- Ultrasound and Hyperthermia Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Multiple Myeloma Research and Treatments
- MRI in cancer diagnosis
- Cancer Treatment and Pharmacology
- Heart Rate Variability and Autonomic Control
- Ultrasound Imaging and Elastography
- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Hematological disorders and diagnostics
- Neonatal Health and Biochemistry
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Radiation Dose and Imaging
- Metabolism and Genetic Disorders
- Blood disorders and treatments
- Advanced X-ray and CT Imaging
- Pleural and Pulmonary Diseases
- Hepatocellular Carcinoma Treatment and Prognosis
- Bone health and treatments
- Cardiovascular Health and Disease Prevention
- Complement system in diseases
- Pericarditis and Cardiac Tamponade
Clinical Investigation Center Plurithematic Tours
2016-2024
Université de Tours
2017-2024
Inserm
2016-2024
Centre Hospitalier Universitaire de Tours
2013-2023
Adaptation Biologique et Vieillissement
2018-2023
Thion Medical (France)
2023
Centre d'Investigation Clinique - Innovation Technologique
2013
Institut de Chimie de Nice
1998
Abstract Purpose To evaluate changes in tumor vascularization parameters based on contrast-enhanced ultrasound (CEUS) quantification criteria of at least one visible liver metastasis as an early predictor non-response to chemotherapy, including bevacizumab for colorectal cancer (CRC) metastases. Materials and Methods This multicenter prospective study included patients who received first-line bevacizumab-based chemotherapy. Tumor enhancement measured using CEUS within relation the...
Contrast-enhanced ultrasound (CEUS) is a non-invasive imaging technique extensively used for blood perfusion of various organs. This modality based on the acoustic detection gas-filled microbubble contrast agents as intravascular flow tracers. Recent efforts aim at quantifying parameters related to enhancement in vascular compartment using time-intensity curve (TIC), and these latter indicators several pathological conditions. However, this quantification mainly hampered by two reasons:...
Abstract Background Nonalcoholic fatty liver disease (NAFLD) refers to a large spectrum of disorders and is the most common cause metabolic disease. The current gold standard for diagnosing NAFLD biopsy, which can lead severe complications. Purpose Among noninvasive diagnostic options, we chose use FibroScan developed an algorithm applying Voigt rheological model assess viscoelastic properties evaluate its performance diagnosis steatosis. Methods Twenty‐two healthy volunteers 20 patients...
High-frequency transient elastography (HF-TE) is a noninvasive technique for assessing shear-wave speed and finally elasticity in thin tissue such as the skin. It has never been validated monitoring fibrotic skin diseases. The purpose was to evaluate potential of HF-TE assess fibrosis patients with chronic venous disorders (CVD). This clinical study enrolled 48 at various stages CVD paired healthy volunteers. Subjects underwent examination an evaluation Rodnan's score. We studied dermis...
Introduction The aim of this study was to evaluate how chest computed tomography (CT) can predict pejorative evolution in COVID-19 patients. Material and methods Data on 349 consecutive patients who underwent a CT either for severe suspected pneumonia or clinical aggravation with were retrospectively analysed. In total, 109 had laboratory-confirmed infection by positive reverse-transcription polymerase chain reaction (RT-PCR) included. main outcomes death the need invasive endotracheal...
Chest radiography is one of the most frequent x-ray examinations performed on children. Reducing delivered dose always a major task. The objective our study was to determine minimum be while maintaining image quality chest radiographs, using reduction simulation software.We included 60 children who had in 5 groups established according diagnostic reference levels equitably represented by weight ranges. software simulated for each radiograph 6 additional photonic noise images corresponding...