A5074847813- Sleep and related disorders
- Sleep and Wakefulness Research
- Circadian rhythm and melatonin
- Neuroscience of respiration and sleep
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Infant Development and Preterm Care
- Pain Mechanisms and Treatments
- Stress Responses and Cortisol
- Sleep and Work-Related Fatigue
- Musculoskeletal pain and rehabilitation
- Mind wandering and attention
- Psychosomatic Disorders and Their Treatments
- Migraine and Headache Studies
- Health, psychology, and well-being
- Mindfulness and Compassion Interventions
- Early Childhood Education and Development
- Obstructive Sleep Apnea Research
- Language Development and Disorders
- EEG and Brain-Computer Interfaces
Johns Hopkins Medicine
2022-2024
Johns Hopkins University
2022-2024
Abstract Study Objectives Opioid withdrawal is an aversive experience that often exacerbates depressive symptoms and poor sleep. The aims of the present study were to examine effects suvorexant on oscillatory sleep-electroencephalography (EEG) band power during medically managed opioid withdrawal, their association with severity symptoms. Methods Participants use disorder (N = 38: age-range:21–63, 87% male, 45% white) underwent 11-day buprenorphine taper, in which they randomly assigned (20...
Objective Poor sleep is common in inflammatory bowel disease (IBD) and may be associated with overall worse outcomes. While the sleep/IBD literature growing, data are often self-reported. Further, much of research using objective measures architecture, or pattern depth, rely on single-night assessments, which can questionable validity. Design Participants IBD healthy controls were recruited from Dartmouth-Hitchcock Medical Center as part a two-phase clinical trial. Sleep architecture was...
Patients with chronic pain disorders, including Temporomandibular Disorders (TMDs) endorse high levels of sleep disturbances, frequently reporting reduced quality. Despite this, little is known about the effect that daytime has on microstructure and macro-architecture sleep. Therefore, we aimed to examine extent which sensitivity, measured using quantitative sensory testing (QST), associated objective parameters following night, architecture power spectral density, in women TMD.
Abstract Introduction Approximately 60% of individuals with temporomandibular joint disorders (TMD) report sleep disturbance. Dysregulation the hypothalamic-pituitary-adrenocortical (HPA) system is common in TMD, but less known about effects stressor type on HPA response. The present study measured salivary cortisol reactivity to quantitative sensory testing (QST) and Trier Social Stress Test (TSST) a sample TMD patients. It was hypothesized that poor would amplify effect each reactivity....
Abstract Introduction Opioid withdrawal exacerbates depressive symptoms and poor sleep. Previous findings demonstrate suvorexant’s ameliorative effect on sleep disturbances during this period, but is unknown whether these changes also confer benefit for or symptoms. therefore, we aimed to examine the effects suvorexant oscillatory sleep-EEG power inpatient opioid withdrawal, their association with severity Methods Participants Use Disorder (N=38: age-range = 21-63years, 87% male, 45% white)...
Abstract Introduction Previous studies have demonstrated that long-term opioid use alters sleep architecture and continuity. Long-term therapy (LTOT) is common amongst people with chronic pain, yet the interrelations of pain among patients on LTOT are poorly understood. Methods We characterized low back (CLBP) (n=53) using wireless sleep-electroencephalography (EEG), ecological momentary assessment (EMA) in a naturalistic remote study. The relationships duration percentages rapid eye...
Sleep disturbances are posited to play a key role in the development of poor mental and physical health outcomes related early life adversity (ELA), part through effects on brain development. Language is critically important for developmental across lifespan, including academic achievement emotion regulation. Yet, very little research has focused dynamic contributions ELA, sleep, language outcomes. In this mini review, we summarize current pediatric literature independently connecting ELA...
Abstract Introduction: Patients with chronic pain experience a high prevalence of comorbid insomnia, which is associated functional impairment. Recent advances in sleep electroencephalography (sleep-EEG) may clarify the mechanisms that link and pain. In this clinical update, we outline current advancements sleep-EEG assessments for provide research recommendations. Results: Promising preliminary work suggests spectral bands, particularly beta, gamma, alpha, delta power, create candidate...
Adverse childhood experiences (ACEs) have been associated with worse sleep, but existing literature is limited by use of predominantly White samples, lack objective sleep measurement, and non-standardized questionnaires. We investigated associations between retrospectively reported ACEs in adulthood a sample 43 adults 20-53 years age, free from chronic conditions, Body mass index (BMI) ≥ 25 (Mean age = 33.14 [SD 10.05], 74% female, 54% Black). Sleep efficiency (SE), total time (TST), wake...
Chronic pain is prevalent in older adults. Treatment, especially with opioids, often ineffective and poses considerable negative consequences this population. To improve treatment, it important to understand why adults are at a heightened risk for developing chronic pain. Insomnia major modifiable factor that ubiquitous among can also lead systemic inflammation affective disturbance, both of which may further exacerbate conditions Endotoxin exposure be used as an experimental model...