A5065143968- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- Pelvic floor disorders treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy-related medical research
- Gestational Diabetes Research and Management
- Neonatal Respiratory Health Research
- Congenital Anomalies and Fetal Surgery
- Cardiovascular Issues in Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Anorectal Disease Treatments and Outcomes
- Prenatal Screening and Diagnostics
- Pelvic and Acetabular Injuries
- Uterine Myomas and Treatments
- Birth, Development, and Health
- Preterm Birth and Chorioamnionitis
- Urological Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Neonatal and fetal brain pathology
- Fetal and Pediatric Neurological Disorders
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Congenital Diaphragmatic Hernia Studies
- Congenital Heart Disease Studies
Université de Rouen Normandie
2016-2025
Hôpital Charles-Nicolle
2010-2025
Centre Hospitalier Universitaire de Rouen
2014-2024
Normandie Université
2019-2024
Inserm
2013-2023
Université de Bordeaux
2023
Community Link
2020-2023
Santé Publique France
2023
French Clinical Research Infrastructure Network
2021
Assistance Publique – Hôpitaux de Paris
2014-2018
Prophylactic administration of tranexamic acid has been associated with reduced postpartum blood loss after cesarean delivery in several small trials, but evidence its benefit this clinical context remains inconclusive.
In Brief OBJECTIVES: To estimate what factors are associated with a failed pelvic arterial embolization for postpartum hemorrhage and to attempt efficacy of in rare conditions. METHODS: This was retrospective cohort study including all consecutive women who underwent trial between 1994 2007 at tertiary care center. Pelvic failure defined as the requirement subsequent surgical procedure control hemorrhage. RESULTS: attempted 0.3% deliveries by same radiologist 87% cases. Failures occurred 11...
OBJECTIVE: To evaluate the association between planned mode of delivery and neonatal mortality morbidity in an unselected population women with twin pregnancies. METHODS: The JUmeaux MODe d'Accouchement (JUMODA) study was a national prospective population-based cohort study. All pregnancies their neonates born at or after 32 weeks gestation cephalic first were recruited 176 maternity units France from February 2014 to March 2015. primary outcome composite intrapartum morbidity. Comparisons...
To evaluate the fertility and pregnancy outcomes following uterine devascularization for postpartum haemorrhage (PPH).All patients who required devascularization, i.e. bilateral artery ligation (Group A), either utero-ovarian ligament B) or suspensory of ovary C) in cases persistent haemorrhage, PPH with no concomitant procedures from December 1997 to March 2004 were included. Data retrieved medical files telephone interviews.Data available 32 40 (80%) included study. All but 4 had a return...
To determine and compare the fertility pregnancy outcomes following embolisation with or without uterine-sparing surgery for postpartum haemorrhage, to attempt identify specific risk factors associated an increased likelihood of intrauterine synechia.Retrospective study.University-affiliated tertiary referral centre.All consecutive women who had (vessel ligation and/or uterine compression) haemorrhage between 1994 2007 were included.Data retrieved from medical files telephone...
<h3>Importance</h3> Randomized trials have not focused on neonatal complications of glyburide for women with gestational diabetes. <h3>Objective</h3> To compare oral vs subcutaneous insulin in prevention perinatal newborns <h3>Design, Settings, and Participants</h3> The Insulin Daonil trial (INDAO), a multicenter noninferiority randomized conducted between May 2012 November 2016 (end participant follow-up) 13 tertiary care university hospitals France including 914 singleton pregnancies...
To assess whether outpatient cervical ripening at 41 0/7 weeks of gestation with the nitric oxide donor isosorbide mononitrate reduces cesarean delivery rates in nulliparous women an unfavorable cervix.We recruited pregnant a Bishop score less than 6 randomized, multicenter, double-blind, placebo-controlled trial. Women received 40 mg vaginal or placebo 0/7, 2/7, and 4/7 gestation. They returned home between visits. At 5/7 gestation, for who had not yet given birth, labor was induced...
Spinal muscular atrophy (SMA) is caused by homozygous inactivation of the SMN1 gene. The SMN2 copy number modulates severity SMA. 0SMN1/1SMN2 genotype, most severe genotype compatible with life, expected to be associated form disease, called type 0 SMA, defined prenatal onset.The aim study was review clinical features and manifestations in this rare SMA subtype.SMA patients were retrospectively collected using UMD-SMN1 France database.Data from 16 reviewed. These displayed At birth, a vast...
To estimate the effectiveness and safety of B-Lynch suture for severe persistent postpartum hemorrhage (PPH) following vessel ligation before considering hysterectomy its impact on menstruation uterine cavity.Cohort study.University-affiliated tertiary referral center. Population. Fifteen consecutive women who underwent PPH despite ligation.Data were retrieved from medical files telephone interviews.Hysterectomy, infection, hysteroscopy, future menstruations.In 13 15 cases (86.7%), occurred...
Obesity has significant implications for the health of pregnant women. However, few studies have quantified its association with maternal mortality or examined relevant underlying causes and role care, although this remains most severe outcome. Our objectives were to quantify risk death by prepregnancy body mass index determine whether obesity affected quality care women who died.This is a national population-based case-control study in France. Cases 364 deaths from 2007-2012 National...
To compare the Bishop score, ultrasound cervical parameters and fetal fibronectin assessment for predicting failed labor induction when cervix is unfavorable.A prospective observational study was performed in 106 consecutive pregnant women with a score < or =5 undergoing induction. Assessment of measurement length, wedging lip areas were performed. The relationship between these failure determined.Failure defined as to reach dilatation > cm, it occurred 16 patients (15.1%). Induction...
Abstract Transient myasthenia gravis was observed in an infant whose mother had no signs of neuro‐muscular disease. The case presented with severe polyhydramnios at 31 weeks. Sonographic and invasive work‐up showed only absence fetal swallowing. At birth, the muscle weakness respiratory distress. He high titres anti‐acetylcholine receptor (anti‐AChR) antibodies maternal origin. Anti‐AChR were also found stored samples serum amniotic fluid. To our knowledge, this is first neonatal for which...
To compare the incidence of antenatal and intrapartum complications neonatal outcomes among grand multiparas with age-matched multiparas.Six hundred twenty-one (para more than 4) women were prospectively compared 621 multiparous 2-4) controls.Grand multiparity was associated low socioeconomic status education (odds ratio [OR]6.4; 95% confidence interval [CI] 4.5, 9.0), poorer prenatal care (OR 3.1; CI 1.5, 6.1), smoking 2.2; 3.2), alcohol consumption 9.0; 2.1, 39.3). Grand had a higher body...
In Brief BACKGROUND: Treatment with ursodeoxycholic acid in intrahepatic cholestasis of pregnancy reduces concentration transaminases and bile acids maternal serum, is thought to reduce fetal death. We report a case death patient who had responded well acid, demonstrated by low level. CASE: A young nulliparous woman presented at 28 weeks gestation. Transaminases decreased after administration. The was discharged from the hospital until delivery received biochemical markers conventional...
Abstract Objective This study aimed to explore the perceptions of French residents and academic teachers regarding residents' autonomy during training their preparedness perform standard gynecological procedures. Methods A national survey obstetrics gynecology was conducted using an online questionnaire distributed in 2023, which gathered opinions on level granted operating room for performing procedures upon graduation. The also examined impact factors that improve surgical autonomy....