Н. Н. Никулина

ORCID: 0000-0001-8593-3173
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About
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Research Areas
  • Healthcare Systems and Public Health
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Atrial Fibrillation Management and Outcomes
  • Human Health and Disease
  • Cardiac electrophysiology and arrhythmias
  • Venous Thromboembolism Diagnosis and Management
  • Blood Pressure and Hypertension Studies
  • Cardiac Health and Mental Health
  • Cardiovascular Health and Risk Factors
  • Hormonal Regulation and Hypertension
  • Poisoning and overdose treatments
  • Cardiovascular Syncope and Autonomic Disorders
  • Dialysis and Renal Disease Management
  • Economic and Technological Systems Analysis
  • Heart rate and cardiovascular health
  • Engineering and Environmental Studies
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Function and Risk Factors
  • Central Venous Catheters and Hemodialysis
  • Cardiovascular Disease and Adiposity
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Statistical and Computational Modeling
  • Pathogenesis and Treatment of Hiccups
  • Chronic Obstructive Pulmonary Disease (COPD) Research

Ryazan State Medical University named after Academician I.P. Pavlov
2011-2025

Engineering (Italy)
2017

Riga Stradiņš University
2011

Research Institute of Complex Problems of Cardiovascular Disease Russian Academy of Medical Sciences
2011

Ryazan State University
2006

Coronary heart disease (CHD) is one of the most common cardiovascular diseases and cause death in Russia. Primary diagnostics CHD involves assessing pre-test probability CHD. Thereafter, myocardial ischemia should be verified by visualization technique: stress echocardiography or single-photon emission computed tomography myocardium. Myocardial revascularization improves prognosis patients with stable who have three-vessel coronary significant stenosis left main artery. Outpatient monitoring...

10.26442/00403660.2025.01.203125 article EN cc-by-nc Terapevticheskii arkhiv 2025-02-20

The article discusses the statement of diagnosis hypertension (HTN) with severe left ventricular systolic dysfunction and resulting decrease in blood pressure (BP) to target levels or hypotension ("decapitated hypertension"). current Russian guidelines on HTN adults heart failure (HF) do not consider this situation. used classifications by its degree untreated patients achievement BP level antihypertensive therapy cannot correctly reflect situation case, since as such no longer exists, but a...

10.15829/1560-4071-2025-6234 article EN cc-by Russian Journal of Cardiology 2025-03-14

Aim. To comparatively analyze the registered mortality rates from coronary heart disease (CHD) as a whole, well myocardial infarction (MI) and other acute forms of CHD during 15-year period in Russian Federation (RF, 2000—2014) United States America (USA, 1999-2013). Materials methods. Primary data were obtained database RF State Statistics Service, World Health Organization Mortality Database, Human then converted into standardized are presented three age groups (30+, 30-49, 50+ years old)...

10.17116/terarkh201789953-59 article EN Terapevticheskii arkhiv 2017-09-15

Pulmonary embolism (PE) is the third most common cardiovascular disease (estimated incidence in Europe and United States at least 250000-300000 per year), as well one of main causes death. At same time, over past two decades, there has been a steady increase PE with relatively stable prevalence deep vein thrombosis. Obtaining objective epidemiological statistical information on difficult due to difficulties diagnostics (non-specificity clinical symptoms, late seeking medical attention,...

10.15829/1560-4071-2019-6-103-108 article EN cc-by Russian Journal of Cardiology 2019-07-08

Aim.To estimate risk factors and comorbidity structure, cardiovascular diseases outcomes, evaluate their diagnostics treatment quality in real outpatient practice using a register of patients with arterial hypertension (HT), ischemic heart disease (IHD), chronic failure (CHF) atrial fibrillation (AF) the Ryazan Region -the territorial subject Russian Federation high mortality rate.Material methods.The total 1000 HT, IHD, CHF, AF patients, applied for general practitioners or cardiologists...

10.20996/1819-6446-2013-9-1-4-14 article EN cc-by Rational Pharmacotherapy in Cardiology 2013-01-01

A problem of synonymy and synonyms legitimation is big importance in practice, as multiple classifications lead to problems organization provision medical care, incorrect statistics. The article a consensus experts on the issue agreement/implementation clinical classifying terms listed ICD-10, agreement modern morphological terms.

