A5082130145- Rabies epidemiology and control
- Yersinia bacterium, plague, ectoparasites research
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Poxvirus research and outbreaks
- Bat Biology and Ecology Studies
- Vector-borne infectious diseases
- Venomous Animal Envenomation and Studies
- Wildlife Ecology and Conservation
- Toxin Mechanisms and Immunotoxins
- Bacillus and Francisella bacterial research
- Microbial infections and disease research
- Insect symbiosis and bacterial influences
- Streptococcal Infections and Treatments
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- Zoonotic diseases and public health
- Trypanosoma species research and implications
Universidade Brasil
2024
Universidade de São Paulo
2016-2024
Rickettsia rickettsii is vectored by ticks, and some vertebrate hosts can be sources of infection to ticks during bacteremic periods. In Brazil, the main vector for R. tick Amblyomma sculptum, a member A. cajennense complex. Horses, in turn, are one major sculptum. this study, horses experimentally infected with were assessed clinical changes their capability transmit sculptum ticks. Four through either intraperitoneal injection or infestation rickettsii-infected Simultaneously, animals...
Lyssavirus rabies (RABV) is an RNA virus and, therefore, subject to mutations due low polymerase replication fidelity, forming a population structure known as viral quasispecies, which the core of viruses' adaptive strategy. Under new microenvironmental conditions, fittest populations are selected, and study this process on molecular level can help determine signatures related virulence. Our aim was survey gene nucleoprotein glycoprotein genes that might be involved in virulence modulation...
Rabies is an emerging zoonosis of global significance in the context one health. With advent mass vaccination campaigns for dogs and cats Brazil, urban rabies maintained by these animals has been controlled, but not eradicated. In contrast, wildlife-maintained virus always a challenge. Ceará, primate Callithrix jacchus significant transmitter. The aim this study was to investigate occurrence frequency wildlife area municipalities Northwest Ceará describe species infected animals. Active...
This publication reports on a rabid dog in São Paulo city, Brazil, with the AgV3 variant of rabies virus related to vampire and fruit bats, which is significant importance surveillance region where typical canine AgV2 has been eradicated.
Samples of brain cortex 12 free-range healthy wild boars from Southern Brazil were tested for RABV by dFAT and qPCR, all negative. The negative results in seropositive may be associated with exposure non-viable virus particles, proteins bat saliva or consumption contaminated carcasses.
ABSTRACT: Rabies is a fatal viral disease that affects animals and humans widespread among national ecological systems. We describe the anatomopathological immunohistochemical findings of case rabies in jaguarundi (Herpailurus yagouaroundi) found rural peri-domestic area after showing aggression attacking two animals. Histopathology brain tissue showed lymphoplasmacytic meningoencephalitis associated with intracytoplasmic eosinophilic inclusion bodies neurons, gliosis neuronophagia. The...
Abstract Of the 181 Brazilian bat species (Mammalia: Chiroptera), 46,7% occur in urban areas. However, little is known about influence of these environments on species’ ecology, and few studies community structure Brazil have been published to date. The urbanization process, however, potentially lead critical ecological changes communities’ intra interspecific pathogenic transmissions dynamics. Conversely, papers detected pathogens bats. present work aimed perform captures a...
Abstract Despite its 100% lethality and approximately 59,000 human deaths a year, rabies is still in want of an effective treatment. A host trials has been described aiming at impairing the life cycle Lyssavirus (RABV), chief worldwide lyssavirus causing rabies, but with limited success. In this study, mice intranasally inoculated CVS strain RABV were serially treated 50µg/day Poly ICLC Hiltonol® jn MEM showed significantly higher survival time disease incubation period as compared to...
Abstract Rabies is a zoonotic neurological disease with 100% lethality. Some of the rare human patients who survived after multiple drug treatment have inherited severe sequelae. The objective this study was to investigate action transfection antibodies against rabies in central nervous system mice as target therapy for rabies. Author summary present showed that 48 h RABV inoculation, injected by intracerebral route anti-RABV F(ab’) 2 complexed Bioporter® Protein Delivery Reagent (Genlantis)...