A5052283794- Nutrition and Health in Aging
- Cancer survivorship and care
- Frailty in Older Adults
- Body Composition Measurement Techniques
- Cancer Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Childhood Cancer Survivors' Quality of Life
- Bone health and treatments
- Family Support in Illness
- Cancer Immunotherapy and Biomarkers
- Nutrition, Genetics, and Disease
- Obesity and Health Practices
- Cutaneous Melanoma Detection and Management
- Cancer, Lipids, and Metabolism
- Multiple and Secondary Primary Cancers
- Nutritional Studies and Diet
- Stoma care and complications
- Esophageal Cancer Research and Treatment
- Diet and metabolism studies
- Cancer Risks and Factors
- Palliative Care and End-of-Life Issues
- Inflammatory Biomarkers in Disease Prognosis
- Esophageal and GI Pathology
- Prostate Cancer Treatment and Research
- Regulation of Appetite and Obesity
University College Cork
2014-2024
Food & Nutrition
2024
Food for Health Ireland
2020
St. James's Hospital
2017
Technical Data Analysis (United States)
2017
Immune Regulation (United Kingdom)
2017
Murphy Oil Corporation (United States)
2017
Providence Milwaukie Hospital
2015
Malnutrition, weight loss, and muscle wasting are common in patients with foregut cancers (oesophagus, stomach, pancreas, liver, bile ducts) associated adverse clinical outcomes. However, little is known about the changes body composition that occur these during chemotherapy its impacts outcomes.A prospective study of adult cancer undergoing between 2012 2016 was conducted. Computed tomography images were evaluated for cross-sectional skeletal area (SMA) adipose tissue (ATA) at two time...
Body composition is an important predictor of drug toxicity and outcome. Ipilimumab (Ipi), a monoclonal antibody used to treat metastatic melanoma, has specific toxicities. No validated biomarkers that predict Ipi efficacy exist. Also, the impact on body not been established. Patients with melanoma treated between 2009 2015 were included. was assessed by computed tomography at baseline after four cycles Ipi. Sarcopenia low muscle attenuation (MA) defined using published cut-points. All...
Abstract Background Nutrition screening on admission to hospital is mandated in many countries, but date, there no consensus which tool optimal the oncology setting. Wasting conditions such as cancer cachexia (CC) and sarcopenia are common patients negatively impact outcomes; however, they often masked by excessive adiposity. This study aimed inform application of populations investigating whether commonly used nutritional tools adequately capturing nutritionally vulnerable patients,...
Sunitinib is a standard first-line option for metastatic renal cell carcinoma (mRCC). Body composition prognostic factor in cancer patients and with loss of skeletal muscle mass fat-free (FFM) are prone to dose-limiting toxicity (DLT) during targeted drug therapy. We investigated whether body by computed tomography predicted DLT from sunitinib mRCC.Patients clear mRCC receiving (50 mg) were included. Skeletal cross-sectional area at L3 was measured tomography. Sarcopenia defined using...
Background Optimizing quality of life (QoL) remains the central tenet care in patients with incurable cancer; however, determinants QoL are not clear. The objective current study was to examine which factors influence cancer. Methods A multicenter adult advanced cancer conducted Ireland and United Kingdom between 2011 2016. Data were collected from at entry included patient demographics, Eastern Cooperative Oncology Group performance status (ECOG‐PS), nutritional parameters (the percentage...
Objective: This randomized controlled trial (RCT) hypothesized that prolonged enteral nutrition (EN) with supplemental eicosapentanoic acid (EPA), an omega-3 fatty immune and anabolic properties, may impact on clinical nutritional outcomes. Background: Esophagectomy is associated significant weight loss catabolism, negatively impacts quality of life (QL). Strategies to counter sustained catabolism have therapeutic rationale. Methods: multicenter, double-blind, placebo-controlled RCT was...
Abstract Background Weight loss (WL) has long been recognized as an important factor associated with reduced quality of life (QoL) and survival in patients cancer. The body mass index (BMI)‐adjusted weight grading system (WLGS) shown to be survival. However, its impact on QoL not established. aim this study was assess the relationship between WLGS advanced Methods A biobank analysis undertaken adult Data collected included patient demographics, Eastern Cooperative Oncology Group performance...
Background The significant increase in cancer survivorship rates necessitates a comprehensive, multidisciplinary approach to supportive care services. This study seeks assess the feasibility of introducing Men’s Health Initiative intervention program Ireland. Methods is single-arm involving 12-week men’s programme alongside routine follow-up patients with advanced genitourinary malignancies. Men advanced/metastatic (including prostate, kidney, urothelial tract, testicular or penile cancer),...
Malnutrition is a frequent, undiagnosed complication in cancer patients and associated with negative prognosis. Screening allows for early identification of malnutrition appropriate nutrition assessment may lead to beneficial outcomes nutritional status quality life. The author conducted review the literature identify tools screening patients. An overview relevance these clinical practice discussed. This article designed help dietitians choose oncology
Abstract Background Oral health is affected by dietary practices and may impact quality of life. Collaboration between dietetics dental professionals for oral promotion disease prevention recommended. The present study aimed to determine the knowledge practice dentists dietitians on diet health. Methods comprised a cross‐sectional online questionnaire, which was disseminated electronically in UK Ireland, via national networks. Questions assessed participants’ cariogenicity different foods,...
10137 Background: Malnutrition negatively impacts clinical outcomes in cancer pts. The prevalence of malnutrition Irish oncology pts is unknown. Our aim was to assess the nutritional status this cohort and impact on quality life (QOL) survival. Methods: A cross sectional study out-pts presenting for chemotherapy between 2012–2016 at 2 university teaching hospitals performed. survey devised, incorporating clinical, nutritional, biochemical QOL data. Nutritional evaluated using cachexia...
Malnutrition and body composition predict poor quality of life reduced survival in ambulatory oncology patients receiving chemotherapy: a cross sectional study 1015 - Volume 77 Issue OCE1
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Women diagnosed with a hormone-receptor positive (HR+) breast or gynaecological cancer are not routinely prescribed hormone replacement therapy to alleviate menopausal symptoms due the risk of causing recurrence. Many these women use herbal botanical supplements, diet and lifestyle interventions provide relief. Through an extensive literature review, national focus groups female survivors, consultation established public patient involvement panel, creation review panel medical healthcare...
1505 Background: Expert consensus supports a multidisciplinary strategy in cancer survivorship care to enhance patient outcomes and quality of life. We hypothesized that introducing women’s clinic into routine follow up would be feasible, associated with improved symptom management life (QOL). Methods: LYSA was multisite randomized controlled trial parallel arms (experimental active comparator), co-designed public involvement. Eligibility: early-stage hormone receptor-positive breast or...
Background The improved survival rate for many cancers in high-income countries demands a coordinated multidisciplinary approach to survivorship care and service provision ensure optimal patient outcomes quality of life. This study assesses the feasibility introducing Men’s Health Initiative supportive intervention programme Ireland. Methods is single-arm involving 12-week men’s cancer alongside routine follow-up patients with advanced genitourinary malignancies. Men advanced/metastatic...