- Noise Effects and Management
- Climate Change and Health Impacts
- Dental Implant Techniques and Outcomes
- Osteoarthritis Treatment and Mechanisms
- Cardiovascular Effects of Exercise
- Dental materials and restorations
- Periodontal Regeneration and Treatments
- Phonocardiography and Auscultation Techniques
- Air Quality and Health Impacts
- Mesenchymal stem cell research
- Oral and gingival health research
- Oral and Maxillofacial Pathology
- Anatomy and Medical Technology
- Dental Erosion and Treatment
- Tumors and Oncological Cases
- Thermoregulation and physiological responses
- Dental Health and Care Utilization
- Aging, Health, and Disability
- Biomedical and Engineering Education
- Geography and Environmental Studies
- Medical Malpractice and Liability Issues
- Adrenal and Paraganglionic Tumors
- Connexins and lens biology
- Pituitary Gland Disorders and Treatments
- Oral microbiology and periodontitis research
Hospital do Espírito Santo
2025
Center for Interdisciplinary Studies
2022
Hospital de Santa Maria
2013-2021
Escola Superior de Saúde Egas Moniz
2012-2021
Centro Hospitalar Lisboa Norte
2017-2021
Instituto Português Da Qualidade
2021
To test primary stability of delayed implants placed in post-extraction ridges preserved with autogenous mineralized dentin matrix (MDM) versus xenograft granules. Clinical, histological and pain experience outcomes were further assessed.From March 2018 to July 2020, patients requiring ridge preservation preparation for implant placement sites included. Participants randomly allocated either the or control group (xenograft granules) prior preservation. Visual analogue scale analgesic...
The crosstalk between tumour cells and microenvironment components in pituitary neuroendocrine tumours (PitNETs), including chemokines, may impact behaviour clinical outcomes. CCL2 was previously identified as a key chemokine PitNETs, but its role remains unknown. We aimed to study the of defining phenotype outcomes regulating macrophage chemotaxis, epithelial-to-mesenchymal transition (EMT) angiogenesis. studied E-cadherin expression, macrophages (CD68 CD163) vessels (CD31) samples from 86...
Low frequency noise (LFN) characterized by large pressure amplitude (≥ 90 dB SPL) and low bands (≤ 500 Hz) can lead to structural ultrastructural modifi cations in the extracellular matrix of several tissues, with an abnormal proliferation collagen development fi brosis. It is not known whether LFN induces similar alterations ventricular myocardium rats.Objective The aim this study was evaluate measure myocardial brosis induced LFN.Methods Two groups rats were considered: group A 26...
A 53-year-old female appeared with pain in the right mandible ramus, for past 9 months, after tooth extraction. Clinical and radiological examination using conventional advanced computerized tomography diagnostic imaging led to a provisional diagnosis of multiple complex odontomas. Complete conservative excision lesion was performed. The clinical confirmed histopathologically. Postoperative period uneventful no evidence recurrence. According an extensive literature review, this report...
Background: Conventional acrylic resin is prone to microbial colonization and may cause inflammatory allergic response. Aims: This study aims research the initial adhesion in situ tissue response an used prosthodontics. Materials Methods: Disks of a commercial were prepared included on surface individual intraoral splints fabricated for 50 participants. The 4 h, under clinical conditions. Beforehand, each participant was swabbed provide control microbiological comparison. A cytological...
Morphological changes induced by industrial noise (IN) have been experimentally observed in several organs. Histological observations of the coronary arteries showed prominent perivascular tissue and fibrosis among IN-exposed rats. The effects on small are unknown. To evaluate histomorphometric IN rat heart arteries. Twenty Wistar rats exposed to during a maximum period seven months 20 age-matched controls were studied. Hearts transversely sectioned from ventricular apex atria...
Novel bioengineering strategies for the ex vivo fabrication of native-like tissue-engineered cartilage are crucial translation these approaches to clinically manage highly prevalent and debilitating joint diseases. Bioreactors that provide different biophysical stimuli have been used in tissue engineering aimed at enhancing quality generated. However, such systems often complex, expensive, not very versatile. In current study, a novel, cost-effective, customizable perfusion bioreactor...
The lack of effective and long-term treatments for articular cartilage defects has increased the interest innovative tissue engineering strategies. Such approaches, combining cells, biomaterial matrices external biochemical/physical cues, hold promise generating fully functional tissue. Herein, this study aims at exploring use major glycosaminoglycans (GAGs), chondroitin sulfate (CS) hyaluronic acid (HA), as biochemical cues to promote chondrogenic differentiation human bone marrow-...
Tooth wear is a complex multifactorial process that involves the loss of hard dental tissue.Parafunctional habits have been mentioned as self-destructive caused by stress, which results in hyperactivity masticatory muscles.Stress manifests itself through teeth grinding, leading to progressive wear.The effects continuous exposure industrial noise, "stressor" agent, cannot be ignored and its on must evaluated.Aims: The aim this study was ascertain noise over time, identifying quantifying crown...
Abstract Recent focus has been given on the effects of high-intensity infrasound (HII) exposure, and whether it induces changes in pancreatic morphology glucose metabolism is still unknown. As such, we have studied impact HII exposure tolerance, insulin sensitivity, islet morphology, muscle GLUT4 plasma corticosterone levels. Normal intolerant wild-type Wistar rats were randomly divided two groups: one group not exposed to other continuously HII. Animals sacrificed at three timepoints (1, 6...
Morphological changes induced by industrial noise (IN) and low-frequency have been experimentally observed in several tissues organs [1–7]. Previous histological observations of the coronary artery vessels showed prominent perivascular tissue fibrotic development among IN-exposed rats [1]. The effects on small arteries rat heart are currently unknown, namely to what extent arterial wall thickening periarterial fibrosis can be IN. A preliminary evaluation IN is aim this morphometric study....
Introducao: O diagnostico pulmonar com recurso a tomografia computorizada e, nos dias de hoje, recorrente. Na tentativa promover detecao alteracoes patologicas tem sido desenvolvidos sistemas ajuda ao (CAD). presente trabalho visa identificar utilidade clinica do software CAD na nodulos pulmonares por TC, atraves uma revisao sistematica da literatura. Metodologia: Os autores efetuaram selecao estudos tendo base metodologia PRISMA onde foram incluidos todos os artigos que referenciavam...
Abstract Background Noise is an important environmental risk factor. Industrial environments are rich in high-intensity infrasound (hi-IFS), which we have found to induce myocardial and coronary perivascular fibrosis rats. Recently, a significant association between noise exposure the incidence of atrial fibrillation (AF) was large cohort studies but pathophysiology unclear. Atrial remains cornerstone pathology AF. Purpose: We hypothesized that rats exposed hi-IFS develop remodeling...
The anterior pituitary gland regulates growth, metabolism, and reproductionby secreting hormones. Folliculo-stellate cells (FSC) are non-endocrinecells located among hormone-producing in the pituitaryglands, but little is known about exact roles of those cells. Although,with their net organization, they seem to have an important role thehormonal regulation maintenance. In this work, first ever made area, 33 pituitaries three groupsof mice (18 wild type [WT], 11 genetically obese [OB] 4 under...