A5044764405- Dermatology and Skin Diseases
- Allergic Rhinitis and Sensitization
- Peripheral Artery Disease Management
- Spinal Cord Injury Research
- Asthma and respiratory diseases
- Vascular Procedures and Complications
- Long-Term Effects of COVID-19
- Traumatic Brain Injury Research
- Trauma Management and Diagnosis
- Food Allergy and Anaphylaxis Research
- Intensive Care Unit Cognitive Disorders
- Nerve Injury and Rehabilitation
- Aortic aneurysm repair treatments
- Cellular Mechanics and Interactions
- Cerebral Palsy and Movement Disorders
- Stroke Rehabilitation and Recovery
- Tumors and Oncological Cases
- Estrogen and related hormone effects
- Lipoproteins and Cardiovascular Health
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Transcranial Magnetic Stimulation Studies
- Vascular Malformations and Hemangiomas
- Cardiovascular Issues in Pregnancy
- Aortic Disease and Treatment Approaches
- Pain Management and Treatment
Linköping University
2020-2024
Linköping University Hospital
2024
Karolinska Institutet
2003-2023
Karolinska University Hospital
1992-2022
Few studies have reported the long-term health effects of COVID-19. The regional population-based Linköping COVID-19 study (LinCoS) included all patients hospitalised due to during first pandemic wave. Four months post-discharge, over 40% (185/433) experienced persisting symptoms and activity/participation limitations, indicating post-COVID-19 condition (PCC). present follow-up aimed determine recovery among these 24 post-admission. This prospective cohort from LinCoS with PCC at four...
Oral propranolol is widely prescribed as first-line treatment for infantile haemangiomas (IHs). Anecdotally, prescribing practice differs between centres.The Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce was founded to establish patterns use in IHs.Participating centres entered data on all their patients who had completed with oral IHs, using an online capture tool.The study cohort comprised 1097 children from 39 eight European countries. 76·1% were female and...
Summary Background The aetiology of atopic dermatitis (AD) is presumably multi‐factorial, with interactions between genetic and environmental factors. Objective To investigate the relation family history development AD up to 4 years. Methods Using annual questionnaires, we studied cumulative incidence in 0–4‐year‐olds a prospective birth cohort 4089. Atopic diseases parents siblings were recorded at birth. occurrence serum immunoglobulin E (IgE) antibodies inhalant food allergens was...
While atopic dermatitis (AD) usually presents early in life, few prospective studies focus on young children with AD. The objective of this study was to characterize, phenotypically and prospectively, From a community birth cohort 2,256 children, consecutive AD (n = 221) were followed 2 years age, when they re-examined screened for sensitization (skin-prick test foods; Phadiatop). Ninety-nine controls also examined. debuted during the first year 88% cases. At 2-year examination, had already...
Background: Eczema is a common chronic inflammatory skin disorder which shows strong genetic predisposition. To identify new potential molecular determinants of the disease pathogenesis, we performed gene expression study in an eczema mouse model. This analysis identified marked down regulation cornulin ( CRNN ), member epidermal differentiation complex, eczema‐like skin. We then investigated as candidate and studied its polymorphism patients. Methods: An phenotype was induced mice by...
To assess the prevalence of residual trans-lesion connectivity in persons with chronic clinically complete spinal cord injury (discompleteness) by neurophysiological methods.A total 23 adults sensorimotor injury, identified through regional registries registry Östergötland, Sweden.Diagnosis was verified standardized neurological examination. Then, a examination performed, comprising electroneurography, electromyography, sympathetic skin response and evoked potentials (sensory, laser motor)....
Abstract Background Atopic dermatitis (AD; OMIM#603165) and psoriasis (OMIM#177900) are two common inflammatory skin disorders. Both genetically complex, multifactorial do not follow a Mendelian pattern of inheritance. diseases share several genetic susceptibility loci such as the epidermal differentiation complex ( EDC ) on chromosome 1q21. Within , mutations in filaggrin FLG gene strongly associated with AD whereas no association has been replicated psoriasis. However, reduced levels have...
Summary Background Allergic rhinoconjunctivitis is a common complex disorder characterized by itching and irritation in the nose, bouts of sneezing, watery rhinorrhoea, nasal congestion itchy eyes with tears swelling. Like other atopic disorders such as allergic asthma dermatitis, development involves interactions genes environmental factors. Objective The purpose this study was to identify susceptibility loci for rhinoconjunctivitis. Methods We conducted genome‐wide linkage analysis using...
Objective: To report on the recommendations of an expert-based consensus indications, timing, and techniques aortic balloon occlusion (ABO) in management ruptured abdominal aneurysms (rAAA). Methods: Eleven facilitators created appropriate statements regarding study issues that were voted using a 4-point Likert scale with open-comment fields, by selected panel international experts (vascular surgeons interventional radiologists) 3-round modified Delphi procedure (study period: January-April...
Objective: To corroborate findings suggesting that spinally targeted paired associative stimulation improves upper extremity motor function in chronic incomplete spinal cord injury. Design: Prospective interventional study. Subjects: Five adults with tetraplegia. Methods: Participants received stimulation, combining peripheral nerve and navigated transcranial magnetic towards 1 arm (16 1-h sessions during 4 consecutive weeks, targeting the 3 large nerves). Manual muscle testing (MMT) was...
Background: This paper forms part of the Linköping COVID-19 Study (LinCoS) which includes all 745 individuals in Region Östergötland (RÖ) admitted to hospital for during March 1st – May 31st, 2020. report aimed at describing and objectivizing reported problems through clinical examination, determining required level rehabilitation sevices according complexity. Methods: In this ambidirectional cohort study, 185 who had concerning persisting symptoms were invited a multi-professional...
Abstract Background: Violence due to firearms is a major global public health issue and vascular injuries from are particularly lethal. The aim of this study was analyse population-based epidemiology firearm-related injuries. Methods: This retrospective nationwide epidemiological including all patients with firearm the national Swedish Trauma Registry (SweTrau) January 1, 2011 December 31, 2019. There were 71879 trauma registered during period, which 1010 identified (1.4%), 162 (16.0%) at...
Introduction: Patients with peripheral artery disease (PAD) are at increased risk for adverse cardiovascular and limb events impaired quality of life. Lifestyle factors, such as patient physical activity levels dietary habits, known factors. Limited data is available on the feasibility efficacy tailored PAD digital therapeutic programs, focused improving lifestyle (e.g. levels, sleep, stress, energy levels) medication adherence. Hypothesis: We assessed hypothesis that a program feasible...