A5013430489- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Head and Neck Anomalies
- Breast Cancer Treatment Studies
- Pituitary Gland Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- BRCA gene mutations in cancer
- Pancreatitis Pathology and Treatment
- Medical Imaging and Pathology Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Cancer Treatment and Pharmacology
- Adrenal and Paraganglionic Tumors
- Neuroblastoma Research and Treatments
- Cancer Genomics and Diagnostics
- Hormonal Regulation and Hypertension
- Voice and Speech Disorders
- Thyroid Disorders and Treatments
- Neutropenia and Cancer Infections
- Bone health and treatments
- Cancer Diagnosis and Treatment
- Bone health and osteoporosis research
- Tracheal and airway disorders
Christian Medical College & Hospital
2016-2025
Royal College of Surgeons in Ireland - Bahrain
2024
Christian Medical College
2008-2023
Endocrine Society
2015-2020
Diabetes Australia
2015
Western University
2013
Society for Vascular Surgery
2013
McGill University
2013
Development Fund
2012
Royal North Shore Hospital
2009-2011
While the molecular basis of hereditary medullary thyroid cancer (HMTC) has been well defined, little is known about pathogenesis sporadic (SMTC). In addition, microRNAs (miRNAs) have shown to be important diagnostic and prognostic markers in but not defined MTC. Our aim was study miRNA profile MTC identify biomarkers potential therapeutic targets.MiRNA microarray profiling carried out fresh frozen tissues from patients with SMTC (n = 12) HMTC 7). Differential expression three miRNAs...
Abstract Aim: To assess the positive predictive value (PPV) and inter-observer agreement of Thyroid Imaging Reporting Data System (TIRADS) as described by Kwak et al. Materials Methods: This was a prospective study wherein ultrasound performed two radiologists on patients with thyroid nodules >1 cm. The third radiologist interpreted archived images. Ultrasound features TIRADS category were compared cytology surgical histopathology. PPV calculated for all readers′ combined assessment....
Abstract Background Iron deficiency anaemia (IDA) is the most common type of in patients with Crohn’s disease (CD). Due to generally low absorption oral iron, parenteral iron therapy often preferred treatment these patients. However, resource-limited countries like India, not all can afford high costs and hospitalisations associated therapy. This study aims evaluate effectiveness CD Methods Adult presenting our centre’s Inflammatory Bowel Disease clinic from July 2021 were screened for...
Variations of the external branch superior laryngeal nerve (EBSLN) are well represented in literature but with conflicting reports about types and variations. Using EMG, cricothyroid compound muscle action potential (CMAP) was recorded, to identify EBSLN classified them according clinical variation during routine thyroid operations.There is increasing awareness among patients physicians consequences injury surgeries. There at least 4 types, which described literature. The gold standard...
Background: Although rare in non‐endemic areas, benign nodular goitre may cause acute airway obstruction and the clinical management of this condition remains a challenge. Methods: From 1996 to 2005, total 1115 patients underwent thyroid surgery at our institution these, 7 were identified have leading obstruction. They retrospectively reviewed with reference aetiology, presentation, perioperative postoperative outcome. Results: All seven elderly women history symptomatic concomitant medical...
Abdominal wall defects and hernias are commonly repaired with synthetic or biological materials. Adhesions recurrences a common problem. A study was conducted to compare Chitosan coated polypropylene mesh polypropylene-polydioxanone composite oxidized cellulose coating (Proceed™) in repair of abdominal defect Rabbit hernia model.A randomized controlled experimental done on twelve New Zealand white rabbits. ventral created each the The rabbits were divided into two groups. In one group...
To describe atypical ultrasound features of parathyroid lesions and correlate them with clinical presentation histopathology.Retrospective review 264 patients primary hyperparathyroidism who underwent imaging prior to parathyroidectomy was performed. Patients findings (n = 26) were identified; correlated histopathology.Twenty-one (80 %) adenomas, two (8 adenomas cellular atypia, three (11.5 carcinomas. Seventeen (65 showed cystic change; five (19 had >50 % change. These degeneration. Cystic...
Thyroid nodule (TN), a discrete palpable swelling of the thyroid gland, is prevalent among 8% adult population. The important concern with these nodules differentiation between benign and malignant ones. Since conventional diagnostic techniques (e.g., ultrasound) are not accurate in diagnosis, clinical surgeons adopt to excision biopsy, golden standard, which requires surgery removal gland. We propose apply Photoacoustic Spectral Response (PASR), non-invasive elasticity based technique, onto...
Abstract The increased detection of thyroid nodules in the human population has led to an increase number surgeries without improvement survival outcomes. Though choice for surgery is straightforward malignant nodules, decision far more complex those that get categorized into indeterminate (ITN) by fine needle aspiration. Therefore, there a pressing need develop tool will aid decision-making among ITN. In this context, development various molecular testing (MT) panels helped confirm or rule...
Carcinoembryonic antigen (CEA) is a tumour marker commonly associated with gastrointestinal malignancy. Patients presenting an elevated CEA will therefore often undergo extensive investigations in order to elucidate underlying malignancy that may not be clinically apparent. However the GI tract only source of elevation.We present series patients raised levels were initially investigated for cause, but after work up detected have medullary thyroid cancer.Four evaluated cause elevation. We...
We have analyzed the risk factors and impact of external beam radiotherapy (EBRT) in reducing locoregional recurrence parathyroid carcinoma (PTC).Various parameters such as clinical presentation, intraoperative findings, surgical methods, usage parafibromin were analyzed. Selected endpoints progression-free survival overall survival.Three patients had local recurrence. Two them received EBRT after first but continued to One patient was lost follow-up. Six with remain asymptomatic a 42...