A5102946969- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Abdominal Surgery and Complications
- Organ Transplantation Techniques and Outcomes
- Intestinal Malrotation and Obstruction Disorders
- Enhanced Recovery After Surgery
- Organ and Tissue Transplantation Research
- Infant Nutrition and Health
- Central Venous Catheters and Hemodialysis
- Transplantation: Methods and Outcomes
- Hematopoietic Stem Cell Transplantation
- Child Nutrition and Feeding Issues
- Congenital Anomalies and Fetal Surgery
- Digestive system and related health
- Organ Donation and Transplantation
- Intestinal and Peritoneal Adhesions
- Viral-associated cancers and disorders
- Gastroesophageal reflux and treatments
- Diet and metabolism studies
- Biomedical Ethics and Regulation
- Bariatric Surgery and Outcomes
- Immune Cell Function and Interaction
- Long-Term Effects of COVID-19
- Renal Transplantation Outcomes and Treatments
- COVID-19 Clinical Research Studies
Consejo Nacional de Investigaciones Científicas y Técnicas
2024
Favaloro University
2014-2024
Fundacion Favaloro Hospital Universitario
2010-2024
Favaloro Foundation
2019-2023
Hospital Italiano La Plata
2002
Abstract Background Short‐bowel syndrome remains the primary cause of intestinal failure (IF) in adult patients. We aim to report long‐term results medical and surgical rehabilitation a cohort patients with type III IF (III‐IF) develop formula predict parenteral nutrition (PN) independency. Methods used retrospective analysis prospective database for III‐IF undergoing autologous gastrointestinal reconstruction surgery (AGIRS) from March 2006 August 2018. Analyzed variables included...
Normal small bowel length (SBL) has been reported within a wide range, but never studied in cohort of either pediatric or adult deceased donors. Between 5/2006 and 2/2011, SBL was measured all grafts procured for intestinal transplantation at single center used isolated transplant (15) multiorgan transplants (5) employing standardized method. the only not significantly different variable among donors divided by age 16. Furthermore, were classified 3 groups: group 1: Height < 70 cm, 2: 71-150...
Teduglutide, a semisynthetic analogue of glucagon-like peptide-2 (sGLP-2), increases intestinal absorption fluids and nutrients, reducing the need for parenteral nutrition (PN). This report aims to describe our experience with sGLP-2 in cohort adult patients short-bowel syndrome.This is prospective observational study on initially evaluated specialized rehabilitation program that received from June 2014 March 2020.Autologous gastrointestinal reconstruction surgery (AGIRS) was performed 108...
Short bowel syndrome (SBS) is considered a low prevalence disease. In Argentina, no registries are available on chronic intestinal failure (CIF) and SBS. This project was designed as the first national registry to report adult patients with this disease.A prospective multicenter observational created including CIF/SBS from approved centers. Demographics, clinical characteristics, nutrition assessment, home parenteral (HPN) management, surgeries performed, medical treatment, overall survival,...
Acute cellular rejection (ACR) and infections are leading causes of graft loss death in intestinal transplant patients. Our aim was to evaluate the impact maintenance immunosuppressive therapies on expression pro-inflammatory mediators small bowel at ACR diagnosis.We analyzed levels Th1-associated genes, IFNG, CXCL10, CXCL11 by qPCR 46 selected biopsies unequivocally assigned mild (n = 14) or normal histopathology clinical condition 32) from 15 patients receiving two different (IS) schemes....
Kaposi's sarcoma (KS) is an infrequent vascular neoplasm commonly diagnosed as isolated cutaneous lesion that can involve other organs. So far, there are no data in the literature about development of KS after intestinal transplant.In this study, authors describe a case "visceral KS" with pulmonary and involvement perform systematic review reports single-center series identified MEDLINE.This was 42-year-old man, visceral 9 months receiving transplant. He successfully treated combination...
