A5009269339- Ethics in Clinical Research
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Obesity, Physical Activity, Diet
- Obesity and Health Practices
- Patient-Provider Communication in Healthcare
- Suicide and Self-Harm Studies
- Thermal Regulation in Medicine
- Mental Health and Patient Involvement
- Health Policy Implementation Science
- Mobile Health and mHealth Applications
- Bariatric Surgery and Outcomes
- Healthcare cost, quality, practices
- Substance Abuse Treatment and Outcomes
- Behavioral Health and Interventions
- Viral Infections and Vectors
- Health and Medical Research Impacts
- Adolescent Sexual and Reproductive Health
- Parathyroid Disorders and Treatments
- Clinical practice guidelines implementation
- Reproductive Health and Technologies
- Nutritional Studies and Diet
- Cancer Genomics and Diagnostics
- Alcohol Consumption and Health Effects
- Nutrition and Health in Aging
University College Cork
2016-2025
Trials Methodology Research Network
2023-2024
Health Research Board
2016-2024
National University of Ireland
2020-2023
Weatherford College
2023
University of Aberdeen
2023
Mercy University Hospital
2016-2021
ORCID
2021
University of Washington
2009-2010
Harborview Medical Center
2010
There is considerable evidence of a cultural shift towards heavier alcohol consumption among university students, especially women. The aim this study to investigate the prevalence and correlates hazardous (HAC) students with particular reference gender compare different modes data collection in population.A large Irish university.A cross-sectional using classroom distributed paper questionnaire.A total 2275 undergraduates completed survey, 84% those class 51% registered for relevant...
Multi-morbidity and polypharmacy increase the risk of non-trivial adverse drug reactions (ADRs) in older people during hospitalization. Despite this, there are no established interventions for hospital-acquired ADR prevention.We undertook a pragmatic, multi-national, parallel arm prospective randomized open-label, blinded endpoint (PROBE) controlled trial enrolling patients at six European medical centres. We 1,537 surgical with multi-morbidity on admission 1:1 ratio to SENATOR...
Randomised trials, especially those intended to directly inform clinical practice and policy, should be designed reflect all who could benefit from the intervention under test it prove effective. This does not always happen. The UK National Institute for Health Care Research (NIHR) INCLUDE project identified many groups in that are under-served by including ethnic minorities.This guidance document presents four key recommendations designing running trials include needed trial. These (1)...
The combination of four protective lifestyle behaviours (being physically active, a non-smoker, moderate alcohol consumer and having adequate fruit vegetable intake) has been estimated to increase life expectancy by 14 years. However, the effect adopting these on general health, obesity mental health is less defined. We examined combined self-rated overweight/obesity depression.Using data from Survey Lifestyle Attitudes Nutrition (SLAN) 2007 (), behaviour (PLB) score was constructed for...
Background We have previously identified in a study of both self-reported body mass index (BMI) and clinically measured BMI that the sensitivity score obese category has declined over 10-year period. It is known weight significantly lower height higher than height. The purpose this to establish if bias or bias, both, responsible for declining between BMI. Methods report on from three waves Surveys Lifestyle Attitudes Nutrition (SLÁN) involving nationally representative sample Irish adults....
Abstract There is a dearth of literature on best practices for managing clinical trials, and little understood the role trial manager. The COVID-19 pandemic has brought this into focus, continuance trials worldwide been catapulted state uncertainty as countries enter lockdown to manage spread virus. Participant retention an ongoing issue in concern that current environment, attrition will be which could potentially jeopardise completion. situation necessitated timely problem solving by...
ObjectiveTo estimate the extent of under- and over-reporting, to examine associations with misreporting sociodemographic lifestyle characteristics mental health status identify differential reporting in micro- macronutrient intake quality diet.DesignA questionnaire a semi-quantitative FFQ were completed as part 2007 Survey Lifestyle, Attitudes Nutrition. Energy (EI) macronutrients determined by applying locally adapted conversion software. A dietary score was constructed healthier diets....
