- Parathyroid Disorders and Treatments
- Cancer survivorship and care
- Nutrition and Health in Aging
- Folate and B Vitamins Research
- Occupational and environmental lung diseases
- Vitamin D Research Studies
- Air Quality and Health Impacts
- Family Support in Illness
- Nanowire Synthesis and Applications
- Nanoparticles: synthesis and applications
- Advanced biosensing and bioanalysis techniques
- Anodic Oxide Films and Nanostructures
- Childhood Cancer Survivors' Quality of Life
- Genetic Syndromes and Imprinting
- Magnesium in Health and Disease
- Magnetic and Electromagnetic Effects
- Bone and Joint Diseases
- Advanced machining processes and optimization
- Electrohydrodynamics and Fluid Dynamics
- Electrodeposition and Electroless Coatings
- Health Services Management and Policy
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Education
- Ionic liquids properties and applications
- Pharmacovigilance and Adverse Drug Reactions
Leeds Teaching Hospitals NHS Trust
2023-2025
Cork University Hospital
2008-2024
Health Research Board
2020-2021
University College Cork
2017-2021
The Francis Crick Institute
2021
Trinity College Dublin
1961-2012
Suspicion has been raised that high aspect ratio nanoparticles or nanofibers might possess asbestos-like pathogenicity. The pleural space is a specific target for disease in individuals exposed to asbestos and by implication of nanofibers. Pleural effects fibers depends on fiber length, but the key threshold length beyond which adverse occur never identified till now because all vitreous samples are heterogeneously distributed their length. Nanotechnology advantageously allows highly defined...
The use of fibre-shaped nanomaterials in commercial applications has met with concern that they could cause health effects similar to those seen pathogenic fibres such as certain forms asbestos. Of the attributes which form fibre pathogenicity paradigm, length is thought be a critical factor determining toxicity. We have previously shown carbon nanotubes display length-dependent but it remains unclear if other fibrous conform paradigm. As such, our aim determine generality this hypothesis by...
Abstract Objectives To establish our first Infection Summit, aiming to engage and educate non-infection specialists locally improve antimicrobial stewardship (AMS) identify quality improvement (QI) ideas AMS interventions, through collaboration. also gather feedback determine any benefits of this trust-wide event. Methods LTHT did not meet the NHS standard contract targets for consumption in 2023–24 so Summit was created implemented. A wide variety healthcare professionals from 14 different...
It is possible to suppress convection and dispersion of a paramagnetic liquid by means magnetic field. A tube can be stabilized in water along ferromagnetic track vertical field, but not horizontal Conversely, an “antitube” the same transverse The stability arises from interaction induced moment solution with field gradient vicinity track. force causes behave as if it were encased elastic membrane whose cross-section modified gravitational forces Maxwell stress. Convection its surroundings...
Abstract Flow cytometry is one of the gold‐standard techniques used in clinical medicine for quantitative immunoassaying. The continuous development its probes, commonly fluorescent nanoparticles, important. Lately, introduction multiplexed immunoassay has challenged use nanoparticles as probes. Functionalized silica‐based magnetic nanowires are investigated under flow a novel probe category. preparation and full characterization these multimodal reported compared to those by cytometry. Full...
The standard low-phosphorus diet restricts pulses, nuts, and whole grains other high phosphorus foods to control hyperphosphatemia. We conducted a randomized controlled trial evaluate the effectiveness, safety, tolerability of modified diet, which introduced some pulses increased use grains, focus on avoidance phosphate additives, prescription low-biological-value protein such as bread.We multicenter, pragmatic, parallel-arm, open-label, versus in 74 adults hemodialysis with...
<i>Background:</i> The relationship between calcium intake and serum level in hemodialysis patients is poorly understood. <i>Methods:</i> We quantify total oral using detailed 7-day food diaries with 294 patient days of observation 42 stable, non-diabetic subjects. <i>Results:</i> Mean (SD) albumin-corrected was 9.84 mg/dl (0.8). low (<8.4 mg/dl) 2 patients, low-normal (8.4–9.49) 9 high-normal (9.5–10.2) 18 high (>10.2) 13 patients. (diet plus...
Equiatomic CoPt nanowires with a gold cap layer have been fabricated by electrochemical template synthesis. Au improves the structural and magnetic properties of L10 ordered CoPt, leading to coercivities up 1.43 T. The anisotropy constant K1 was estimated as 3.9(9) MJ m−3 from approach saturation, four effective constants were determined analysis torque curves in 14 T field. Multisegmented are produced using interlayers.
<ns3:p><ns3:bold>Background: </ns3:bold>Potential dietary strategies for controlling hyperphosphataemia include the use of protein sources with lower phosphorus bioavailability such as pulses and nuts, focus on to ratios avoidance all phosphate additives.</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> We conducted a controlled crossover feeding study in 8 haemodialysis (HD) patients investigate acute postprandial effect modified versus standard low diet one day serum phosphate, potassium...
Introduction: Although older individuals are more prone to hypoglycaemia, it is not known if they have sufficient understanding of the risks hypoglycaemia or factors that predispose it. We evaluated effectiveness education and examined increased susceptibility among people with diabetes. Methods: Forty-five patients (male/female) aged >65 years diabetes were identified through outpatient clinics at a secondary care hospital. Information relating received, awareness associated risk was...
1505 Background: Expert consensus supports a multidisciplinary strategy in cancer survivorship care to enhance patient outcomes and quality of life. We hypothesized that introducing women’s clinic into routine follow up would be feasible, associated with improved symptom management life (QOL). Methods: LYSA was multisite randomized controlled trial parallel arms (experimental active comparator), co-designed public involvement. Eligibility: early-stage hormone receptor-positive breast or...
Abstract CAPTURE (NCT03226886) is a prospective cohort study of COVID-19 immunity in patients with cancer. Here we evaluated 585 following administration two doses BNT162b2 or AZD1222 vaccines, administered 12 weeks apart. Seroconversion rates after were 85% and 59% solid hematological malignancies, respectively. A lower proportion had detectable neutralizing antibody titers (NAbT) against SARS-CoV-2 variants concern (VOCs) vs wild-type (WT). Patients malignancies more likely to have...
Abstract Background The improved survival rate for many cancers in high-income countries demands a coordinated multidisciplinary approach to survivorship care and service provision ensure optimal patient outcomes quality of life. This study assesses the feasibility introducing Women’s Health Initiative cancer clinic Ireland. Methods trial comprises an intervention control arm. Two hundred participants will be recruited. Key eligibility (1) women with early-stage hormone receptor-positive...