10.15829/1560-4071-2017-3-63-71 article EN cc-by Russian Journal of Cardiology 2017-03-25

Aim. To study a pattern of concomitant cardiovascular diseases (CVDs) and to estimate particularities quality medical antihypertensive therapy in hypertensive patients real outpatient practice with help the Registry Ryazan region. Material methods. A total 3690 hypertension, ischemic heart disease, chronic failure atrial fibrillation, who had attended general practitioners cardiologists 3 clinics city, were enrolled (RECVASA). The diagnosis hypertension was recorded 3648 (98.9%) charts,...

10.20996/1819-6446-2016-12-1-4-15 article EN cc-by Rational Pharmacotherapy in Cardiology 2016-03-09

Обоснование.Проблема лечения больных с терминальной стадией хронической почечной недостаточности обусловлена постоянно растущим количеством пациентов, нуждающихся в программном гемодиализе и высокой частоте осложнений, связанных функционированием постоянного сосудистого доступа.В настоящее время нет идеального доступа для гемодиализа.Основными причинами, которые приводят к прекращению его функционирования необходимости выполнения повторных операций являются развитие стенозов артериовенозных...

10.23888/hmj20197179-85 article RU Nauka molodykh (Eruditio Juvenium) 2019-03-30

BACKGROUND: Data on the peculiarities of clinical presentation and characteristics pulmonary embolism (PE) problems its diagnosis in routine practice (CP) are limited. obtained long ago mostly described terms venous thromboembolism general practically do not include Russian patients with PE. The study was performed within RusSIan REgistery pulmoNAry (SIRENA) register.
 AIM: To demographic profile PE modern CP comparison results other registers.
 MATERIALS AND METHODS: In this...

10.17816/pavlovj85405 article EN I P Pavlov Russian Medical Biological Herald 2022-03-31

The modern principles of myocardial infarction diagnosis formulation, recording, and statistical coding are discussed in the article. It contains material on terminology, clinical classifications practical aspects use 10th revision International classification diseases related health problems.

10.18565/cardio.2016.9.60-66 article EN Kardiologiia 2016-09-27

This article deals with the knowledge re-using and organization of decision support systems. Management organizations enterprises as complex dynamic systems in modern conditions is impossible without using information technology. The problem most relevant, since it allows you to organize mechanism making involving domain experts. Due knowledge, engineering costs development time are reduced project quality increases. describes a method forming an ontological description interactive...

10.18287/2223-9537-2017-7-1-48-65 article EN Ontology of Designing 2017-01-01

Pulmonary embolism (PE) is the third most common cardiovascular disease after myocardial infarction and stroke, one of leading causes death in Europe.
 Aim. Analysis modern scientific base concerning possibilities limitations use anticoagulant therapy (ACT) at different stages medical care PE depending on risk stratification. The article reflects position Clinical guidelines, results recent studies some controversial unresolved issues ACT for PE.
 Conclusion. Currently, a...

10.23888/pavlovj201927193-106 article EN I P Pavlov Russian Medical Biological Herald 2019-04-02

Цель.Оценить частоту тревоги/депрессии в Рязанском регионе и ее связь с хроническими неинфекционными заболеваниями их неблагоприятными исходами течение 36 месяцев.Материал методы.В исследование МЕРИДИАН-РО было включено 1622 человека (1220 городского 402 -сельского населения) возрасте 25-64 лет, из которых 750 (42,6%) были мужчины, 872 (53,8%) -женщины.Отклик на составил 86,1%.Результаты.Частота клинически значимой общей выборке составила 62,0%, при этом 5,2% испытывали сильную...

10.23888/hmj20197128-37 article RU Nauka molodykh (Eruditio Juvenium) 2019-03-30

Aim . To assess the incidence of adverse outcomes and role main risk factors in their development. Material methods Prospective, long-term study was conducted with observation period 36 months. The sample MERIDIAN-RO formed from urban rural population. It included 1622 people aged 25-64 years. response to 86,1%. Observation screening endpoints continued for were: all-cause death, ischemic stroke, myocardial infarction, coronary artery revascularization. Results When studying relationship...

