may lead new methods improve obesity prevention treatment. The aim study was firstly investigate whether Nuclear Magnetic Resonance (NMR) based metabolomics could be used differentiate postprandial from fasting urine dogs, secondly metabolite profiles differ between lean urine, respectively. Twenty-eight healthy intact male Labrador Retrievers were...
Background A hyperbolic relationship between β‐cell response and insulin sensitivity ( IS ) has been described in several species including rodents, dogs, humans. This not elucidated the horse. Hypothesis/Objectives To determine whether exists horses by using indices of from oral sugar test OST measurements euglycemic hyperinsulinemic clamp EHC ). second aim was to compare how well estimates correlate. Animals Forty‐nine with different degrees regulation (normal‐to‐severe dysregulation)....
Increasing levels of physical inactivity is a global burden for mankind and also an emerging problem in companion dogs. In both humans dogs, insufficient activity associated with increased risk noncommunicable diseases impaired quality life (QoL). The aim the current pilot study was to evaluate effects joint outdoor exercise program dog owners (n = 22) dogs focus on QoL body measurements. Results indicate that eight-week intervention alone, target distance at least 2 km twice week, may be...
Systemic hypertension is a prominent feature in humans with metabolic syndrome (MS) and this partly caused by an enhanced endothelin-1 (ET-1) mediated vasoconstriction. There are indications that systemic might be equine (EMS) but if ET-1 involved the development of horses not known. Increased levels cortisol have also been found MS there no reports horses. Before blood pressure, plasma serum can evaluated EMS, it necessary to investigate interday variation these parameters on clinically...
Obesity in dogs is an increasing problem associated with morbidity, shortened life span and poor quality. Overweight exhibit postprandial hyperlipidaemia, highlighting the need to identify potential dysregulations lipid metabolism. This study investigated metabolites related metabolism (i.e. acylcarnitines taurine) phospholipids a feed-challenge test aimed metabolic variations spontaneously overweight dogs. Twenty-eight healthy male Labrador Retriever were included, 12 of which classified as...
Abstract Background The prevalence of overweight and obesity is increasing in companion dogs, but little known these conditions show dogs. This study assessed body condition score (BCS) dogs six selected popular breeds at a major Swedish dog event examined the association between BCS performance competition. Results At one Sweden’s largest shows, 120 different was by trained animal healthcare personnel, using 9-point scale with conditional cut-off for set to ≥ 6. Prevalence cohort 32% all...
Abstract Background Research on the effects of physical exercise canine body composition is limited. The aim this study was to investigate a programme bodyweight, condition score (BCS) and chest, abdominal thigh circumferences in dogs. Twenty-one healthy dogs different breeds exercised together with their owners during an eight-week consisting jogging strength exercises. Standardised measurements were performed triplicates measuring tape standing Chest circumference measured at three...
Anti-Mullerian hormone (AMH) and testosterone are produced by the testicles. Both hormones affect sperm production, hence fertility. In men with a high body condition score (BCS), concentration is low.
Obesity in dogs has been associated with both increased and decreased blood C-reactive protein (CRP) concentrations.