- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Sexual function and dysfunction studies
- Erythrocyte Function and Pathophysiology
- Pancreatic function and diabetes
- Pediatric Urology and Nephrology Studies
- Neonatal skin health care
- Acupuncture Treatment Research Studies
- Blood properties and coagulation
- Hemoglobinopathies and Related Disorders
- Pregnancy-related medical research
- Gastrointestinal motility and disorders
- Pediatric health and respiratory diseases
- Dialysis and Renal Disease Management
- History of Medicine Studies
- Diverticular Disease and Complications
- Infant Health and Development
- Erythropoietin and Anemia Treatment
- Neonatal Health and Biochemistry
- Neurological Disorders and Treatments
- Regulation of Appetite and Obesity
- Complementary and Alternative Medicine Studies
- Hemoglobin structure and function
First Affiliated Hospital of Zhengzhou University
2007-2025
Xi’an Jiaotong-Liverpool University
2025
Qilu Hospital of Shandong University
2011-2014
Shandong University
2013
Zhengzhou University
2007
Henan University
2006
ABSTRACT Purpose: Currently, detethering surgery (DS) is the modality most extensively utilized to treat primary tethered cord syndrome (TCS). Disappointingly, some children without bladder impairment showed a deterioration of function after surgery, which critically influences health-related quality life. It was hypothesized that DS might have significant effect on and psychology. Therefore, purpose this study investigate life in with TCS. Materials Methods: A retrospective 83 patients aged...
Terminally ill children (TIC) in pediatric palliative care often encounter psychological deprivation due to isolation, impacting their self-discovery and identity formation. The Young Pioneer Voluntary Teams (YPVTs), initiated by the Ministry of Education China, address these challenges while also benefiting adolescents with enhanced self-esteem self-efficacy. However, current lack a standardized approach integrating youth volunteerism into raises concerns about potential negative impacts on...
Abstract Aims A pilot survey shows that primary nocturnal enuresis (PNE) prevalence has increased significantly during the past decade in Mainland China. Whether it is related to delay of elimination communication (EC) unclear. This study retrospectively investigated influence delayed EC on PNE children and adolescents mainland Methods cross‐sectional was performed by distributing 19 500 anonymous self‐administered questionnaires parents five provinces China from July 2017 October 2017. The...
To estimate the prevalence and severity of bed-wetting in 1-18-year-old Chinese children.A cross-sectional study was performed by using 13,515 self-administered questionnaires distributed to parents children Henan province. The determined. relationship wetting age, gender, community characteristics (rural or urban), arousal dysfunction, associated day-time symptoms (frequency, urgency, incontinence), family history were analyzed.There a response rate 87% (5,978 boys 5,786 girls). overall...
To investigate the possibility of using urodynamic variables to predict upper urinary tract dilatation (UUTD) in children with neurogenic bladder-sphincter dysfunction (NBSD).The study included 200 NBSD, whom 103 had UUTD and 97 did not; they were examined routine urological, neurological methods. The group was divided into three subgroups (group 1-3, from mild severe hydronephrosis). A risk score (URS) calculated, including a detrusor leak-point pressure (DLPP) >40 cmH2O, bladder compliance...
Abstract Objective To evaluate the effect of familial aggregation on children with PNE by evaluating nocturnal urine output, bladder, and arouse function. Patients Methods According to whether relatives family probands over three generations were affected PNE, forty‐five (FPNE), seventy sporadic (SPNE) ten normal lower urinary tract function but waiting for operation (control group) included. Questionnaire arousal from sleep (AS scores), bladder diary daytime urodynamic studies performed in...
Abstract Background: The aim of the present paper was to determine incidence primary nocturnal enuresis (PNE) among relatives Chinese children with PNE, inheritance pattern, and identify characteristics PNE positive family history. Methods: From July 2003 June 2004, an epidemiological survey on carried out by self‐administered questionnaires parents 5–18‐year‐old students in Henan Province, central China. A detailed history recorded order presence familial as defined any close relative...
To investigate the effect of losartan on preventing bladder fibrosis and protecting renal function in rats with neurogenic paralysis (NPB).Rats were assigned to transecting spinal nerves group (TSNG), + (LSTG), control (CG). On Day 32 postsurgery, capacity (BC), compliance (ΔC), leakage pressure (Pves.leak ) TSNG LSTG while BC, ΔC, threshold (Pves.thre CG measured by cystometry each cohort. Renal expression quantity Angiotensin Ⅱ (Ang II) blood detected, addition Ang II, II Type 1 receptor...
Purpose: To identify more accurate predictors of upper urinary tract dilatation (UUTD) in neurogenic bladder (NB) children, we studied the relationship among urodynamic parameters at different filling stages, detrusor leak point pressure (DLPP) and UUTD.Methods: A total 158 children (3–16 years) with NB were included then divided into 2 groups according to whether their diagnosis was complicated UUTD: UUTD group (39 patients) those without (control group, 119 patients). The phase 3 equal...
<i>Objective:</i> To evaluate the urodynamic parameters, development of bladder function and complications clean intermittent self-catheterization (CIC) in Chinese schoolchildren with neurogenic underactive bladder. <i>Methods:</i> Ninety-three children were successfully treated CIC or combined oxybutynin for two years follow-up. According to compliance before CIC, they subdivided into a normal (NBC) group low (LBC) group. Urodynamic parameters recorded....
Abstract To determine the prevalence of bladder and bowel dysfunction (BBD) its relationship with delayed elimination communication (EC) in children. A cross-sectional study was carried out kindergartens primary schools mainland China. total 10,166 children ranging from 4 to 10 years old were included. valid questionnaires collected, 409 diagnosed BBD. The overall 4.02% (409/10,166) decreased age, 6.19% at age 1.96% 10. With prolonged use disposable diapers (DDs), commencement usage EC a...
Congenital urinary tract obstruction is one of the most frequent malformations in fetuses or neonates, which usually causes profound impairment renal function including reductions both glomerular filtration rate (GFR) and tubular handling water solutes. Although can be released by surgical operation, child will suffer from diuresis for sometime. It has been reported that erythropoietin (EPO) could prevent down-regulation aquaporin-2 (AQP2) urinary-concentrating defects induced...
Obesity is a worldwide epidemic and has become public health priority for which there need effective treatments. It recognised as condition of low-grade systemic inflammation.1 Acupuncture may be cost-effective approach to the treatment obesity.2 ,3 However, question how acupuncture mechanistically exerts beneficial effects on obesity remains unanswered. A recent report provides evidence decreased serum haemorphin-7 in obese subjects.4 Haemorphin family endogenous …
Renal fibrosis is the major pathological changes of Chronic kidney disease (CKD). Piezo1, a mechanical sensitive ion channel, implicated in organ fibrosis. However, precise role Piezo1 CKD unknown. The aims this study were to identify that and its potential involvement mitochondrial dysfunction. We performed with agonist Yoda1, Bax inhibitor BAI1, GsMTx4 detected injury, fibrosis, apoptosis markers results showed levels apoptosis, dysfunction, injury increased TCMK-1 cells after treatment...