Milena Simeoni
A5052459099- Cancer Risks and Factors
- Nutritional Studies and Diet
- Nutrition, Genetics, and Disease
- Metabolism, Diabetes, and Cancer
- Cancer, Lipids, and Metabolism
- Colorectal Cancer Screening and Detection
Ospedale San Pietro Fatebenefratelli
2014-2023
The DIANA (Diet and Androgens)-5 study is a multi-institutional randomized controlled trial of the effectiveness diet based on Mediterranean macrobiotic recipes principles, associated with moderate physical activity, in reducing additional breast cancer events women early stage invasive at high risk recurrence because metabolic or endocrine milieu. intervention expected to reduce serum insulin sex hormones, which were prognosis previous studies.Between 2008 2010, randomly assigned 1208...
Metabolic syndrome (MetS), conventionally defined by the presence of at least three out five dismetabolic traits (abdominal obesity, hypertension, low plasma HDL-cholesterol and high glucose triglycerides), has been associated with both breast cancer (BC) incidence prognosis. We investigated association between prevalence MetS a score adherence to World Cancer Research Fund (WCRF) American Institute for (AICR) recommendations prevention in cross-sectional study BC patients. The DIet...
The Diet and Androgen-5 (DIANA-5) trial aimed at testing whether a dietary change based on the Mediterranean diet macrobiotic principles can reduce incidence of breast cancer (BC)-related events. We analyzed adherence to DIANA-5 recommendations by randomization group after 1 year intervention. evaluated association between changes in body weight metabolic syndrome (MS) parameters. BC women aged 35-70 years were eligible. After baseline examinations, randomized into an intervention (IG) or...
Abstract Purpose: The DIANA-5 randomized controlled trial assessed the effectiveness of a diet based on Mediterranean and macrobiotic traditions (macro-Mediterranean diet) in reducing breast cancer recurrence. Patients Methods: study involved 1,542 patients with at high risk recurrence because estrogen receptor–negative cancer, or metabolic syndrome, plasma levels insulin testosterone. Women were randomly assigned to an active dietary intervention (IG) control group (CG). Both groups...
<p>Supplementary Figure 1; Supplementary 2; Table 1 ; 3; 2</p>
<p>Representativeness of Study Participants</p>
<p>Representativeness of Study Participants</p>
<div>AbstractPurpose:<p>The DIANA-5 randomized controlled trial assessed the effectiveness of a diet based on Mediterranean and macrobiotic traditions (macro-Mediterranean diet) in reducing breast cancer recurrence.</p>Patients Methods:<p>The study involved 1,542 patients with at high risk recurrence because estrogen receptor–negative cancer, or metabolic syndrome, plasma levels insulin testosterone. Women were randomly assigned to an active dietary intervention (IG)...
<div>AbstractPurpose:<p>The DIANA-5 randomized controlled trial assessed the effectiveness of a diet based on Mediterranean and macrobiotic traditions (macro-Mediterranean diet) in reducing breast cancer recurrence.</p>Patients Methods:<p>The study involved 1,542 patients with at high risk recurrence because estrogen receptor–negative cancer, or metabolic syndrome, plasma levels insulin testosterone. Women were randomly assigned to an active dietary intervention (IG)...
<p>Supplementary Figure 1; Supplementary 2; Table 1 ; 3; 2</p>
Background. Metabolic syndrome (MetS), and high levels of glucose, insulin testosterone are associated with a worse breast cancer (BC) prognosis. Mediterranean diet protects from MetS its metabolic/hormonal imbalance. The DIANA-5 randomized controlled trial aimed to assess the effectiveness based on macrobiotic traditions (macro-Mediterranean® diet) in reducing BC recurrences.Methods: DIANA-5, run 11 Italian clinical centres, involved 1542 patients at risk recurrences because ER-negative...