A5010582439- Sarcoma Diagnosis and Treatment
- Cardiac tumors and thrombi
- Vascular Tumors and Angiosarcomas
- Advanced Radiotherapy Techniques
- Bone Tumor Diagnosis and Treatments
- Acute Myeloid Leukemia Research
- Childhood Cancer Survivors' Quality of Life
- Radiation Therapy and Dosimetry
- Management of metastatic bone disease
- Testicular diseases and treatments
- Breast Cancer Treatment Studies
- Lymphoma Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Surgical site infection prevention
- Nonmelanoma Skin Cancer Studies
- Neuroblastoma Research and Treatments
- Effects of Radiation Exposure
- Medical Imaging Techniques and Applications
- Urologic and reproductive health conditions
- Meningioma and schwannoma management
- Oral and Maxillofacial Pathology
- Breast Implant and Reconstruction
- Cardiac, Anesthesia and Surgical Outcomes
- Advances in Oncology and Radiotherapy
- Chemotherapy-related skin toxicity
Mayo Clinic in Arizona
2016-2025
Mayo Clinic Hospital
2023-2025
Mayo Clinic in Florida
2022-2025
WinnMed
2022-2025
All India Institute of Medical Sciences Bhubaneswar
2023-2024
Karachi Medical and Dental College
2024
Mayo Clinic
2013-2023
Command Hospital Air Force
2020-2021
The physical properties of protons lower doses to surrounding normal tissues compared with photons, potentially reducing acute and long-term adverse effects, including subsequent cancers. magnitude benefit is uncertain, however, currently based largely on modeling studies. Despite the paucity directly comparative data, number proton centers patients are expanding exponentially. Direct studies potential risks benefits needed in children, who have highest risk radiation-related Pediatric...
Local control for Ewing sarcoma (ES) has improved in modern studies. However, it is unclear if these gains have also been achieved pelvis tumors. The purpose of this study to evaluate local and survival ES patients treated the era.All diagnosed from 1990 2012 seen at Mayo Clinic were identified. Factors relevant analyzed.The cohort consisted 48 patients. Fifty-two percent had metastatic disease diagnosis. 5-year overall event-free was 73% 65%, respectively, localized disease. cumulative...
Objectives . To assess the clinical features and local control (LC) outcomes in adult patients with localized Ewing Sarcoma (ES). Methods The records of 102 ES disease ≥18 years age seen from 1977 to 2007 were reviewed. Factors relevant prognosis, survival, LC analyzed. Results. 5-year overall survival (OS) event-free (EFS) 60% 52%, respectively, for entire cohort. Treatment era (1977–1992 versus 1993–2007) remained an independent prognostic factor OS on multivariate analysis, improved...
Reirradiation poses a distinct therapeutic challenge owing to risks associated with exceeding normal tissue tolerances and possibly more therapeutically resistant disease biology. We report our experience reirradiation for locoregional recurrent or second primary breast cancer.Between 1999 2019, all patients cancer treated repeat breast/chest wall radiation therapy (RT) at institution were identified. Adverse events assessed using the Common Terminology Criteria Events v5.0. Fisher exact,...
Spatially fractionated radiation therapy (SFRT) is a recognized technique for enhancing tumor response in radioresistant and bulky tumors. We analyzed clinical treatment outcomes patients with bone soft tissue sarcomas treated modern SFRT techniques.
ABSTRACT Purpose Pulmonary toxicity (PT) remains a concern following total body irradiation (TBI). This study describes the incidence and factors associated with PT in cohort of patients homogeneously treated lateral opposed fields technique. Methods Medical records 61 ≤21 years age TBI as component stem cell transplantation from 1993–2017 were retrospectively reviewed. The incidences PT, graft‐versus‐host disease (GVHD), other toxicities recorded for each patient. was subdivided into its...
<h3>Importance</h3> Maximal resection is the preferred management for sacral chordomas but can be associated with unacceptable morbidity. Outcomes radiotherapy are poor. Carbon ion (CIRT) being explored as an alternative when surgery not preferred. <h3>Objective</h3> To compare oncologic outcomes and treatment-related toxicity of CIRT en bloc chordoma. <h3>Design, Setting, Participants</h3> Univariable logistic regression was performed to evaluate association between treatment type in this...
Surgical treatment of pelvic sarcoma involving the bone is standard care but associated with several sequelae and reduced functional quality life (QOL). Treatment photon proton radiotherapy relapse. Carbon ion (CIRT) may reduce both relapse rates sequelae. The PROSPER study a tricontinental, nonrandomized, prospective, three-arm, pragmatic trial evaluating treatments bone. Patients aged at least 15 years are eligible for inclusion. Participants must have an Eastern Cooperative Oncology Group...
Background Little data exist regarding long-term functional and quality of life (QOL) outcomes for survivors Ewing sarcoma (ES). Specifically, there are few reports assessing the impact patient characteristics local therapy modalities on patient-reported (PRO). Procedure Long-term ES treated between 1977 2009 completed self-assessed QOL surveys, using Toronto Extremity Salvage Score (TESS) PEDSQL 4.0 generic core instruments, respectively. Statistical analyses were performed to correlate...
Myxofibrosarcoma (MFS) is a subtype of soft tissue sarcoma with highly infiltrative growth pattern that leads to higher risk inadvertent positive surgical margins and local relapse. Poorly defined tumor also pose challenge for radiation therapy (RT) planning, in terms treatment volumes administration pre- versus postoperative RT. This study aims evaluate control patterns recurrence patients MFS treated neoadjuvant RT followed by definitive excision.
Extraskeletal Ewing sarcoma (EES), is a rare soft tissue sarcoma. Treatment for EES commonly involves chemotherapy and surgical resection (ST) or less combined chemotherapy, surgery, radiotherapy (ST + RT). The purpose of the current study was to evaluate our institutional experience treating EES.We reviewed 36 (18 males:18 females) patients (mean age 30 years) with nonretroperitoneal/visceral treated either ST (n = 24, 67%) RT 12, 33%). All were most vincristine, doxorubicin,...