Randomised trials support improved decision-making through the data they collect. One important piece of is primary outcome - so called because it what investigators decide most important. Secondary outcomes provide additional information to decision-making. We were interested in knowing how patients and healthcare professionals consider (especially outcome) measured a selection published trials.The work had three stages: (1) identified body late-stage two clinical areas, breast cancer...
Objectives The purpose of our study was to determine the order in which science and health researchers read scientific papers, their reasons for doing so perceived difficulty importance each section. Study design setting An online survey open academics distributed via existing research networks, X (formerly Twitter), LinkedIn. Results Almost 90% respondents self-declared be experienced reading papers. 98.6% sample abstract first because it provides an overview paper facilitates a decision on...
As the use of self-reported data to classify obesity continues, temporal change in accuracy self-report measurement when compared clinical remains unclear. The objective this study was examine trends misclassification patterns, as well sensitivity and specificity, clinically measured versus based body mass index (BMI) from three national lifestyle surveys over a 10-year period. Surveys Lifestyle Attitudes Nutrition (SLÁN) were interview cross-sectional survey/measurements involving...
Fever and febrile illness are some of the most common conditions managed by parents. The aim this study was to examine knowledge, attitudes beliefs parents around fever in children under five years age.Between July August 2014, a convenience sample invited participate Copenhagen, Denmark. Results were analysed thematically using constant comparison method.Twenty-one participated study. Five themes emerged from data: parental concern, help-seeking behaviour, parent management practices...
Fever is one of the most common childhood symptoms. It causes significant worry and concern for parents. Every year there are numerous cases over- under-dosing with antipyretics. Caregivers seek reassurance from a variety sources including healthcare practitioners. The aim this study was to describe parental knowledge, attitudes beliefs regarding management fever in children aged 5 years under. Semi-structured interviews were conducted 23 parents at six ante-natal clinics south west Ireland...
Objectives Fever is a common symptom of mostly benign illness in young children, yet concerning for parents. The aim this study was to describe parental knowledge, attitudes and beliefs regarding fever children aged ≤5 years age. Design A cross-sectional using previously validated questionnaire. Results were analysed descriptive statistics multivariable logistic regression. Setting Purposively selected primary schools (n=8) Cork, Ireland, paper-based Data collected from internet-based...
<title>Abstract</title> Background Randomised trials often struggle with recruitment, retention, and delays, impacting both finances patient care. To improve trial processes, trialists can do Studies Within A Trial (SWATs) that compare process alternatives. Although SWATs are recognized by funders, there differences in how they implemented, such as different consent requirements the UK Ireland. This complicates SWAT conduct, raises ethical considerations, highlights need for standardised,...
Improving clinical trial inclusivity for diverse populations, including people with disabilities, is crucial. Ethical considerations emphasize the need enrollment to mirror potential users' diversity, yet underrepresentation persists due direct and indirect exclusions. The purpose of our study was determine if teams collect data on disabilities diversity monitoring purposes. We also examined how they disability report it. reviewed reports randomized controlled trials published in UK National...
Virtual reality (VR) is potentially effective in raising awareness of testicular diseases, promoting self-examination and early help-seeking among men. This paper presents an economic evaluation exploring the potential cost-effectiveness Enhancing Men's Awareness Testicular diseases (E-MAT)VR, a VR interactive experience compared with E-MATE, electronic information, male athletes Results from this will inform support design future randomized controlled trial (RCT). Irish feasibility...
We previously published a study examining the risk of bias random selection Cochrane systematic reviews. The purpose our current is to reassess cohort reviewed trials see if reassessment differs from original assessment and determine whether funder, having methodological support, or involving statistician affected bias. extracted data 140 159 included three countries, UK, Canada, Ireland, in cohort. 19 remaining were excluded for variety reasons. recorded number participants trial, was...