A5024662261- Breast Cancer Treatment Studies
- Advanced Radiotherapy Techniques
- Effects of Radiation Exposure
- Advances in Oncology and Radiotherapy
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Nonmelanoma Skin Cancer Studies
- Radiation Therapy and Dosimetry
- Prostate Cancer Diagnosis and Treatment
- Ocular Oncology and Treatments
- Head and Neck Cancer Studies
- Management of metastatic bone disease
- Chemotherapy-related skin toxicity
- Cancer Risks and Factors
- Innovations in Medical Education
- Radiology practices and education
- Radiation Dose and Imaging
- Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Prostate Cancer Treatment and Research
- Cancer survivorship and care
- Cancer Treatment and Pharmacology
- Healthcare professionals’ stress and burnout
- BRCA gene mutations in cancer
Mayo Clinic
2016-2025
Mayo Clinic in Arizona
2016-2025
Twitter (United States)
2025
WinnMed
2018-2023
Mayo Clinic in Florida
2021
University of Wisconsin–La Crosse
2019
Memorial Medical Center
2014
University of Chicago Medical Center
2013
University of Chicago
2010-2013
University of Rochester Medical Center
2008
Background Cancer staging and treatment presumes a division into localized or metastatic disease. We proposed an intermediate state defined by ≤5 cumulative metastasis(es), termed oligometastases. In contrast to widespread polymetastases, oligometastatic patients may benefit from metastasis-directed local treatments. However, many who initially present with oligometastases progress polymetastases. Predictors of progression could improve patient selection for therapy. Methods Here, we...
Rationale Strategies to stage and treat cancer rely on a presumption of either localized or widespread metastatic disease. An intermediate state metastasis termed oligometastasis(es) characterized by limited progression has been proposed. Oligometastases are amenable treatment surgical resection radiotherapy. Methods We analyzed microRNA expression patterns from lung samples patients with ≤5 initial metastases resected curative intent. Results Patients were stratified into subgroups based...
BackgroundDeveloping strategies to prevent breast cancer-related arm lymphoedema (BCRAL) is a critical unmet need because there are no effective interventions eradicate it once reaches chronic state. Certain such as prospective surveillance programs and prophylactic lymphatic reconstruction have been reported be in clinical trials. However, large variation exists practice based on clinician preference, organizational standards, local resources.MethodsA two-round international Delphi...
Objectives: Renal cell carcinoma (RCC) is considered radioresistant, but stereotactic radiosurgery can control intracranial metastases. Advances in radiotherapy, such as body radiotherapy (SBRT), allow high-dose radiation delivery to extracranial sites. Herein, we report our experience treating oligometastatic RCC with SBRT. Methods: Patients and limited metastases were treated on a 3-fraction dose-escalation protocol (8 14 Gy/fraction) or off 10 fractions (4 5 Gy/fraction). Disease was...
Reirradiation poses a distinct therapeutic challenge owing to risks associated with exceeding normal tissue tolerances and possibly more therapeutically resistant disease biology. We report our experience reirradiation for locoregional recurrent or second primary breast cancer.Between 1999 2019, all patients cancer treated repeat breast/chest wall radiation therapy (RT) at institution were identified. Adverse events assessed using the Common Terminology Criteria Events v5.0. Fisher exact,...
Abstract Background In breast cancer patients treated with pencil‐beam scanning proton therapy (PBS), the increased linear energy transfer (LET) near end of range can affect nearby ribs. This may associate a higher risk rib fractures. Purpose To study effect LET on fracture in PBS using novel tool dose‐LET volume histogram (DLVH). Methods From prospective registry post‐mastectomy to chest wall and regional lymph nodes for between 2015 2020, we retrospectively identified cases detected after...
Abstract Background and purpose To report dosimetry early adverse effects, aesthetic, patient-reported outcomes of a prospective study 3-fraction pencil-beam scanning (PBS) proton accelerated partial irradiation (APBI). Materials methods Eligibility included women age ≥ 50 years with estrogen receptor positive (ER+), sentinel lymph node negative invasive or in-situ breast cancer measuring ≤2.5 cm. The prescription was 21.9 Gy (RBE 1.1) in 3 daily fractions to the post-operative tumor bed 1...
To report oncologic, physician-assessed, and patient-reported outcomes (PROs) for a group of women homogeneously treated with modern, skin-sparing multifield optimized pencil-beam scanning proton (intensity modulated therapy [IMPT]) postmastectomy radiation (PMRT).We reviewed consecutive patients who received unilateral, curative-intent, conventionally fractionated IMPT PMRT between 2015 2019. Strict constraints were applied to limit the dose skin other organs at risk. Five-year oncologic...
Our aim was to report physician- and patient-reported outcomes of patients with localized breast cancer treated moderate versus ultrahypofractionated whole irradiation (WBI) after breast-conserving surgery (BCS).