A5001466457- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Neuroscience and Neural Engineering
- EEG and Brain-Computer Interfaces
- Neuroscience and Neuropharmacology Research
- Advanced MRI Techniques and Applications
- Photoreceptor and optogenetics research
- Epilepsy research and treatment
- Blind Source Separation Techniques
- Atomic and Subatomic Physics Research
- Reading and Literacy Development
- Electrical and Bioimpedance Tomography
- Heart Rate Variability and Autonomic Control
- Advanced Neuroimaging Techniques and Applications
- Memory and Neural Mechanisms
- Neurobiology of Language and Bilingualism
- Neural and Behavioral Psychology Studies
- Optical Imaging and Spectroscopy Techniques
- Advanced Memory and Neural Computing
- Neuroscience of respiration and sleep
- Geophysical Methods and Applications
- Wireless Body Area Networks
- Molecular Communication and Nanonetworks
- Medical Imaging Techniques and Applications
- Visual perception and processing mechanisms
Florida International University
2015-2025
Universitätsklinikum Gießen und Marburg
2024
Tohoku University
2007-2019
Centre de Recherche en Neurosciences de Lyon
2011
University of Havana
2002
Cuban Neuroscience Center
1991-2000
Baycrest Hospital
1997
Centro Nacional de Investigaciones Científicas
1992
Over the last decade, several papers have focused on construction of highly detailed mouse high field magnetic resonance image (MRI) templates via non-linear registration to unbiased reference spaces, allowing for a variety neuroimaging applications such as robust morphometric analyses. However, work in rats has only provided medium MRI averages based linear biased spaces with sole purpose approximate functional (fMRI) localization. This precludes any analysis spite need exploring detail...
LBA4001 Background: The IKF-575 trial investigates the long-standing question about role of surgical intervention in limited-metastatic gastric / esophagogastric junction cancer after systemic induction therapy. Methods: Previously untreated patients (pts) with limited metastatic disease (retroperitoneal lymph node (RPLN) metastases only or a maximum one incurable organ site that is potentially resectable locally controllable without retroperitoneal nodes) received 4 cycles FLOT, +...
We used a real-skull phantom head to investigate the performances of representative methods for EEG source localization when considering various models. describe several experiments using montage with current sources located at multiple positions and orientations inside human skull filled conductive medium. The robustness selected based on distributed models is evaluated as solutions forward problem (from sphere finite element method) are considered. Experimental results indicate that...
For about six decades, primary current sources of the electroencephalogram (EEG) have been assumed dipolar in nature. In this study, we used electrophysiological recordings from anesthetized Wistar rats undergoing repeated whisker deflections to revise biophysical foundations EEG model. a first experiment, performed three-dimensional extracellular potentials large portion barrel field estimate intracortical multipolar moments generated either by single spiking neurons (i.e., pyramidal cells,...
Microelectrode arrays used to record local field potentials from the brain are being built with increasingly more spatial resolution, ranging initially developed laminar those planar and three-dimensional (3D) formats. In parallel such development in recording techniques, current source density (CSD) analyses have recently been expanded up continuous-3D form. Unfortunately, effect of conductivity profile on CSD analysis performed contemporary microelectrode has not yet evaluated most studies...
It is generally recognised that event related potentials (ERPs) of electroencephalogram (EEG) primarily reflect summed post-synaptic activity the local pyramidal neural population(s). However, it still not understood how positive and negative deflections (e.g. P1, N1 etc) observed in ERP recordings are to underlying excitatory inhibitory activity. We investigated neurogenesis P1 ERPs by pharmacologically manipulating somatosensory cortex rodent, concurrently recording EEG field (LFPs). found...
In this study, we investigated two aspects of verb processing: first, whether verbs are processed differently from nouns; and second, how verbal morphology is processed. For purpose, used functional magnetic resonance imaging to compare three types lexical processing in Japanese: the nouns, unmarked active verbs, inflected passive verbs. Twenty-eight healthy subjects were shown a item asked judge presented was legal word. Although all conditions activated bilateral inferior frontal,...
Abstract Here we present a detailed biophysical model of how brain electrical and vascular dynamics are generated within basic cortical unit. The was obtained from coupling canonical neuronal mass an expandable vasculature. In this proposal, address several aspects related to electroencephalographic functional magnetic resonance imaging data fusion: (1) the impact cerebral architecture (at different physical levels) on observations; (2) physiology involved in electrovascular coupling; (3)...
Vasoactive signaling from astrocytes is an important contributor to the neurovascular coupling (NVC), which aims at providing energy neurons during brain activation by increasing blood perfusion in surrounding vasculature. Pharmacological manipulations have been previously combined with experimental techniques (e.g., transgenic mice, uncaging, and multiphoton microscopy) stimulation paradigms isolate
LBA248 Background: Effective treatment options remain an unmet need for patients (pts) with microsatellite stable/mismatch repair proficient (MSS/pMMR) metastatic colorectal cancer (mCRC). Combination therapy the anti–lymphocyte activation gene (LAG)-3 antibody favezelimab (fave) and PD-1 inhibitor pembrolizumab (pembro), has shown promising antitumor activity manageable safety in PD-L1 CPS ≥1 MSS/pMMR mCRC. The phase 3 KEYFORM-007 study (NCT05064059) evaluated efficacy of co-formulated...
Abstract In the companion article a local electrovascular coupling (LEVC) model was proposed to explain continuous dynamics of electrical and vascular states within cortical unit. These produce certain mesoscopic reflections whose discrete time series can be reconstructed from electroencephalography (EEG) functional magnetic resonance imaging (fMRI). this we develop recursive optimization algorithm based on linearization (LL) filter an innovation method make statistical inferences about LEVC...
The elucidation of the complex machinery used by human brain to segregate and integrate information while performing high cognitive functions is a subject imminent future consequences. most significant contributions date in this field, known as neuroscience, have been achieved using innovative neuroimaging techniques, such electroencephalogram (EEG) functional magnetic resonance imaging (fMRI), which measure variations both time space some interpretable physical magnitudes. Extraordinary...