Emmanuel Simon

ORCID: 0000-0001-6442-1013
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Maternal and fetal healthcare
  • Maternal and Perinatal Health Interventions
  • Assisted Reproductive Technology and Twin Pregnancy
  • Gestational Diabetes Research and Management
  • Ultrasound Imaging and Elastography
  • Prenatal Screening and Diagnostics
  • Ultrasound and Hyperthermia Applications
  • Cardiovascular Issues in Pregnancy
  • COVID-19 Impact on Reproduction
  • Paleontology and Stratigraphy of Fossils
  • Ectopic Pregnancy Diagnosis and Management
  • Fetal and Pediatric Neurological Disorders
  • Paleontology and Evolutionary Biology
  • Neonatal Respiratory Health Research
  • Pelvic and Acetabular Injuries
  • Maternal Mental Health During Pregnancy and Postpartum
  • Meta-analysis and systematic reviews
  • Global Maternal and Child Health
  • Pregnancy-related medical research
  • Reproductive Health and Contraception
  • Pregnancy and Medication Impact
  • Preterm Birth and Chorioamnionitis
  • Pelvic floor disorders treatments
  • Ultrasound in Clinical Applications

Christian Medical College & Hospital
2024-2025

CHU Dijon Bourgogne
2019-2024

Maison des Sciences de l’Homme de Dijon
2021-2024

Université de Bourgogne
2021-2024

Inserm
2013-2022

Université Bourgogne Franche-Comté
2021-2022

Centre Hospitalier Universitaire de Tours
2012-2021

Université de Tours
2010-2019

Hôpital Bretonneau
2008-2019

NVH Medicinal (France)
2019

Intrahepatic cholestasis of pregnancy (ICP) is characterised by troublesome maternal pruritus, raised serum bile acid levels and increased fetal risk. Mutations the ABCB4 gene encoding hepatobiliary phospholipid transporter have been identified in a small proportion patients with pregnancy. In recent prospective study on 693 pregnancy, cut-off level for (> or =40 micromol/l) was determined risk complications.To investigate whether common combinations polymorphic alleles (haplotypes) genes...

10.1136/gut.2006.092742 article EN Gut 2006-08-05

<h3>Importance</h3> Randomized trials have not focused on neonatal complications of glyburide for women with gestational diabetes. <h3>Objective</h3> To compare oral vs subcutaneous insulin in prevention perinatal newborns <h3>Design, Settings, and Participants</h3> The Insulin Daonil trial (INDAO), a multicenter noninferiority randomized conducted between May 2012 November 2016 (end participant follow-up) 13 tertiary care university hospitals France including 914 singleton pregnancies...

10.1001/jama.2018.4072 article EN JAMA 2018-05-01

Previous studies of fetal effects have suggested that intrahepatic cholestasis pregnancy is associated with a higher rate adverse neonatal outcomes including preterm birth, respiratory distress syndrome, meconium-stained amniotic fluid, intensive care unit admission, and stillbirth. The objective was to compare the maternal consequences in pregnancies affected by normal pregnancies. This case-control study compares (pruritus bile acid ≥ 10 μmol/L) low-risk managed between December 2006 2014...

10.1371/journal.pone.0228213 article EN cc-by PLoS ONE 2020-02-19

To determine the impact of maternal coronavirus disease 2019 (COVID-19) on prematurity, birthweight and obstetric complications.

10.1111/1471-0528.17135 article EN cc-by-nc-nd BJOG An International Journal of Obstetrics & Gynaecology 2022-03-07

BackgroundThe increased maternal cardiocerebrovascular risk after a pregnancy complicated by hypertensive disorders of pregnancy, is well documented in the literature. Recent evidence has suggested shorter timeframe for development these postnatal outcomes, which could have major clinical implications.ObjectiveThis study aimed to determine and time onset cardiovascular cerebrovascular outcomes pregnancy.Study DesignThis included 2,227,711 women, without preexisting chronic hypertension, who...

10.1016/j.ajog.2023.03.021 article EN cc-by-nc-nd American Journal of Obstetrics and Gynecology 2023-03-17

Abstract To quantify transplacental transmission of SARS-CoV-2 virus and antibody transfer in pregnant women their newborns according to the gestational age at maternal infection. A prospective observational multicenter study including with a positive RT-PCR or serology for compatible symptoms, from April December 2020, 11 French maternities. The was designed obtain systematic collection mother-infant dyad’s samples birth. viral load measured by RT-PCR. IgG IgM antibodies against spike...

