Christopher L. Deufel

ORCID: 0000-0001-8595-3289
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About
Contact & Profiles
Research Areas
  • Advanced Radiotherapy Techniques
  • Prostate Cancer Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Ocular Oncology and Treatments
  • Radiation Dose and Imaging
  • Radiation Therapy and Dosimetry
  • Prostate Cancer Treatment and Research
  • Breast Cancer Treatment Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Glaucoma and retinal disorders
  • Glioma Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Endometrial and Cervical Cancer Treatments
  • Advanced X-ray and CT Imaging
  • Orbital Angular Momentum in Optics
  • Management of metastatic bone disease
  • Nail Diseases and Treatments
  • Cutaneous lymphoproliferative disorders research
  • Photoacoustic and Ultrasonic Imaging
  • Surgical Simulation and Training
  • Advances in Oncology and Radiotherapy
  • Fungal Infections and Studies
  • Radiation Effects and Dosimetry
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Diagnosis and Treatment

Mayo Clinic in Arizona
2016-2025

Mayo Clinic
2014-2024

Advanced Radiation Therapy (United States)
2023-2024

Gynecologic Oncology Group
2023-2024

WinnMed
2014-2024

NYU Langone Health
2023-2024

Stellar Science (United States)
2023-2024

Spanish Oncology Genitourinary Group
2023-2024

Memorial Sloan Kettering Cancer Center
2023

Mayo Clinic in Florida
2017-2021

The response of single DNA molecules to externally applied forces and torques was directly measured using an angular optical trap. Upon overwinding, buckled abruptly as revealed by a sharp extension drop followed torque plateau. When the held at buckling transition, its hopped rapidly between two distinct states. Furthermore, initial plectonemic loop absorbed approximately twice much into plectoneme upon each additional turn. observed change after postbuckling support recent elasticity model.

10.1103/physrevlett.100.148301 article EN Physical Review Letters 2008-04-08

PurposeHistorically, the standard of care for total skin electron beam therapy (TSEBT) delivered 30 to 36 Gy over 5 10 weeks. Given high risk relapse, a majority patients require additional treatments. Therefore, attempts use shortened course TSEBT have been investigated.Methods and MaterialsWe conducted single-institution retrospective review evaluate disease response, control, toxicity using low-dose, hypofractionated (HTSEBT) in with mycosis fungoides.ResultsForty received 57 courses...

10.1016/j.prro.2020.08.001 article EN cc-by-nc-nd Practical Radiation Oncology 2020-08-08

A total skin electron (TSE) floor technique is presented for treating patients who are unable to safely stand extended durations. customized flattening filter used eliminate the need field junctioning, improve uniformity, and reduce setup time. The constructed from copper polycarbonate, fits into linac's accessory slot, optimized extend useful height width of beam such that no junctions needed during treatment. TSE with (TSE FF) treatment course consisted six patient positions: three supine...

10.1120/jacmp.v14i5.4309 article EN cc-by Journal of Applied Clinical Medical Physics 2013-09-01

. An algorithm was developed for automated positioning of lattice points within volumetric modulated arc radiation therapy (VMAT LRT) planning. These are strategically placed the gross tumor volume (GTV) to receive high doses, adhering specific separation rules from adjacent organs at risk (OARs). The study goals included enhancing planning safety, consistency, and efficiency while emulating human performance.

10.1088/1361-6560/ad2ee8 article EN Physics in Medicine and Biology 2024-02-29

Health leaders have advocated for incident learning systems (ILSs) to prevent errors, but there is limited evidence demonstrating that ILSs improve cancer patient safety. Herein, we report a long-term retrospective review of ILS reports the brachytherapy practice at large academic institution.Over nine-year period, was encouraged all standard operating procedure deviations, including low risk deviations. A multidisciplinary committee assigned root causes and scores incidents. Evidence based...

10.1016/j.radonc.2017.07.032 article EN cc-by-nc-nd Radiotherapy and Oncology 2017-08-17

Cholangiocarcinoma patients who are potential candidates for liver transplantation may be treated with high-dose-rate (HDR) brachytherapy using a minimally invasive nasobiliary catheter in an effort to escalate the radiotherapy dose tumor and maximize local control rates. This work describes equipment, procedures, quality assurance (QA) that enables successful administration.This placement, simulation, treatment planning, delivery, QA. In addition, chart review was performed of all received...

10.1016/j.brachy.2018.03.006 article EN cc-by-nc-nd Brachytherapy 2018-06-20

As dose optimization for high rate brachytherapy becomes more complex, it increasingly important to have a means of verifying that results are reasonable. A method is presented using simple as quality assurance the complex algorithms typically found in commercial treatment planning systems. Quality tests may be performed during commissioning, at regular intervals, and/or on patient specific basis. provided optimizes conformal target coverage an exact, variance-based, algebraic approach....

10.1088/0031-9155/59/3/525 article EN Physics in Medicine and Biology 2014-01-17
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