A5043405770- Intraoperative Neuromonitoring and Anesthetic Effects
- Meningioma and schwannoma management
- Neuroscience and Neuropharmacology Research
- Spinal Dysraphism and Malformations
- Spinal Fractures and Fixation Techniques
- Muscle activation and electromyography studies
- Motor Control and Adaptation
- EEG and Brain-Computer Interfaces
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Spinal Cord Injury Research
- Neuroscience and Neural Engineering
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Tactile and Sensory Interactions
- Electromagnetic Fields and Biological Effects
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Pituitary Gland Disorders and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Epilepsy research and treatment
- Memory and Neural Mechanisms
Christian Medical College
2011-2023
Christian Medical College & Hospital
2013-2023
Dr. Reddy's Laboratories (United States)
2021
Institute of Medical Sciences
2020
Bhabha Atomic Research Centre
2019
Government Medical College
2013
Kidwai Memorial Institute of Oncology
2007
New York University
2002
Pavlov Institute of Physiology of the Russian Academy of Sciences
1993
Hand manipulation neurons in areas 5 and 7b/anterior intraparietal area (AIP) of posterior parietal cortex were analyzed three macaque monkeys during a trained prehension task. Digital video recordings hand kinematics synchronized to neuronal spike trains used correlate firing rates 128 with actions as the animals grasped lifted rectangular round objects. We distinguished seven task stages: approach, contact, grasp, lift, hold, lower, relax. Posterior (PPC) highest object acquisition; 88%...
Variations of the external branch superior laryngeal nerve (EBSLN) are well represented in literature but with conflicting reports about types and variations. Using EMG, cricothyroid compound muscle action potential (CMAP) was recorded, to identify EBSLN classified them according clinical variation during routine thyroid operations.There is increasing awareness among patients physicians consequences injury surgeries. There at least 4 types, which described literature. The gold standard...
Introduction: Data on image-guided percutaneous procedures of the spleen are limited, particularly for infectious lesions. Aim: To evaluate complication rate ultrasound-guided splenic procedures. Materials and Methods: A retrospective observational study was conducted in a tertiary care centre Southern India. from all consecutive patients who underwent January 2008 to October 2023 were analysed. Information extracted digital radiology reports, images, inpatient records, outpatient records...
Prehension responses of 76 neurons in primary somatosensory (S-I) and motor (M-I) cortices were analyzed three macaques during performance a grasp lift task. Digital video recordings hand kinematics synchronized to neuronal spike trains compared with posterior parietal areas 5 AIP/7b (PPC) the same monkeys seven task stages: 1) approach, 2) contact, 3) grasp, 4) lift, 5) hold, 6) lower, 7) relax. S-I M-I firing patterns signaled particular actions, rather than overall goals. more diverse...
The visual outcome of 22 patients undergoing trans-sphenoidal excision pituitary macroadenomas with intraoperative flash evoked potential (VEP) monitoring (Group A), was compared a non-randomized group 14 who had undergone similar operations without VEP B). Tumour size, preoperative acuity, peripheral fields, and latencies amplitudes P1 P2 were analysed to ascertain the best predictor postoperative function. It found that in Group A significantly greater improvement field defects than those...
Neurons in posterior parietal cortex (PPC) may serve both proprioceptive and exteroceptive functions during prehension, signaling hand actions object properties. To assess these roles, we used digital video recordings to analyze responses of 83 hand-manipulation neurons area 5 as monkeys grasped lifted objects that differed shape (round rectangular), size (large small spheres), location (identical rectangular blocks placed lateral medial the shoulder). The task contained seven stages --...
This prospective study on intraoperative muscle motor evoked potentials (MMEPs) from lower-limb muscles in patients undergoing surgery for spinal cord tumors was performed to: 1) determine preoperative clinical features that could predict successful recording of MMEPs; 2) the lower limb which MMEPs be most consistently obtained; 3) assess need to monitor more than 1 per limb; and 4) effect a baseline MMEP early postoperative outcome.Of 115 consecutive tumors, 110 were included this (44...
To study the outcome of disconnective epilepsy surgery for intractable hemispheric and sub-hemispheric pediatric epilepsy.A retrospective analysis database was done in all children (age <18 years) who underwent a peri-insular hemispherotomy (PIH) or posterior quadrantectomy (PIPQ) from April 2000 to March 2011. All patients detailed pre surgical evaluation. Seizure assessed by Engel's classification cognitive skills appropriate measures intelligence that were repeated annually.There 34 all....
The filum terminale (FT) is considered a fibrous structure that extends from conus medullaris of the spinal cord to coccyx. Based on previous studies and their own experience with intraoperative electrophysiological monitoring sacral nervous system, authors postulate FT contains functional neural elements in some individuals.The was dissected 13 fresh stillborn cadavers (7 male, 6 female; mean gestational age 36 weeks 1 day). gross anatomical features were recorded, connections between nerve...
Motor impairments related to hand function are common symptoms in patients with movement disorders, such as Parkinson's disease (PD) and focal dystonia (FHD). However, dysfunction has not been quantitatively assessed a clinical tool for screening patient groups from healthy controls (HCs). The aim of our study was 1) assess PD FHD its usefulness 2) grade severity based on dysfunction.The current case-control included HCs (n = 50) known history 25) or 16). Hand by precision grip task while...
Temporal lobe epilepsy (TLE) is a common type of with hippocampus as the usual site origin. The CA3 subfield reported to have low epileptic threshold and hence initiates disorder in patients TLE. This study computationally investigates how impaired dendritic inhibition pyramidal cells vulnerable leads generation activity. A model consisting 800 cells, 200 basket (BC) Oriens-Lacunosum Moleculare (O-LM) interneurons was used. provided by O-LM be selectively some TLEs. step-wise approach taken...
Electrophysiological mapping of the sacral nervous system was used during operations on 80 patients with conus and cauda equina lesions. At surgery, under controlled muscle relaxation, neural elements (S2-4) were mapped using direct mono-polar stimulation recording compound action potentials (CMAPs) from external anal sphincter (EAS). Responses obtained in 86.25% (69/80) patients. In 33 (82.5%) out 40 preoperative deficits involving S2-4 segments, CMAPs could be elicited. Identification...
The effect of low-intensity millimeter wave electromagnetic radiation (MWR) on regeneration the rat sciatic nerve after transection and microsurgical reapproximation was examined. Rats were exposed to 54 GHz MWR at a power density 4 mW/cm2. It found that treatment femoral skin in area suture accelerated fibers. At twentieth postoperative day, MWR-treated animals had 32% increase distance compared control animals. conduction velocity showed 26% © 1996 Wiley-Liss, Inc.
Autism spectrum disorder (ASD) and temporal lobe epilepsy exhibit remarkable comorbidity, but for reasons not clearly understood. To reveal a common pathophysiological mechanism, we here describe characterize an in vitro epileptiform activity the rat hippocampus that exhibits features with vivo rodent ASD models. We discovered development of this CA1 region horizontal slices after prolonged interictal-like CA3 was provoked by incubation high potassium artificial cerebrospinal fluid. The...
Background: Despite advances in vestibular schwannoma (VS) surgery and intraoperative electrophysiological monitoring, immediate delayed facial nerve outcomes are difficult to accurately predict consistently. Objective: To determine the utility of proximal distal amplitude latency ratios predicting long-term postoperative function patients undergoing excision VS. Materials Methods: One hundred consecutive for VS with monitoring were included. Clinical, radiological, electrophysiological,...