A5067423369- Cytokine Signaling Pathways and Interactions
- Cancer Cells and Metastasis
- Estrogen and related hormone effects
- Immune cells in cancer
- NF-κB Signaling Pathways
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- Bioinformatics and Genomic Networks
- Food Safety and Hygiene
- Milk Quality and Mastitis in Dairy Cows
- Cancer Research and Treatments
- Genomics, phytochemicals, and oxidative stress
- Nuclear Receptors and Signaling
- IL-33, ST2, and ILC Pathways
- Cancer, Hypoxia, and Metabolism
- Plant Pathogenic Bacteria Studies
- Cancer Immunotherapy and Biomarkers
University of Trento
2019-2023
Vilnius University
2020-2022
Cancer Genetics (United States)
2020
The transcription factor ETV7 is an oncoprotein that up-regulated in all breast cancer (BC) types. We have recently demonstrated promoted progression by increasing cell proliferation and stemness was also involved the development of chemo- radio-resistance. However, roles inflammation yet to be studied. Gene ontology analysis previously performed on BC cells stably over-expressing suppression innate immune inflammatory responses. To better decipher involvement these signaling pathways, this...
Abstract Cancer stem cells (CSCs) represent a population of within the tumor able to drive tumorigenesis and known be highly resistant conventional chemotherapy radiotherapy. In this work, we show new role for ETV7, transcriptional repressor member ETS family, in promoting breast cancer stem-like plasticity resistance chemo- radiotherapy (BC) cells. We observed that MCF7 T47D BC-derived stably over-expressing ETV7 showed reduced sensitivity chemotherapeutic drug 5-fluorouracil radiotherapy,...
Abstract We present a new model of ESR1 network regulation based on analysis Doxorubicin, Estradiol, and TNFα combination treatment in MCF-7. used Doxorubicin as therapeutic agent, marker mediator an inflammatory microenvironment 17β-Estradiol (E2) agonist Estrogen Receptors, known predisposing factor for hormone-driven breast cancer, whose pharmacological inhibition reduces the risk cancer recurrence. Based results transcriptomics analysis, we found 71 differentially expressed genes that...
Abstract The transcription factor ETV7 is an oncoprotein that up-regulated in all breast cancer (BC) types. We have recently demonstrated promoted progression by increasing cell proliferation and stemness was also involved the development of chemo- radio-resistance. However, roles inflammation yet to be studied. Gene ontology analysis previously performed on BC cells stably over-expressing suppression innate immune inflammatory responses. To better decipher involvement these signaling...
Abstract The transcription factor ETV7 is an oncoprotein that up-regulated in all breast cancer (BC) types. We have recently demonstrated promoted progression by increasing cell proliferation and stemness was also involved the development of chemo- radio-resistance. However, roles inflammation yet to be studied. Gene ontology analysis previously performed on BC cells stably over-expressing suppression innate immune inflammatory responses. To better decipher involvement these signaling...