10.15829/1560-4071-2019-6-42-48 article EN cc-by Russian Journal of Cardiology 2019-07-08

Aim. Analysis of the relevance drug-induced bradycardia (DIB) as a medical and social problem, its main regularities determination need for further study this issue.
 Materials Methods. The register was performed on 01 Jan 2017-30 Jun 2018 (18 months) at clinical base Ryazan Regional Clinical Cardiology Dispensary. Inclusion criteria were: 1) bradycardia/bradyarrhythmia syndrome with intake least one drug bradycardic effect (BCE), 2) signing Informed consent to processing personal data....

10.23888/pavlovj2020282153-163 article EN I P Pavlov Russian Medical Biological Herald 2020-07-03

Basing on the analysis of a registry study, usage diagnostic methods in patients with coronary heart disease outPatient setting, and their comPliance guidelines Russian Society Cardiology were assessed. An outpatient included 3672 hypertension, disease, failure atrial fibrillation who aPPealed to theraPist or cardiologist for medical aid. High incidence rate CHD hypertension (98.9 %) CHF (91.3 was registered study. The revealed lack active follow-up by therapists cardiologists, insufficient...

10.17816/pavlovj2014190-96 article EN I P Pavlov Russian Medical Biological Herald 2014-12-15

INTRODUCTION: Despite the recently established evidence-based and systemic approach to treatment for arterial hypertension (AH), not in all cases its control can be achieved.
 AIM: To conduct a comparative analysis of concentration antihypertensive drugs (AHTDs) blood serum patients with controlled uncontrolled AH.
 MATERIALS AND METHODS: Fifty six were included. Inclusion criteria: age 18 years, signing informed consent, diagnosis AH, regular intake any two study (lisinopril,...

10.17816/pavlovj119880 article EN I P Pavlov Russian Medical Biological Herald 2023-07-16

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10.4314/phmedj.v3i3.45267 article EN Port Harcourt Medical Journal 2009-08-24

Aim. To study gender and age characteristics of incidence rate, mortality lethality in acute coronary heart disease (ACHD). Material Methods. Analysis the ACHD (ICD-10 codes: I21.0-I22.9, I20.0, I24) morbidity, lethality, depending on sex was performed population (n=285 736; 46% men) several city administrative districts Voronezh, Ryazan Khanty-Mansiysk. Morbidity, were calculated basis medical documentation as well cases identified by protocol. Results. The morbidity men 1.99 1.79 times...

10.20996/1819-6446-2010-6-5-639-644 article EN cc-by Rational Pharmacotherapy in Cardiology 2010-01-01

Purpose: The aim of the study was to evaluate trends in incidence acute myocardial infarction (AMI) Kaunas population aged 25-64 years during 1998 2008.Methods: source data is population-based ischemic heart disease (IHD) register.The methods used for collection were those applied by WHO MONICA project.The object all permanent residents who had AMI and died from IHD 1998-2008.The age-standardized rates calculated direct method using Segi's world as a standard.Trends analyzed linear...

10.1177/1741826711407011 article EN European Journal of Cardiovascular Prevention & Rehabilitation 2011-03-29

INTRODUCTION: Pulmonary embolism (PE) is a cardiovascular disease with high mortality: according to autopsy data, PE the cause of death in every tenth deceased person. Despite relatively long history studying PE, literature data on this problem are scattered, incomplete and often do not represent Russian population.
 AIM: To evaluate 12-month survival rate patients after past episode establish predictors fatal outcome.
 MATERIALS AND METHODS: The work was carried out within SIRENA...

10.17816/pavlovj165196 article EN I P Pavlov Russian Medical Biological Herald 2023-04-03

The study analyzes the influence on prognosis of blockade right bundle branch block in patients with acute myocardial infarction. Score prognostic value was carried out comparison a group without intraventricular conduction disturbances, and left block. Established negative effect infarction, this maintained after 30 days year, 3 years.

10.17816/pavlovj2012394-99 article EN I P Pavlov Russian Medical Biological Herald 2012-12-15
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