A5065882706- Topic Modeling
- Ethics in medical practice
- Artificial Intelligence in Healthcare and Education
- Machine Learning in Healthcare
- Supercapacitor Materials and Fabrication
- Cardiac Valve Diseases and Treatments
- Electrocatalysts for Energy Conversion
- Proteoglycans and glycosaminoglycans research
- Injury Epidemiology and Prevention
- Torture, Ethics, and Law
- Fuel Cells and Related Materials
- Polysaccharides Composition and Applications
- SARS-CoV-2 and COVID-19 Research
- Cardiac Structural Anomalies and Repair
- Gun Ownership and Violence Research
- Traffic and Road Safety
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Heparin-Induced Thrombocytopenia and Thrombosis
- Reproductive Health and Contraception
- Biomimetic flight and propulsion mechanisms
- Tribology and Lubrication Engineering
- COVID-19 Clinical Research Studies
- Circadian rhythm and melatonin
- Nicotinic Acetylcholine Receptors Study
New York University
2021-2024
New England College of Optometry
2024
Optum (United States)
2024
Center for Practical Bioethics
2023
Harvard University
2023
Brown University
2023
Massachusetts Eye and Ear Infirmary
2023
Smith-Kettlewell Eye Research Institute
2023
Royal Military College of Canada
2022
Oregon National Primate Research Center
2021
The recapitulation of the material properties and structure native aortic valve leaflet, specifically its anisotropy laminate structure, is a major design goal for scaffolds heart tissue engineering. Poly(ethylene glycol) (PEG) hydrogels are attractive this purpose as they biocompatible, can be modified their mechanical biofunctional properties, laminated. This study investigated augmenting PEG with polycaprolactone (PCL) an analog to fibrosa improve strength introduce anisotropic behavior....
Abstract Importance Large language models (LLMs) are crucial for medical tasks. Ensuring their reliability is vital to avoid false results. Our study assesses two state-of-the-art LLMs (ChatGPT and LlaMA-2) extracting clinical information, focusing on cognitive tests like MMSE CDR. Objective Evaluate ChatGPT LlaMA-2 performance in CDR scores, including associated dates. Methods data consisted of 135,307 notes (Jan 12th, 2010 May 24th, 2023) mentioning MMSE, CDR, or MoCA. After applying...
Ensuring reliability of Large Language Models (LLMs) in clinical tasks is crucial. Our study assesses two state-of-the-art LLMs (ChatGPT and LlaMA-2) for extracting information, focusing on cognitive tests like MMSE CDR. data consisted 135,307 notes (Jan 12th, 2010 to May 24th, 2023) mentioning MMSE, CDR, or MoCA. After applying inclusion criteria 34,465 remained, which 765 underwent ChatGPT (GPT-4) LlaMA-2, 22 experts reviewed the responses. successfully extracted CDR instances with dates...
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Despite decades of clinical use and research, the mechanism action (MOA) antidepressant medications remains poorly understood. Selective serotonin reuptake inhibitors (SSRIs) serotonin-norepinephrine (SNRIs) are most commonly prescribed antidepressants—atypical antidepressants such as bupropion have also proven effective, while exhibiting a divergent phenotype. The difference in phenotypic profiles presumably lies differences among MOAs SSRIs/SNRIs bupropion. We integrated ensemble...
Abstract Background Large language models (LLMs) provide powerful natural processing capabilities in medical and clinical tasks. Evaluating LLM performance is crucial due to potential false results. In this study, we assessed ChatGPT Llama2, two state‐of‐the‐art LLMs, extracting information from notes, focusing on cognitive tests, specifically the Mini Mental State Exam (MMSE) Cognitive Dementia Rating (CDR). Method We compiled a dataset consisting of 765 notes mentioning MMSE CDR. 22...
The debate over whether the medical profession should accommodate its members' conscientious objections (COs) has raged on in bioethics literature and legislative floors for decades. Unfortunately, participants all sides of fail to distinguish among different types CO, a failure that obstructs view which cases warrant accommodation why. In this paper, we identify one type CO warrants consideration accommodation, called Nature Medicine COs (NoMCOs). NoMCOs involve refusal physicians perform...
Central administration of fibroblast growth factor-1 (FGF1) results in long-lasting resolution hyperglycemia various rodent models, but the pre- and postsynaptic mechanisms mediating central effects FGF1 are unknown. Here we utilize electrophysiology recordings from neuronal populations arcuate nucleus hypothalamus (ARH), solitary tract (NTS), area postrema (AP) to investigate underlying actions. While did not alter membrane potential ARH-NPY-GFP neurons, it reversibly depolarized 83%...
The application of dynamic soaring techniques on small unmanned aerial vehicles (SUAVs) aims to exploit naturally occurring wind gradients increase flight endurance. However, considering the limited computational resources onboard SUAVs and imperfect nature real-world environments physical systems, there is a practical need design simple robust control systems. As such, this paper presents neuroevolutionary strategy for generating efficient neurocontrollers that exhibit generalized behavior....
Carbon aerogel possesses unique structural and electrical properties, such as high mesopore volume, specific surface area, conductivity, which make it suitable for use a catalyst support in Proton Exchange Membrane Fuel Cells (PEMFC). In this study, we present novel synthesis of highly mesoporous carbon via ambient-drying investigate its application PEMFCs. The effects activation on were also studied. TEM, XRF, Non Localized Density Function Theory (NLDFT) BJH analysis carried out to observe...
Abstract The spongiosa is the middle of three layers aortic valve leaflet and contains proteoglycan (PG) versican glycosaminoglycan (GAG) hyaluronan (HA) in large quantities. resulting versican-HA aggregates allow layer to retain quantities water, giving a gel-like consistency. This least understood as it pertains its role valvular function mechanics. However, GAGs this are perceived be important function, loss bioprosthetic heart valves coincides with failure. functions attributed these...
<p>Carbon aerogel possesses unique structural and electrical properties, such as high mesopore volume, specific surface area, conductivity, which make it suitable for use a catalyst support in Proton Exchange Membrane Fuel Cells (PEMFC). In this study, we present novel synthesis of highly mesoporous carbon via ambient-drying investigate its application PEMFCs. The effects activation on were also studied. TEM, XRF, Non Localized Density Function Theory (NLDFT) BJH analysis carried out...
Whether the medical profession should accommodate conscientious objections (COs) remains an open question. I believe that doctors’ COs be accommodated only when they are derived from their commitments about nature of medicine (i.e., no doctor qua perform objected-to service), and ought to these in order maintain a system-level capacity for moral progress self-correction [1]. The purpose this project is explore how, if at all, my conception Nature Medicine reform-based argument accommodation...