- Topic Modeling
- Artificial Intelligence in Healthcare and Education
- Birth, Development, and Health
- Machine Learning in Healthcare
- Glaucoma and retinal disorders
- Ubiquitin and proteasome pathways
- Genomics and Chromatin Dynamics
- Pediatric Urology and Nephrology Studies
- Corneal surgery and disorders
- Electrolyte and hormonal disorders
- Chemical Safety and Risk Management
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Heavy Metal Exposure and Toxicity
- Ion Transport and Channel Regulation
- Retinal Imaging and Analysis
- Safe Handling of Antineoplastic Drugs
- Neonatal and fetal brain pathology
- Genetics, Aging, and Longevity in Model Organisms
- Natural Language Processing Techniques
- Plant Genetic and Mutation Studies
- Veterinary Medicine and Surgery
- Mercury impact and mitigation studies
- Pesticide Exposure and Toxicity
- Cancer-related Molecular Pathways
New York University
2021-2025
NYU Langone Health
2022
Michigan State University
2018-2019
John Cochran VA Medical Center
1978
Washington University in St. Louis
1978
Precise: In this article, we describe the development of validated software that automates cost-effectiveness analyses minimally invasive glaucoma surgeries based on modifications to robust mathematical models progression and management discussed in previous literature Purpose: To develop a application streamline use (CE) clinical investigations (MIGS) United States. Design: Automated cost-utility analysis adapted from Markov described prior literature. Participants: Patients ages 65 years...
The effects of acute unilateral ureteral obstruction (UUO) 18 h duration on deep nephron function was evaluated in 14 weanling rats with the technique micropuncture. After release UUO, 3.4 +/- 0.66% (SE) filtered water remained at tip collecting duct nearly fivefold greater than controls (0.75 0.10%). Similar differences were seen fractional sodium that this site. ratio tubular fluid osmolality to plasma also reduced UUO group (1.53 0.06 vs. 4.60 0.26 controls, P less 0.001). Single...
Juxtamedullary (JM) nephron and collecting duct function was studied after a two-thirds reduction in renal mass the young rat. The glomerular filtration rate of JM nephrons twofold greater remnant kidney (RK) group than controls, but this increase proportional to measured surface nephrons. Despite an absolute reabsorption, delivery sodium water end proximal tubule superficial bend Henle's loop increased. This consequence filtered load decrease fractional reabsorption. Potassium handling...
Abstract Importance Large language models (LLMs) are crucial for medical tasks. Ensuring their reliability is vital to avoid false results. Our study assesses two state-of-the-art LLMs (ChatGPT and LlaMA-2) extracting clinical information, focusing on cognitive tests like MMSE CDR. Objective Evaluate ChatGPT LlaMA-2 performance in CDR scores, including associated dates. Methods data consisted of 135,307 notes (Jan 12th, 2010 May 24th, 2023) mentioning MMSE, CDR, or MoCA. After applying...
Ensuring reliability of Large Language Models (LLMs) in clinical tasks is crucial. Our study assesses two state-of-the-art LLMs (ChatGPT and LlaMA-2) for extracting information, focusing on cognitive tests like MMSE CDR. data consisted 135,307 notes (Jan 12th, 2010 to May 24th, 2023) mentioning MMSE, CDR, or MoCA. After applying inclusion criteria 34,465 remained, which 765 underwent ChatGPT (GPT-4) LlaMA-2, 22 experts reviewed the responses. successfully extracted CDR instances with dates...
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Recollection micropuncture in Munich-Wistar rats was used to study the effects of intravenous hypertonic mannitol infusions on fluid reabsorption by surface nephrons, prior bend Henle's loop deep and along papillary collecting duct. During diuresis, single nephron glomerular filtration rate rose significantly nephrons but fell nephrons. Although increased delivery sodium water end proximal tubule first portion distal were reabsorbed between these two sites. In Henle decreased. Absolute this...
Retinoblastoma proteins are eukaryotic transcriptional corepressors that play central roles in cell cycle control, among other functions. Although most metazoan genomes encode a single retinoblastoma protein, gene duplications have occurred at least twice: the vertebrate lineage, leading to Rb, p107, and p130, Drosophila, an ancestral Rbf1 derived Rbf2 gene. Structurally, resembles p107 mutation of is lethal. more divergent does not lead lethality. However, retention >60 My Drosophila points...
Abstract Background Large language models (LLMs) provide powerful natural processing capabilities in medical and clinical tasks. Evaluating LLM performance is crucial due to potential false results. In this study, we assessed ChatGPT Llama2, two state‐of‐the‐art LLMs, extracting information from notes, focusing on cognitive tests, specifically the Mini Mental State Exam (MMSE) Cognitive Dementia Rating (CDR). Method We compiled a dataset consisting of 765 notes mentioning MMSE CDR. 22...
Abstract Retinoblastoma proteins are eukaryotic transcriptional co-repressors that play central roles in cell cycle control, among other functions. Although most metazoan genomes encode a single retinoblastoma protein, gene duplications have occurred at least twice: the vertebrate lineage, leading to three genes encoding Rb, p107, and p130, while separately Drosophila lineage an ancestral Rbf1 derived Rbf2 gene. Structurally, resembles p107 p130 closely, mutation of is lethal, more...