A5069603262- Transcranial Magnetic Stimulation Studies
- Glioma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Intraoperative Neuromonitoring and Anesthetic Effects
- Spinal Cord Injury Research
- Meningioma and schwannoma management
- Moyamoya disease diagnosis and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer, Hypoxia, and Metabolism
- Neuroscience and Neuropharmacology Research
- Nerve injury and regeneration
- Advanced MRI Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
- Neuroscience and Neural Engineering
- Functional Brain Connectivity Studies
- Brain Metastases and Treatment
- Spinal Dysraphism and Malformations
- EEG and Brain-Computer Interfaces
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- Neurosurgical Procedures and Complications
- Epilepsy research and treatment
- Neurogenesis and neuroplasticity mechanisms
- Head and Neck Surgical Oncology
Oita University
2015-2024
Oita University Hospital
2002-2023
Central Brain Tumor Registry of the United States
2014
Helsinki University Hospital
2005-2008
Ministry of Education, Culture, Sports, Science and Technology
2007
University of Virginia
1996-1999
Oita Medical Center
1989-1990
Toshiba (Japan)
1986-1987
Functional mapping of the human motor cortex related to hand and foot area was carried out using focal magnetic stimulation brain. The basic idea localized brain is concentrate induced eddy currents locally in vicinity a target by pair opposing pulsed fields. A figure-eight coil positioned outside head so that time-varying fields could pass through opposite directions around target. It observed an optimum direction stimulating for neural excitation exists each functional cortex. maps were...
<h3>BACKGROUND AND PURPOSE:</h3> Pulsed arterial spin-labeling, DTI, and MR spectroscopy provide useful data for tumor evaluation. We evaluated multiple parameters by using these pulse sequences the Ki-67 labeling index in newly diagnosed supratentorial gliomas. <h3>MATERIALS METHODS:</h3> All 32 patients, with grade II (3 each of diffuse astrocytoma, oligodendroglioma, oligoastrocytoma), III anaplastic astrocytomas, 4 oligodendrogliomas, 1 IV (14 glioblastomas glioblastoma an...
Patterns of neuronal activity that induce synaptic plasticity and memory storage activate kinase cascades in neurons are thought to be part the mechanism for modification. One such cascade involves induction phosphorylation ribosomal protein S6 due activation AKT/mTOR via a different pathway, MAP kinase/ERK1/2. Here, we show can also strongly activated by high frequency repetitive transcranial magnetic stimulation (hfrTMS). HfrTMS was delivered lightly anesthetized rats using protocol is...
Abstract Background Adjuvant treatment with Gliadel wafers may prolong overall survival (OS) for malignant glioma patients without increasing toxicity. In Japan, the long-term OS of these treated 7.7 mg implants has not been studied. We evaluated and prognostic factors that might affect in Japanese who received implant. Methods This observational, long-term, postmarketing surveillance was an extension a previous surveillance. Data were collected through case report forms at 2 3 years after...
Progressive tissue necrosis is a process unique to the injured mammalian spinal cord which often leads gradually increasing cavitation and enlargement of lesion. To evaluate role neuronal degeneration in initiating this response, histopathological changes were compared C57BL WldS (delayed Wallerian mutation) mice. The was crushed at T8, producing primary lesion site trauma secondary extending rostrocaudally dorsal columns (where long ascending descending fiber tracts undergo degeneration)....
To investigate the efficacy of encephalo-duro-arterio-synangiosis (EDAS) for treatment pediatric moyamoya disease, we analyzed 11 patients who were followed up more than 100 months. Among 22 sides in patients, performed EDAS on 16 10 pa- tients, encephalo-duro-arterio-myo-synangiosis (EDAMS) 5 4 and encephalo-myo-synangiosis (EMS) 1 side. Of 8 showed normal development had no neurological deficit. The remaining 3 mild to moderate deficits, but these cases, pre- perioperative insults...
Reactive changes in macrophages/microglia and astrocytes were evaluated following spinal cord injury normal mice of the C57BL/6J strain carrying a mutation (Wlds) which delays onset Wallerian degeneration damaged axons. Crush injuries produced at T8 level by using an extradural approach; animals allowed to survive for 2 days 12 weeks, cords prepared immunocytochemistry antibodies against Mac1 glial fibrillary acidid protein (GFAP). In mice, Mac1-positive macrophages accumulated site 4...
The goal of this study was to compare motor evoked potentials recorded from muscles (muscle MEPs or corticomuscular MEPs) with corticospinal the cervical epidural space (spinal assess their efficacy in intraoperative monitoring function.Muscle and spinal were simultaneously during surgery 80 patients harboring brain tumors. Each case assigned one four groups according final changes MEPs: (1) Group A, which there an increased amplitude muscle MEP 13 wave (12 cases); (2) B, no significant...
Object. Data in the present study demonstrate that repetitive transcranial magnetic stimulation (rTMS) induces ischemic tolerance against delayed neuronal death (DND) of hippocampal neurons following an otherwise lethal insult. Methods. Various regimens rTMS were delivered to adult gerbils at various times prior episode ischemia induced by transient (5-minute) bilateral common carotid artery (CCA) occlusion. The extent DND CA1 region hippocampus was assessed quantitatively 7 days after...
Several studies have investigated neural correlates of aesthetic appreciation for paintings but to date the findings been heterogeneous. This heterogeneity may be attributed previous studies' measurement not only beauty also motifs paintings. In order better elucidate paintings, it seems necessary compare and photographic analogues which included corresponding real images. We prepared famous painters' pictures their were set up resemble each painting in investigate hypothesis that there...
Abstract Sialic acid-binding immunoglobulin-like lectin-15 (Siglec-15) is a new immune checkpoint molecule and its role of primary central nervous system lymphoma (PCNSL) tumor microenvironment has been unclear. We explored the Siglec-15 programed death-ligand 1 (PD-L1) expression in tissues analyzed association between these molecules overall survival newly diagnosed PCNSL. A total 60 patients with diffuse large B-cell PCNSL were included this study. The PD-L1 on cells, intratumoral...
A 3.5" double-sided 4MB flexible disk and drive has been developed employing Toshiba's barium ferrite perpendicular recording medium without using a track-following servo. High storage capacity, four times higher than that for conventional 1MB drive, obtained by increasing linear density to 35 kBPI pre-erase heads, together with high techniques, such as head/media contact azimuth alignment. Track is 135 TPI, the same unit, so downward compatibility, capability of reading 1 MB disk, obtained....