A5083170859- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Advanced Radiotherapy Techniques
- Meningioma and schwannoma management
- Lung Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Ear and Head Tumors
- Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Colorectal and Anal Carcinomas
- Oral health in cancer treatment
- Thyroid Cancer Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Brain Metastases and Treatment
- Bone Tumor Diagnosis and Treatments
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Lung Cancer Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Oral and Maxillofacial Pathology
- Nonmelanoma Skin Cancer Studies
- Medical Imaging Techniques and Applications
- Adrenal and Paraganglionic Tumors
- Advances in Oncology and Radiotherapy
Mayo Clinic in Florida
2010-2024
WinnMed
2013-2024
Mayo Clinic
2015-2024
Mayo Clinic in Arizona
2015-2024
Arizona State University
2023
Fox Chase Cancer Center
2020
Neurological Surgery
2006-2019
Radiation Oncology Associates
1999-2018
Hudson Institute
2016
John Wiley & Sons (United States)
2016
Treatment is complex for patients with head and neck (H&N) cancers specific site of disease, stage, pathologic findings guiding treatment decision-making. planning H&N involves a multidisciplinary team experts. This article describes supportive care recommendations in the NCCN Guidelines Head Neck Cancers, as well rationale supporting new section on imaging cancers. also updates to very advanced salivary gland tumors, specifically systemic therapy recommendations.
<section class="abstract"><p id="P1">The NCCN Guidelines for Head and Neck (H&N) Cancers provide treatment recommendations cancers of the lip, oral cavity, pharynx, larynx, ethmoid maxillary sinuses, salivary glands. Recommendations are also provided occult primary H&N, separate algorithms have been developed by panel very advanced H&N cancers. These Insights summarize panel's discussion most recent regarding evaluation nasopharyngeal carcinoma. </section>
Forty-nine patients with esthesioneuroblastoma were treated at the Mayo Clinic between 1951 and 1990. Their clinical manifestations treatment results reviewed to identify possible prognostic factors. The 5-year survival rate for all was 69%. Tumor progression occurred in 25 (51%; no local control 6 recurrence 19). Metastasis found 15 (31%; regional 10 distant 9). Nineteen died directly from metastatic or intracranial tumor extension. pathological grade of most significant factor identified....
The best management for patients with small- to medium-sized vestibular schwannomas (VS) is controversial.: A prospective cohort study of 82 unilateral, unoperated VS less than 3 cm undergoing surgical resection (n = 36) or radiosurgery 46). Patients were younger (48.2 yr versus 53.9 yr, P 0.03). groups similar regard hearing loss, associated symptoms, and tumor size. mean follow-up period was 42 months (range, 12-62 mo).Normal facial movement preservation serviceable more frequent in the...
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Head and Neck Cancers provide treatment recommendations cancers of the lip, oral cavity, pharynx, larynx, ethmoid maxillary sinuses, salivary glands. Recommendations are also provided occult primary head neck (H&N), separate algorithms have been developed by panel very advanced H&N cancers. These Insights summarize panel's discussion most recent regarding increase human papillomavirus–associated oropharyngeal cancer...
These NCCN Guidelines Insights focus on recent updates to the 2015 for Head and Neck (H&N) Cancers. describe different types of particle therapy that may be used treat H&N cancers, in contrast traditional radiation (RT) with photons (x-ray). Research is ongoing regarding therapy, including protons carbon ions, goals reducing long-term side effects from RT improving therapeutic index. For update, Cancers Panel agreed delete recommendations neutron salivary gland because its limited...
Purpose To report results of a randomized phase II trial (Radiation Therapy Oncology Group RTOG-0234) examining concurrent chemoradiotherapy and cetuximab in the postoperative treatment patients with squamous cell carcinoma head neck (SCCHN) high-risk pathologic features. Patients Methods Eligibility required stage III to IV SCCHN gross total resection showing positive margins and/or extracapsular nodal extension two or more metastases. were randomly assigned 60 Gy radiation once per week...
The purpose of this study was to determine if dose de-escalation from 60 66 Gy 30 36 adjuvant radiotherapy (RT) for selected patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma could maintain historical rates disease control while reducing toxicity and preserving swallow function quality life (QOL).
