A5024587926- BRCA gene mutations in cancer
- Genetic factors in colorectal cancer
- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Cancer Genomics and Diagnostics
- Ovarian cancer diagnosis and treatment
- Genomics and Rare Diseases
- PARP inhibition in cancer therapy
- Telemedicine and Telehealth Implementation
- DNA Repair Mechanisms
- Vaccine Coverage and Hesitancy
- Reconstructive Surgery and Microvascular Techniques
- Nutrition, Genetics, and Disease
- Health Literacy and Information Accessibility
- COVID-19 and healthcare impacts
- Mesenchymal stem cell research
- Breast Implant and Reconstruction
- Prenatal Screening and Diagnostics
- Health Systems, Economic Evaluations, Quality of Life
- Social Media in Health Education
- Economic and Financial Impacts of Cancer
- Colorectal and Anal Carcinomas
- Healthcare Systems and Public Health
- Colorectal Cancer Screening and Detection
- Mobile Health and mHealth Applications
Cornell University
2021-2024
Weill Cornell Medicine
2021-2024
Weill Cornell Medical College in Qatar
2021-2024
Faculty of 1000 (United States)
2024
Gynecologic Oncology Group
2022-2023
Presbyterian Hospital
2022-2023
ObjectivesApproximately 1% of individuals have a hereditary cancer predisposition syndrome, however, the majority are not aware. Collecting family history (CFH) can triage patients to receive genetic testing. To rigorously assess different methods CFH collection, we compared web-based tool (WBT) usual care (clinician collects CFH) in randomized controlled trial.MethodsNew gynecologic oncology (seen 9/2019–9/2021) were one three arms 2:2:1 allocation ratio: 1) clinician 2) WBT completed at...
(Abstracted from Am J Obstet Gynecol 2024;231:330.e1–330.e14) BRCA1 gene mutations significantly increase the risk of breast, ovarian, and pancreatic cancer. Early interventions, such as screening, chemoprevention, risk-reducing surgeries—including bilateral mastectomy (RRBM) salpingo-oophorectomy (rrBSO)—have been shown to lower cancer mortality.
Preconception and pregnancy represent a unique window of opportunity for women to engage with the health care system. This article explores possibility offering testing cancer‐associated pathogenic variants on obstetrical carrier screening panels.
Cascade genetic testing for hereditary cancer syndromes offers affected relatives the opportunity to pursue screening and risk-reducing surgery thus reduces morbidity mortality. The purpose of this study was measure long-term utilization targeted prevention quality life among at-risk offered clinician-facilitated cascade testing.
To date, breast reconstruction after mastectomy essentially uses flap- or prosthetic-based surgery. Autologous fat grafting (AFT) largely used in conservative surgery is considered an additional technique reconstruction. The aim of this retrospective study was to report our experience AFT as a stand-alone method for immediate reconstruction.Fifteen patients requiring radical underwent since 2014. Previous irradiation not contraindication. Procedures, complications, and cosmetic results were...
Background: Lynch syndrome (LS) is an autosomal dominant hereditary condition associated with a genetic predisposition to several cancers. Prior studies have shown increased risk of gastric cancer (GC) in LS patients. The aim this study was synthesize the evidence for across syndrome-associated mutations and assess diagnostic utility endoscopic screening these Methods: A systematic literature review meta-analysis LS-associated conducted accordance PRISMA guidelines GRADE methodology....
The literature demonstrates that the quality of cancer family history (CFH) as currently collected in outpatient setting is inadequate to assess disease risk. Prior implementation a web-based application for collection, we aimed review CFH gynecologic oncology clinic and determine contributing patient factors. Medical records were reviewed 200 new patients presenting between 4/2019–7/2019. was during interview evaluated inclusion eight elements based on standards set by genetics community....
10594 Background: Germline pathogenic gene variants (PGV) in homologous recombination deficiency (HRD) genes are traditionally associated with breast, ovarian, pancreatic, prostate and melanoma skin cancer. Recent evidence suggests other cancers may also be these genes. We analyzed the prevalence of somatic HRD mutations common, non-hereditary breast ovarian cancer (HBOC) incident US. Methods: Data were collected from American Association for Cancer Research’s (AACR) Project Genomics...
There is a dearth of literature studying restless leg syndrome (RLS) among pregnant patients in Pakistan. The objective this study was to determine the prevalence and associated factors RLS Pakistani patients. It conducted 2018 478 women attending ante-natal check-up outpatient department five hospitals Karachi, Individuals were interviewed for socio-demographic information, key criteria its factors. reported 54 (11%) individuals based on International Restless Legs Syndrome Study Group...