- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Neonatal and fetal brain pathology
- Functional Brain Connectivity Studies
- Cerebrovascular and Carotid Artery Diseases
- Lanthanide and Transition Metal Complexes
- Neurological disorders and treatments
- Metabolism and Genetic Disorders
- Metabolomics and Mass Spectrometry Studies
- Medical Imaging Techniques and Applications
- Optical Imaging and Spectroscopy Techniques
- Psychosomatic Disorders and Their Treatments
- Acute Ischemic Stroke Management
- Neurofibromatosis and Schwannoma Cases
- Traumatic Brain Injury and Neurovascular Disturbances
- MRI in cancer diagnosis
- Molecular Sensors and Ion Detection
- Radioactive element chemistry and processing
- Medical Image Segmentation Techniques
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Intracranial Aneurysms: Treatment and Complications
- Posttraumatic Stress Disorder Research
- Nanocluster Synthesis and Applications
- Birth, Development, and Health
- Cerebrospinal fluid and hydrocephalus
Inserm
2014-2025
Université de Tours
2014-2025
Centre Hospitalier Universitaire de Tours
2010-2024
Institut de Recherche en Informatique et Systèmes Aléatoires
2023
CIC Rennes
2023
Centre Hospitalier Universitaire de Rennes
2023
Cognition Behaviour Technology
2023
Centre Hospitalier Guillaume Régnier
2023
Clinical Investigation Center Plurithematic Tours
1999-2023
Université de Rennes
2023
The ERETIC method (Electronic REference To access In vivo Concentrations) provides a reference signal, synthesized by an electronic device, which can be used for the determination of absolute concentrations. results presented here demonstrate accuracy and precision in case 1H high resolution NMR. Five tubes were filled with D2O solutions trimethylamine hydrochloride (TMA) 3.84 mM sodium lactate at concentrations ranging from 5.25 to 54.11 mM. Results obtained compared those using TMA as...
A new method for absolute quantitation of MRS spectra is presented. This not based on a reference peak, derived from real NMR signal, but rather synthesized produced by an electronic device, transmitted broad-band antenna to avoid quality factor variations. signal therefore received at the same time as sample signal. The line stable in (maximum variation lower than 2%) and allows precise accurate measurement concentrations (mean error 3%) vitro vivo.
<h3>Background:</h3> Posttraumatic stress disorder (PTSD) is associated with medial frontal and amygdala functional alterations during the processing of traumatic material frontoparietal dysfunctions working memory tasks. This magnetic resonance imaging (fMRI) study investigated effects trauma-related words on in patients PTSD. <h3>Methods:</h3> We obtained fMRI scans a 3-back task an identity both neutral women PTSD who had been sexually abused healthy, nonexposed pair-matched controls....
Traditional teaching methods struggle to convey three-dimensional concepts effectively. While 3D virtual models and reality platforms offer a promising approach anatomy, their cost specialized equipment pose limitations, especially in disadvantaged areas. A simpler alternative is use displayed on regular screens, but they lack immersion, realism, stereoscopic vision. To address these challenges, we developed an affordable method utilizing smartphone-based 360° photogrammetry, camera...
A bioinspired probe based on a zinc finger peptide functionalized by lanthanide(iii)-DOTA monoamide complex turns out to be active for both luminescence and MRI detection of Zn2+, depending the lanthanide cation. mechanism MRI-based is proposed.
We propose quantitative assessment of zinc by combining nuclear and MR imaging. use a cocktail Gd3+-complex providing Zn2+-dependent MRI response its 165Er3+ analogue allowing for concentration assessment. 165Er is readily obtained in cyclotron purified, which indispensable successful quantification metal ions.
Thrombus composition has the potential to affect acute ischemic stroke (AIS) treatment.To evaluate in an vitro test correlation of clot composition, especially erythrocytes (red blood cells (RBCs)), with variation signal intensity ratio (SIR) obtained MRI sequences used for AIS, and qualification susceptibility vessel sign effect using analogs.Nine ovine clots were fixed a gelatin-manganese solution studied by (T2GE, T2-weighted gradient echo; SWI, susceptibility-weighted imaging; FLAIR,...
The aim of this study was to evaluate in healthy human brain the distribution, uptake, and kinetics [18F]LBT-999, a PET ligand targeting dopamine transporter, assess its ability explore dopaminergic innervation, using shorter protocol, more convenient for patients than currently with [123I]ioflupane.After intravenous injection 8 subjects (53-80y) underwent dynamic PET-scan. Venous samples were concomitantly obtained metabolites analysis. Time activity curves (TACs) generated several ROIs...
Survivors of sexual assault are vulnerable to long-term negative psychological and physical health outcomes, but few studies have investigated changes in cognition, emotional processing brain function the early stages after assault. We used a multimodal approach identify cognitive correlates associated with women.Twenty-seven female survivors were included within 4 weeks traumatic event, they compared 20 age-matched controls. Participants underwent functional MRI while performing...