A5084740419- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Vibrio bacteria research studies
- Listeria monocytogenes in Food Safety
- Nail Diseases and Treatments
- Antifungal resistance and susceptibility
- Child Nutrition and Water Access
- Fungal Infections and Studies
- Hepatitis Viruses Studies and Epidemiology
- Microbial Inactivation Methods
- Animal Disease Management and Epidemiology
- COVID-19 and healthcare impacts
- Pharmaceutical and Antibiotic Environmental Impacts
- Urinary Tract Infections Management
- Global Health and Surgery
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Aquaculture disease management and microbiota
- Bacteriophages and microbial interactions
- COVID-19 Pandemic Impacts
- Global Maternal and Child Health
- COVID-19 epidemiological studies
- Ethics in Clinical Research
National Health Laboratory Service
2020-2024
National Institute for Communicable Diseases
2021-2024
University of Pretoria
2021
University of the Witwatersrand
2018
We conducted epidemiologic, trace-back, and environmental investigations used whole-genome sequencing to type Listeria monocytogenes isolates. A case was defined as laboratory-confirmed L. infection during the period from June 11, 2017, April 7, 2018.
Abstract Since February 2022, Malawi has experienced a cholera outbreak of >54,000 cases. We investigated 6 cases in South Africa and found that isolates linked to the were Vibrio cholerae O1 serotype Ogawa from seventh pandemic El Tor sublineage AFR15, indicating new introduction into south Asia.
Abstract An unexpected increase in gastroenteritis cases was reported by healthcare workers on the KwaZulu-Natal Coast, South Africa, January 2017 with >600 seen over a 3-week period. A case–control study conducted to identify source and risk factors associated outbreak so as recommend control prevention measures. Record review identified controls structured-telephonic interviews were obtain exposure history. Stool specimens collected from 20 along environmental samples both screened for...
We describe the molecular epidemiology of cholera in South Africa during 2018-2020. Vibrio cholerae O1 sequence type (ST) 75 recently emerged and became more prevalent than V. biotype El Tor pandemic clone. ST75 isolates were found across large spatial temporal distances, suggesting local spread.
The National Institute for Communicable Diseases in South Africa participates national laboratory-based surveillance human isolates of Salmonella species. Laboratory analysis includes whole-genome sequencing (WGS) isolates. We report on WGS-based enterica serovar Typhi ( Typhi) from 2020 through 2021. describe how WGS identified clusters enteric fever the Western Cape Province and epidemiological investigations associated with these clusters. A total 206 were received analysis. Genomic DNA...
Salmonella enterica serotype Enteritidis ( Enteritidis) is a major cause of foodborne disease outbreaks worldwide. In 2018, two concurrent gastroenteritis in one district South Africa were investigated. We describe the use whole-genome sequencing (WGS) analysis bacterial isolates to assist with investigation these outbreaks. Outbreak A affected children n =27) attending day-care centre, while outbreak B adults =16) who ate breakfast at same restaurant. was isolated from stool samples both...
Abstract Background In South Africa, the annual incidence of enteric fever averaged 0.1 per 100 000 persons between 2003 and 2018. During 2021 an increase in number cases was observed. An outbreak investigation conducted to determine magnitude source outbreak. Methods We performed a cross-sectional descriptive study. Data were collected through telephonic or face-to-face interviews with proxies via standardized case form. Whole genome sequencing on all Salmonella Typhi isolates. Drinking...
Our 24-month study used metagenomics to investigate antimicrobial resistance (AMR) abundance in raw sewage from wastewater treatment works (WWTWs) two municipalities Gauteng Province, South Africa. At the AMR class level, data showed similar trends at all WWTWs, showing that aminoglycoside, beta-lactam, sulfonamide and tetracycline was most abundant. differences were shown between municipalities, where Tshwane Metropolitan Municipality (TMM) WWTWs overall higher of compared Ekurhuleni (EMM)...
Abstract Background In sub-Saharan Africa, there is dearth of trained laboratorians and strengthened laboratory systems to provide adequate quality services for enhanced HIV control. response this challenge, in 2007, the African Centre Integrated Laboratory Training (ACILT) was established South Africa with a mission train staffs from countries high burdens diseases skills needed strengthen sustainable systems. This study undertaken assess transference newly gained knowledge other staff,...
Introduction: Coronavirus Disease 2019 (COVID-19) is a respiratory illness caused by severe acute syndrome coronavirus 2 (SARS-CoV-2). According to the World Health Organisation, modes of transmission for SARS-CoV-2 include contact, droplet and airborne has also been reported. On 16 March 2020, Nelson Mandela Bay District in Eastern Cape Province recorded its first case SARS-CoV-2, which was travel related. 21 over 1000 people attended funeral healthcare worker one townships within district....