A5072687531- Chronic Kidney Disease and Diabetes
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease Diagnosis and Treatment
- Acute Kidney Injury Research
- Advanced Glycation End Products research
- Inflammatory Biomarkers in Disease Prognosis
- Blood properties and coagulation
- Antibiotic Resistance in Bacteria
- Diabetes, Cardiovascular Risks, and Lipoproteins
- HIV-related health complications and treatments
- Bacterial biofilms and quorum sensing
- Diet, Metabolism, and Disease
- Muscle and Compartmental Disorders
- Gout, Hyperuricemia, Uric Acid
- Nutrition and Health in Aging
- Blood groups and transfusion
- Antimicrobial Resistance in Staphylococcus
- SARS-CoV-2 and COVID-19 Research
- Folate and B Vitamins Research
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Advanced Chemical Sensor Technologies
- Heme Oxygenase-1 and Carbon Monoxide
- Blood Pressure and Hypertension Studies
- IL-33, ST2, and ILC Pathways
Universidade Federal de Santa Maria
2015-2024
Universidade Federal do Rio Grande do Sul
2024
Hospital Universitário de Santa Maria
2011-2023
Centro Hospitalar de Trás os Montes e Alto Douro
2012-2023
Hospital de Clínicas de Porto Alegre
2023
Hospital Israelita Albert Einstein
2006-2020
Association for the Development of Douro Viticulture
2009
Hospital São Paulo
2006
Abstract Several COVID-19 vaccines have shown good efficacy in clinical trials, but there remains uncertainty about the of against different variants. Here, we investigate ChAdOx1 nCoV-19 (AZD1222) symptomatic a post-hoc exploratory analysis Phase 3 randomised trial Brazil (trial registration ISRCTN89951424). Nose and throat swabs were tested by PCR participants. Sequencing genotyping performed to determine lineages SARS-CoV-2 circulating during study. Protection any caused Zeta (P.2)...
Background: Enterobacteriaceae are major players in the spread of resistance to β-lactam antibiotics through action CTX-M β-lactamases. We aimed analyze diversity and genetic characteristics ESBL-producing Escherichia coli Klebsiella pneumoniae isolates from patients a Northern Portuguese hospital. Methods: A total 62 cefotaxime/ceftazidime-resistant E. (n = 38) K. 24) clinical were studied. Identification was performed by MALDI-TOF MS. Antimicrobial susceptibility testing against 13...
Klebsiella pneumoniae is a major pathogen implicated in nosocomial infections. Extended-spectrum β-lactamase (ESBL)-producing K . isolates are public health concern. We aim to characterize the type of β-lactamases and associated resistance mechanisms ESBL-producing obtained from blood cultures Portuguese hospital, as well determine circulating clones. Twenty-two cefotaxime/ceftazidime-resistant (CTX/CAZ R ) were included study. Identification was performed by MALDI-TOF MS antimicrobial...
Pseudomonas aeruginosa (PA) is a leading nosocomial pathogen and has great versatility due to complex interplay between antimicrobial resistance virulence factors. PA also turned into one the most relevant model organisms for study of biofilm-associated infections. The objective focused on analyzing susceptibility, genes, factors, biofilm formation ability thirty-two isolates PA. were characterized by following analyses: susceptibility 12 agents, presence genes factors in PCR assays,...
Abstract Introduction: Insulin resistance (IR) is associated with diabetic kidney disease (DKD), and normoalbuminuric patients may present renal tubular damage insulin (RTDAIR). In this context, the injury molecule-1 (KIM-1) emerges as a useful biomarker for assessing damage. Objective: To investigate role of KIM-1 in detection RTDAIR patients, well its relationship HOMA-IR. Methodology: This was cross-sectional study involving 82 T2DM, divided into two groups according to Laboratory tests...
Resumo Introdução: A resistência à insulina (RI) está associada doença renal diabética (DRD) e pacientes normoalbuminúricos podem apresentar lesão tubular (RTDAIR). Nesse contexto, a molécula de renal-1 (KIM-1) se apresenta como um marcador útil para avaliação da tubular. Objetivo: Investigar o papel do KIM-1 na detecção RTDAIR em normoalbuminúricos, bem sua relação com HOMA-IR. Metodologia: Estudo transversal envolvendo 82 DM2 divididos dois grupos pelo Foram realizados exames laboratoriais...
The aim of this study was to evaluate the effect annatto carotenoids intake associated a single high-calorie meal (high fat and high carbohydrate) in postprandial biochemical, inflammatory oxidative stress markers. Twelve healthy subjects (6 men, 6 women) were included randomised, controlled crossover study. Baseline blood samples collected from fasting that immediately received without carotenoid (placebo) or containing 1.2mg/kg bixin (BIX) 0.06mg/kg norbixin (NBIX). Blood taken 60, 120...
Red blood cell indices may add important prognostic information to risk stratification scores, such as Global Registry of Acute Coronary Events (GRACE) score. However, the incremental predictive value red distribution width (RDW) on this score has not been assessed. Therefore, aim study was assess whether RDW additional GRACE in prediction in-hospital mortality patients with acute myocardial infarction (AMI).A historic cohort investigated at University Hospital Santa Maria city, Brazil. The...
Background . Uric acid presents different roles in an organism. High serum uric concentrations may induce inflammatory pathways and promote kidney damage through mechanisms. Therefore, this study investigated the association among high concentrations, renal tubular damage, inflammation assessed via estimation of urinary injury molecule-1 (KIM-1) cytokines patients with type 2 diabetes (T2D). Methods Urinary KIM-1, IL-1, IL-6, IL-10, TNF-alpha, as well other biochemical parameters, were 125...
We sought to determine the resistance phenotypes for erythromycin and clindamycin mechanisms implicated in 93 Streptococcus agalactiae isolates recovered from healthy pregnant women. Susceptibility testing erythromycin, clindamycin, penicillin, cefotaxime, vancomycin, quinupristin-dalfopristin, choramphenicol, ofloxacin, meropenen was carried out by disc-diffusion test, E-test also applied clindamycin. The constitutive MLS(B) (cMLS(B)) inducible (iMLS(B)) phenotypes, respectively, as well M...