Matthew Hagan

ORCID: 0000-0003-4130-3430
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Emergency and Acute Care Studies
  • Intracranial Aneurysms: Treatment and Complications
  • Vascular Malformations Diagnosis and Treatment
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Pelvic and Acetabular Injuries
  • Spinal Cord Injury Research
  • Advanced Malware Detection Techniques
  • Trauma and Emergency Care Studies
  • Spinal Dysraphism and Malformations
  • Patient Satisfaction in Healthcare
  • Security and Verification in Computing
  • Intestinal and Peritoneal Adhesions
  • Neurosurgical Procedures and Complications
  • Cerebrospinal fluid and hydrocephalus
  • Trauma Management and Diagnosis
  • Cervical and Thoracic Myelopathy
  • Hospital Admissions and Outcomes
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Library Collection Development and Digital Resources
  • Cardiac, Anesthesia and Surgical Outcomes
  • Dialysis and Renal Disease Management
  • Quantum Computing Algorithms and Architecture
  • Venous Thromboembolism Diagnosis and Management

University of Toronto
2023

Brown University
2020-2023

University of Chicago
2022-2023

Neurological Surgery
2022-2023

Providence College
2022

Rhode Island Hospital
2022

Temple University
2017-2020

University of Miami
2020

University of Kansas
2020

Northwell Health
2020

Abstract The early neuropathological features of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) are protein aggregates in motor neurons and microglial activation. Similar pathology characterizes Guamanian ALS/Parkinsonism dementia complex, which may be triggered by the cyanotoxin β-N-methylamino-l-alanine (BMAA). We report here occurrence ALS/MND-type pathological changes vervets (Chlorocebus sabaeus; n = 8) fed oral doses a dry powder BMAA HCl salt (210 mg/kg/day) for 140...

10.1093/jnen/nlaa002 article EN cc-by Journal of Neuropathology & Experimental Neurology 2020-01-21

In this paper we provide a framework for combining multiple quantum simulation methods, such as Trotter-Suzuki formulas and QDrift into single Composite channel that builds upon older coalescing ideas reducing gate counts. The central idea behind our approach is to use partitioning scheme allocates Hamiltonian term the Trotter or part of within simulation. This allows us simulate small but numerous terms using while simulating larger high-order formula. We prove rigorous bounds on diamond...

10.22331/q-2023-11-14-1181 article EN cc-by Quantum 2023-11-14

Abstract Background: Cavernous angiomas (CAs) affect 0.5% of the population, predisposing to serious neurologic sequelae from brain bleeding. A leaky gut epithelium associated with a permissive microbiome, was identified in patients who develop CAs, favoring lipid polysaccharide producing bacterial species. Micro-ribonucleic acids along plasma levels proteins reflecting angiogenesis and inflammation were also previously correlated CA symptomatic hemorrhage. Methods: The metabolome hemorrhage...

10.1038/s43856-023-00265-1 article EN cc-by Communications Medicine 2023-03-03

Background: Large decompressive craniectomies may be life-saving; however, they also result in syndrome of the trephined. This postrecovery sequela is characterized by dizziness, fatigue, depression, weakness, speech slowing, gait disturbance, and impaired mentation. Because this entity poorly understood, authors attempted to quantify functional improvement patients with trephined after cranial vault reconstruction. Methods: Patients defects (>50 cm 2 ) from trauma, meningioma, hemorrhage...

10.1097/prs.0000000000006836 article EN Plastic & Reconstructive Surgery 2020-03-20

BackgroundIn the context of increased attention afforded to hospital efficiency and improved but safe patient throughput, decreasing unnecessary length stay (LOS) is imperative. Given that lumbar spine procedures may be among a hospital's most profitable services, identifying patients at risk healthcare resource utilization prior surgery valuable opportunity develop targeted pre- peri-operative intervention quality improvement initiatives. The purpose present investigation was examine...

10.1016/j.xnsj.2022.100187 article EN cc-by-nc-nd North American Spine Society Journal (NASSJ) 2022-11-25

Spinal cord injury (SCI) is a debilitating neurologic disorder that can result in significant morbidity and mortality, as well long term disability. Pediatric spinal injuries account for only 5% of all injuries. Understanding differences anatomic epidemiologic characteristics between pediatric adult SCI paramount to the accurate evaluation, diagnosis, treatment this potentially pathology. Standardized neurological examination dedicated spine imaging guide optimal management. For both...

10.1016/j.inat.2022.101594 article EN cc-by-nc-nd Interdisciplinary Neurosurgery 2022-05-31

Division of Plastic and Reconstructive Surgery, Temple University, Philadelphia, PA. Address correspondence reprint requests to Matthew Hagan, MD, James P. Bradley, 3401 N Broad Street, PA 19140; E-mail: [email protected]; protected] Received 14 September, 2016 Accepted 18 February, 2017 The authors report no conflicts interest.

10.1097/scs.0000000000003747 article EN Journal of Craniofacial Surgery 2017-06-02

The Internet of Things (IoT) holds great potential for productivity, quality control, supply chain efficiencies and overall business operations.However, with this broader connectivity, new vulnerabilities attack vectors are being introduced, increasing opportunities systems to be compromised by hackers targeted attacks.These pose severe threats a myriad IoT applications within areas such as manufacturing, healthcare, power energy grids, transportation commercial building management.While...

10.1049/cp.2018.0010 article EN 2018-01-01

The aim of this study was to describe a minimally invasive transforaminal surgical technique for treating awake patients presenting with lumbar radiculopathy and compressive facet cysts.Awake endoscopic decompression surgery performed in 645 over 6-year period from 2014 2020. Transforaminal utilizing high-speed drill 25 who had cysts. All surgeries were as outpatient procedures patients. Nine the previously undergone laminectomies at treated level. A retrospective chart review...

10.3171/2022.6.spine22451 article EN Journal of Neurosurgery Spine 2022-08-19

Diagnosis, pathophysiology, and rationale for surgical intervention in adult-onset tethered cord syndrome (ATCS) remain controversial. In this population, comorbid degenerative spinal disease (DSD) prior trauma may sometimes distract from radiologic evidence of TCS. We retrospectively reviewed electronic medical records consecutive patients (2011–2019) presenting with back pain, lower extremity neurological symptoms, and/or urinary or bowel who had fatty filum terminale (FT) low-lying conus...

10.1016/j.inat.2023.101773 article EN cc-by Interdisciplinary Neurosurgery 2023-04-28

Background: Socioeconomic factors can bias clinician decision-making in many areas of medicine. Psychosocial characteristics such as diagnosis alcoholism, substance abuse, and major psychiatric disorder are emerging potential sources conscious unconscious bias. We hypothesized that these psychosocial factors, addition to socioeconomic may impact the decision operate on patients with a traumatic cervicothoracic fracture associated spinal cord injury (SCI). Methods: performed cohort analysis...

10.21037/jss-21-37 article EN Journal of Spine Surgery 2021-09-01

<h3>Background</h3> Due to its ultraminimally invasive nature, endoscopic spinal surgery is an attractive tool in oncologic care. To date, there has been no comprehensive review of this topic. The authors therefore present a thorough search the medical literature on techniques for oncology. <h3>Methods</h3> A systematic using PubMed was conducted following keywords: spine surgery, oncology, and tumors. <h3>Results</h3> Collectively, 19 cases described Endoscopic employed care patients with...

10.14444/8412 article EN The International Journal of Spine Surgery 2022-11-28
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