A5078861435- Sleep and Wakefulness Research
- Sleep and related disorders
- Innovations in Medical Education
- Restless Legs Syndrome Research
- Parkinson's Disease Mechanisms and Treatments
- Obstructive Sleep Apnea Research
- Clinical Reasoning and Diagnostic Skills
- Sleep and Work-Related Fatigue
- Empathy and Medical Education
- Healthcare Systems and Technology
- Diversity and Career in Medicine
- Neuroscience of respiration and sleep
- Patient-Provider Communication in Healthcare
- EEG and Brain-Computer Interfaces
- Healthcare professionals’ stress and burnout
- Simulation-Based Education in Healthcare
- Telemedicine and Telehealth Implementation
- Intensive Care Unit Cognitive Disorders
- Circadian rhythm and melatonin
- Dysphagia Assessment and Management
- Innovative Teaching Methods
- Mind wandering and attention
- Advances in Oncology and Radiotherapy
- Noise Effects and Management
- Reflective Practices in Education
Johns Hopkins University
2015-2024
Johns Hopkins Medicine
2015-2024
Wake Forest University
2017-2024
Duke University
2018-2024
Kennedy Krieger Institute
2023-2024
University of Córdoba
2024
Howard County General Hospital
2024
Johns Hopkins Hospital
2008-2023
Mass General Brigham
2023
Brigham and Women's Hospital
2023
Study Objective:To determine if recently abstinent, heavy marijuana (MJ) users show differences in polysomnographic (PSG) measures compared with a drug-free control group.
Prior studies, all using SPECT techniques, failed to find any differences for dopamine transporter (DAT) in restless legs syndrome (RLS) subjects. The distinct pharmacokinetic properties associated with SPECT-determined DAT along rapid biodynamic changes may, however, have missed membrane-bound differences. current studies assessed real-time binding potentials (BP) striatum of RLS patients 11C-methylphenidate and PET techniques. medications were stopped at least 11 days prior the study....
To assess the validity of sleep architecture and continuity biomarkers obtained from a portable, multichannel forehead electroencephalography (EEG) recorder.Forty-seven subjects simultaneously underwent polysomnography (PSG) while wearing frontopolar EEG recording device (Sleep Profiler). The PSG recordings independently staged by 5 registered polysomnographic technologists were compared for agreement with autoscored before after expert review. night-to-night variability first night bias, 2...
Increased orexin/hypocretin signaling is implicated in opioid withdrawal, sleep disturbances, and drug-seeking behaviors. This study examined whether a dual-orexin receptor antagonist would improve withdrawal outcomes when compared with placebo during buprenorphine/naloxone taper. Thirty-eight participants use disorder were recruited to clinical research unit maintained on 8/2 16/4 mg of treatment for 3 days before being randomized 20 suvorexant ( n = 14), 40 12), or 12); 26 individuals...
Prior studies using positron emission tomography (PET) or single-photon computed techniques have reported inconsistent findings regarding differences between patients with restless legs syndrome (RLS) and control in the striatal dopamine-2 receptor (D2R) binding potentials (BP). D2R-BP does reflect receptor-ligand interactions such as affinity (K(d)) density (β(max)) neurotransmitter synaptic concentrations. Thus, changes these primary factors. PET are currently available to estimate D2R...
To evaluate the validity of an ambulatory electroencephalographic (EEG) monitor for estimation sleep continuity and architecture in healthy adults.Healthy, good sleeping participants (n = 14) were fit with both EEG (Sleep Profiler) a full polysomnography (PSG) montage. recordings gathered from devices on same night, during which was permitted uninterrupted eight hours. The study set inpatient clinical research suite. PSG Sleep Profiler records scored by neurologist board certified medicine,...
Objective: To examine the relationship between measures of sleep quality and cognitive performance in HIV-positive individuals stable on combination antiretroviral therapy. Design: Multimethod assessments quality, patterns, were assessed a predominantly black cohort. Methods: Sleep patterns characterized 36 subjects by polysomnogram, 2-week actigraphy monitoring, validated questionnaires. Cognitive was with battery neuropsychological tests. Results: The majority participants cognitively...
Abstract Study Objectives Opioid withdrawal is an aversive experience that often exacerbates depressive symptoms and poor sleep. The aims of the present study were to examine effects suvorexant on oscillatory sleep-electroencephalography (EEG) band power during medically managed opioid withdrawal, their association with severity symptoms. Methods Participants use disorder (N = 38: age-range:21–63, 87% male, 45% white) underwent 11-day buprenorphine taper, in which they randomly assigned (20...
This Viewpoint is based on a recent panel featured at the 2017 Winter Conference Brain Research in which psychiatric comorbidities of HIV infection were discussed. Psychiatric comorbid conditions occur high rates infected patients, complicating treatment and contributing to poor outcomes. A complex relationship between comorbidity an active area investigation, but increased awareness impact complications NeuroAIDS needed both laboratory clinic better understand treat these interrelated conditions.
Obstructive sleep apnea (OSA) is a globally recognized medical condition, associated with development of long-term adverse health consequences, including cardiovascular disease, cerebrovascular neurocognitive deficiencies, and vehicular occupational accidents. OSA can be screened effectively, because it identified well before the manifestation aforementioned poor public safety consequences. Additionally, appropriate management includes an assessment outcomes after therapeutic intervention...
To present (1) justification for earmarking sleep medicine education as an essential component of all medical school curricula and (2) various avenues to incorporate exposure into through (primarily) neuroscience neurology courses.Per consensus a team leading educators, evidence-based rationale including across 4-year curriculum is presented along with suggested content, available/vetted resources, formats delivering at points formats.Growing evidence has linked disorders (e.g.,...
To identify factors associated with medical students becoming neurologists because, despite the increasing burden of neurologic disorders, there is a growing neurologist shortage.Deidentified data from Association American Medical Colleges Matriculating Student Questionnaire (MSQ) and Graduation (GQ) were obtained for graduation years 2013 to 2014 through 2016 2017. Logistic regression was used assess demographic characteristics responses training career-related questions in association...
Context Bedside clinical teaching is the backbone of clerkship education. Data-driven methods for supplementing bedside encounters with standardized content from vetted resources are needed.Objective To compare a flipped-classroom versus an interactive online-only instruction improving knowledge, skills, self-directed learning (SDL) behaviors, and satisfaction in medical school clerkship.Methods An IRB-approved prospective study employing peer-reviewed reasoning curriculum neurology was...
Poor sleep has adverse affects on heath, yet few studies have addressed the goal of improving among hospitalized patients. We evaluated effectiveness a sleep-promoting intervention quality and quantity inpatients.This study was conducted neurological ward in large, tertiary care hospital. Sleep quality, quantity, disruptors were assessed using questionnaires completed by patients during their hospital stay Press Ganey surveys retrospectively. Room noise also measured meters. Data from each 4...