10.1038/s41598-024-53580-5 article EN cc-by Scientific Reports 2024-02-11

Abstract Background Iron deficiency anaemia (IDA) is the most common type of in patients with Crohn’s disease (CD). Due to generally low absorption oral iron, parenteral iron therapy often preferred treatment these patients. However, resource-limited countries like India, not all can afford high costs and hospitalisations associated therapy. This study aims evaluate effectiveness CD Methods Adult presenting our centre’s Inflammatory Bowel Disease clinic from July 2021 were screened for...

10.1093/ecco-jcc/jjae190.1221 article EN Journal of Crohn s and Colitis 2025-01-01

In the first trimester of pregnancy, a biparietal diameter (BPD) below 5(th) percentile is simple marker that enables prenatal detection half all cases open spina bifida. We hypothesized relating BPD measurement to transverse abdominal (TAD) might be another and effective screening method. this study we assessed performance using BPD/TAD ratio during pregnancy in for bifida.A total 20,551 first-trimester ultrasound scans (11-13 weeks' gestation), performed between 2000 2013, were analyzed...

10.1002/uog.13406 article EN Ultrasound in Obstetrics and Gynecology 2014-05-10

This study aimed to establish whether there was a decrease in the rate of prematurity France after beginning lockdown (March 17, 2020) and an increase stillbirths compared with 2017 2019. We included all births from January September each year 2020 national Programme de Médicalisation des Systèmes d'Information database: 496,171 newborns women singleton pregnancies 15,441 multiple were for 2020. Concerning 2019 period, we mean 518,798 16,441 per year. Prematurity defined according World...

10.1016/j.ajog.2021.05.015 article EN other-oa American Journal of Obstetrics and Gynecology 2021-05-19

Abstract Background The potential protective effect of mediolateral episiotomy for obstetrical anal sphincter injuries (OASIs) remains controversial during operative vaginal delivery because the difficulties to take into account risk factors and clinical conditions at delivery; in addition, little is known about benefits on neonatal outcomes. objectives were investigate associations between both OASIs outcomes, using propensity scores. Methods We performed a retrospective population-based...

10.1186/s12884-022-04396-6 article EN cc-by BMC Pregnancy and Childbirth 2022-01-19

To evaluate the risk of non-lethal self-harm and mortality related to adolescent pregnancy.Nationwide population-based retrospective cohort.Data were extracted from French national health data system.We included all adolescents aged 12-18 years with an International Statistical Classification Diseases Related Health Problems, 10th Revision (ICD-10) code for pregnancy in 2013-2014.Pregnant compared age-matched non-pregnant first-time pregnant women 19-25 years.Any hospitalisation during a...

10.1111/1471-0528.17432 article EN cc-by-nc-nd BJOG An International Journal of Obstetrics & Gynaecology 2023-02-20

Objective. The purpose of this study was to assess the feasibility using a contrast agent for sonographic examination adnexal tumors and identify discriminating parameters in preoperative diagnosis malignant tumors. Methods. We conducted prospective descriptive monocenter that analyzed validated echographic criteria enhancement curve obtained by injection. Patients included were referred second opinion after discovery suspicious ovarian image. final reached surgery an anatomopathologic...

10.7863/jum.2010.29.7.1041 article EN Journal of Ultrasound in Medicine 2010-07-01

To analyze the anatomical relationship between pubic symphysis and ischial spines to determine reliable landmarks for assessment of fetal head descent by intrapartum translabial ultrasound (ITU).All computed tomography (CT) scans performed breech presentation twin delivery 2006 2014 in a tertiary university hospital were obtained measurement analysis two operators. The symphysis-left spine angle (SIA) distance (SID) measured on three-dimensional reconstructions from CT volume dataset. We...

10.1002/uog.15842 article EN Ultrasound in Obstetrics and Gynecology 2015-12-18

Background Placental elasticity may be modified in women with placental insufficiency. Shear wave elastography (SWE) can measure this, using acoustic radiation force, but the safety of its use pregnant has not yet been demonstrated. Transient (TE) is a safer alternative, applied to placenta. Moreover, dispersion shear speed (SWS) as function frequency received relatively little study for tissue, although it might improve accuracy biomechanical assessment. Objective To explore feasibility and...

10.1371/journal.pone.0194309 article EN cc-by PLoS ONE 2018-04-05
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