- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Occupational and environmental lung diseases
- Head and Neck Cancer Studies
- Palliative Care and End-of-Life Issues
- Pleural and Pulmonary Diseases
- Medical Imaging Techniques and Applications
- Effects of Radiation Exposure
- Management of metastatic bone disease
- Brain Metastases and Treatment
- Cancer Immunotherapy and Biomarkers
- Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Prostate Cancer Diagnosis and Treatment
- Radiation Detection and Scintillator Technologies
- Myasthenia Gravis and Thymoma
- Advances in Oncology and Radiotherapy
- Glioma Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Prostate Cancer Treatment and Research
New York Proton Center
2019-2025
Memorial Sloan Kettering Cancer Center
2019-2025
Health Sciences Centre
2024
Sunnybrook Health Science Centre
2024
Leiden University
2024
University of Maryland, Baltimore
2007-2023
University of Pennsylvania
2013-2023
Chinese People's Liberation Army
2023
Zhangzhou Municipal Hospital of Fujian Province
2023
Fujian Medical University
2023
Pathologic states within the prostate may be reflected by changes in serum proteomic patterns. To test this hypothesis, we analyzed mass spectra with a bioinformatics tool to reveal most fit pattern that discriminated training set of sera men histopathologic diagnosis cancer (serum prostate-specific antigen [PSA] > or =4 ng/mL) from those without PSA level <1 ng/mL). Mass blinded (N = 266) derived were matched against discriminating revealed set. A predicted benign disease was rendered based...
To our knowledge, there have been no clinical trials of ultra-high-dose-rate radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human use proton FLASH.To assess the workflow feasibility and treatment-related toxic effects pain relief treatment sites.In FAST-01 nonrandomized trial, participants treated Cincinnati Children's/UC Health Proton Therapy Center underwent palliative to extremity bone metastases. Patients 18 years older with 1 3 painful metastases...
The COVID-19 pandemic has caused radiotherapy resource pressures and led to increased risks for lung cancer patients healthcare staff. An international group of experts in established this practice recommendation pertaining whether how adapt the pandemic.For ESTRO & ASTRO endorsed project, 32 contributed a modified Delphi consensus process. We assessed potential adaptations two scenarios. first, an early scenario risk mitigation, is characterized by altered risk-benefit ratio due their...
8506 Background: First line therapy options for advanced NSCLC without actionable molecular alterations include immunotherapy (IO) -/+ chemotherapy or alone. NRG-LU002 was a randomized phase II/III study assessing the benefits of local consolidative (LCT) when added to systemic as maintenance in management oligometastatic NSCLC. Methods: Eligible patients had metastatic with 3 fewer extracranial sites (excluding primary) exhibiting at least stable disease after 4 cycles 1 st therapy....
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidative destruction of erythrocyte ghost membranes catalyzed by the doxorubicin-iron complexCharles E. Myers, Luca Gianni, Charles B. Simone, Raymond Klecker, and GreeneCite this: Biochemistry 1982, 21, 8, 1707–1713Publication Date (Print):April 13, 1982Publication History Published online1 May 2002Published inissue 13 April 1982https://pubs.acs.org/doi/10.1021/bi00537a001https://doi.org/10.1021/bi00537a001research-articleACS PublicationsRequest...
Clinical medicine, particularly oncology, is progressing toward personalized care. Whereas the terms genomics, proteomics, transcriptomics, and metabolomics have dominated medicine for past couple decades, concept of radiomics was first described in 2012. This nascent has major implications cancer care involves extracting hundreds standardized quantifiable imaging characteristics from diagnostic computed tomography/magnetic resonance images. The central hypothesis that these libraries...
Machine learning algorithms that are both interpretable and accurate essential in applications such as medicine where errors can have a dire consequence. Unfortunately, there is currently tradeoff between accuracy interpretability among state-of-the-art methods. Decision trees therefore used extensively throughout for stratifying patients. Current decision tree algorithms, however, consistently outperformed by other, less-interpretable machine models, ensemble We present MediBoost, novel...
To analyze outcomes and predictors associated with proton radiation therapy for non-small cell lung cancer (NSCLC) in the National Cancer Database.The Database was queried to capture patients stage I-IV NSCLC treated thoracic from 2004 2012. A logistic regression model used determine utilization of therapy. The univariate multivariable association overall survival were assessed by Cox proportional hazards models along log-rank tests. propensity score matching method implemented balance...