Abstract Exfoliative rejection is a severe complication after intestinal transplant. The assessment of mucosa histology restricted to the area reached by endoscopy. We aim evaluate serum albumin ( SA ) value as parameter graft damage and clinical prognosis in exfoliative E x R ). present study retrospective analysis 11 episodes occurred cohort 26 patients. levels were measured 24 h diagnosis twice week thereafter then correlated with parameters histological recovery HR During , all patients...
The understanding of the mechanisms for development ascites has evolved over years, involving liver, peritoneum, heart, and kidneys as key responsible its formation. In this article, we review pathophysiology formation, introducing role intestine a major production through "a game changer" case.
Abstract Background Short bowel syndrome is considered a low prevalence disease. The scant information available about intestinal failure in Latin America was the driving force to expand this registry. Methods A prospective, multicenter observational registry created for patients with chronic short at specialized centers America. Demographics, clinical characteristics, nutrition assessment, parenteral management, rehabilitation, related complications, outcome, and survival were analyzed....
Background: Abdominal wall (AW) closure remains an important challenge in intestinal transplant (ITx) field due to loss of abdominal domain. As alternative the various techniques AW management, we proposed use rectus fascia (ARF). We aim present our long-term experience surgical management patients (pts) receiving ARF at time ITx. Methods: This is a retrospective report pts that received during isolated, combined, or multivisceral Tx (MTV) single centre from May 2006 Dec 2013. Results: 12/40...
Background: Type III Intestinal Failure (IF) due to short bowel syndrome remains a rare condition. Few registries worldwide are able collect prospective information on diagnoses, management, complications and outcomes in the subject. Aim: report progression, updated results future steps of RESTORE amendment registry. Methods: A multicenter observational registry was created 2017 for adult patients with type III-IF SBS Argentina (RESTORE). In May 2020, it amended order include pediatric...
Restore Gruop. Intoduction: Type III intestinal failure is a highly invalidating condition which requires parenteral nutrition (PN) and multidisciplinary health care, generating high costs to the system. The most frequent cause short bowel syndrome (SBS). Less than 50% of patients reach rehabilitation within period 2 5 years, depending on anatomy type post-surgical length, rest must continue under PN until Transplantation indicated. Over last years use semisynthetic analog GLP2 has changed...
Introduction: The abdominal wall (AW), may be severely compromised in the vast majority of intestinal and multiorgan transplant candidates, sometimes as consequence a complex liver transplant. Multiple options have been described to overcome this problem. Our aim is report largest longest-term follow-up patients that received an AW, non-Vascularized, non-Composite allograft (AW-non-V non-CA), it has proposed call Abdominal Rectus Fascia; after liver, or transplantation at single center....
Introduction: Intestinal Failure (IF) is defined as “the reduction of gut function below the minimum necessary for absorption macronutrients and/or water and electrolytes to maintain health growth”. The primary pathophysiological mechanism in adults (ad) patients (pts) due short syndrome (SBS). probability weaning off parenteral nutrition (PN) has been reported be 50%, considering this possibility cannot achieve after 2 years. Those pts would benefit from an adequate evaluation support at a...
Introduction: III-IF is a highly invalidating condition which requires long term parenteral nutrition (PN).The most frequent cause post-surgical short bowel syndrome (SBS). Less than 50% of pts would be able to reach rehabilitation within 2 years. Favorable outcomes rely on, intestinal length (PSIL), anatomy type (PSAT) and the presence ICV. Over last years use TED has changed course this disease, challenging classically accepted predictors for favorable outcome. Aim: Report experience using...
Introduction: Intestinal transplant (ITx) remains the last therapeutic alternative for patients (pts) with intestinal failure (IF). Although pt and graft survival have improved overtime, there are few reports of long term outcomes individual pts surviving more than 10 years functional grafts; is no results report from Latin-America. Aim: to describe outcome those underwent ITx at our center graft. Materials methods: This a retrospective analysis survivors starting in May 2006. Diagnoses,...