In this study the authors sought to determine neurological risks and potential clinical benefits of gamma knife radiosurgery for skull base meningiomas.A consecutive series 88 patients harboring meningiomas were treated between 1990 1996 by using Leksell in a prospective that included strict dose-volume protocol. Forty-nine had previously undergone surgery, six received external-beam radiotherapy. The median treatment volume was 10 cm3, dose tumor margin 16 Gy. radiosurgical dosage optic...
Object. Each year a greater number of patients with trigeminal neuralgia (TN) undergo radiosurgery, including large who are candidates for microvascular decompression (MVD). Methods. The case characteristics and outcomes 117 consecutive underwent radiosurgery were retrieved from prospectively maintained database. mean patient age was 67.8 years; the majority (58%) had undergone surgery previously. dependent variable all analyses facial pain complete relief without medication (excellent...
Our aim was to evaluate the efficacy of stereotactic radiosurgery (SRS) for treatment patients with brain metastases that have been determined be "radioresistant" on basis histological examination.We reviewed medical records 41 consecutive who presented 83 from radioresistant primaries and subsequently underwent SRS. All were followed until death or a median 31 months after Tumor histologies included renal cell carcinoma (16 patients), melanoma (23 sarcoma (2 patients). Eighteen (44%) had...
Stereotactic radiosurgery is being used with more frequency in the management of patients trigeminal neuralgia. To improve facial pain outcomes, many centers have increased prescribed radiation dose to nerve.Between April 1997 and December 1999, 68 underwent for neuralgia use Leksell gamma knife (Elekta Instruments, Norcross, GA) a single 4-mm isocenter radiation. Twenty-seven (40%) received 70 Gy (low dose) irradiation 41 (60%) 90 (high dose). The groups were similar regard age, sex,...
Object. The goal of this study was to determine factors associated with endocrine normalization after radiosurgery is performed in patients hormone-producing pituitary adenomas. Methods. Between 1990 and 1999, 43 adenomas underwent radiosurgery: 26 growth hormone (GH)—producing tumors, nine adrenocorticotrophic hormone—producing seven tumors that produced prolactin (PRL) alone, one a tumor secreted both GH PRL. median patient age 42 years. Thirty-seven (86%) had undergone surgery earlier 30...
Background: Historical outcomes in anaplastic thyroid carcinoma (ATC) are poor, with a median survival of only 5 months and <20% patients surviving 1 year from diagnosis. We hypothesized that newly diagnosed stages IVA IVB locoregionally confined ATC might be improved by utilizing an aggressive therapeutic approach, prioritizing both the eradication disease neck preemptive treatment occult metastatic disease. Methods: Between January 1, 2003, December 31, 2007, 25 new were evaluated at our...
Abstract Background Patients with human papillomavirus–related oropharyngeal cancers have excellent outcomes but experience clinically significant toxicities when treated standard chemoradiotherapy (70 Gy). We hypothesized that functional imaging could identify patients who be safely deescalated to 30 Gy of radiotherapy. Methods In 19 patients, pre- and intratreatment dynamic fluorine-18-labeled fluoromisonidazole positron emission tomography (PET) was used assess tumor hypoxia. without...
The etiology and optimal treatment are unknown for angiosarcoma, an aggressive malignant tumor that affects vascular endothelial cells can be mistaken benign lesions such as hemangioma.To determine the outcomes of patients with angiosarcoma face or scalp treated a combination surgery, radiation therapy, and/or chemotherapy.Retrospective study 55 between January 1, 1973, December 31, 2012, at tertiary-care academic medical institution.Surgery, chemotherapy.Locoregional control (LRC),...
Anaplastic thyroid cancer (ATC) is rare and a highly fatal malignancy. The role of programmed death-1 (PD-1) death ligand-1 (PD-L1) as prognostic and/or predictive markers in ATC unknown. Multimodal therapy offers the best chance at tumor control. objective this study was to detect potential associations PD-1/PD-L1 axis variables with outcome data ATC. Retrospective uniformly treated cohort. Single institution retrospective cohort study. Sixteen patients who received intensity-modulated...